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Dietary modulation of oxylipins in cardiovascular disease and aging [PDF]

open access: yesAmerican Journal of Physiology - Heart and Circulatory Physiology, 2017
Oxylipins are a group of fatty acid metabolites generated via oxygenation of polyunsaturated fatty acids and are involved in processes such as inflammation, immunity, pain, vascular tone, and coagulation.
Stephanie P B Caligiuri   +2 more
exaly   +2 more sources
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Oxylipins and oxylipin synthesis pathways in fungi

Applied Biochemistry and Microbiology, 2017
Oxylipins are a family of oxygenated fatty acids that are very diverse with regard to origin, structure, and functions. These compounds are found in almost all living beings and serve both as autoregulators of the development of organisms and as communication molecules.
S Yu Filippovich   +2 more
exaly   +2 more sources

Role of oxylipins in cardiovascular diseases [PDF]

open access: yesActa Pharmacologica Sinica, 2018
Globally, cardiovascular diseases (CVDs) are the number one cause of mortality. Approximately 18 million people died from CVDs in 2015, representing more than 30% of all global deaths. New diagnostic tools and therapies are eagerly required to decrease the prevalence of CVDs related to mortality and/or risk factors leading to CVDs.
Mohammed A Nayeem, Nayeem Mohammed A
exaly   +3 more sources

Regulation of oxylipin synthesis

Biochemical Society Transactions, 2000
Two very common groups of oxylipins formed in plants involve the conversion of fatty acid hydroperoxides, such as hydroperoxy-octadecatrienoic acid, into further metabolites by allene oxide synthase and hydroperoxide lyase. Both of these oxylipin branch pathways appear to be ubiquitous or nearly so in plants, but the relative activities of these two ...
D F, Hildebrand   +2 more
openaire   +2 more sources

Oxylipin analysis methods

The Plant Journal, 2006
SummaryPractical guidelines for monitoring and measuring compounds such as jasmonates, ketols, ketodi(tri)enes and hydroxy‐fatty acids as well as detecting the presence of novel oxylipins are presented. Additionally, a protocol for the penetrant analysis of non‐enzymatic lipid oxidation is described. Each of the methods, which employ gas chromatography/
Martin J, Mueller   +4 more
openaire   +2 more sources

Bioprospecting for novel oxylipins in fungi: The presence of 3-hydroxy oxylipins in Pilobolus

Antonie van Leeuwenhoek, 2001
As previously found in various members of the Mucorales, 3-hydroxy oxylipins in Mucor genevensis are associated with the sporangia, i.e. mainly the columella structure and between aggregating sporangiospores. To determine if this phenomenon is also true in distantly related members, the mucoralean fungus Pilobolus was examined.
J L, Kock   +9 more
openaire   +2 more sources

Brominated Oxylipins and Oxylipin Glycosides from Red Sea Corals

European Journal of Organic Chemistry, 2002
AbstractEight new brominated oxylipins 1−8, including two glycosides, were isolated from the Red Sea invertebrates Dendrophyllia sp., Dendronephthya sp. (red variety), Dendronephthya sp. (yellow variety), and Tubipora musica. Their structures were elucidated mainly on the basis of NMR spectroscopic data.
Tomáš Řezanka, Valery M. Dembitsky
openaire   +1 more source

Method optimization of oxylipin hydrolysis in nonprocessed bovine milk indicates that the majority of oxylipins are esterified

Journal of Food Science, 2021
Abstract The oxidation of polyunsaturated fatty acids produces bioactive primary oxidation products known as oxylipins. In many biological matrices, the majority of oxylipins are bound (i.e. esterified), and a relatively small proportion (<10%) exists in the free form.
Bianca Ferraz, Teixeira   +4 more
openaire   +2 more sources

Targeting esterified oxylipins by LC–MS - Effect of sample preparation on oxylipin pattern

Prostaglandins & Other Lipid Mediators, 2020
A major part of oxygenated metabolites of polyunsaturated fatty acids - i.e. eicosanoids and other oxylipins - in biological samples is found in the esterified form. Yet, their biological role is only poorly understood. For quantification of esterified oxylipins in biological samples current protocols mostly apply alkaline hydrolysis with or without ...
Annika I, Ostermann   +5 more
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The regulatory functions of oxylipins in fungi: A review

Journal of Basic Microbiology, 2023
AbstractQuorum sensing (QS) is a communication mechanism between microorganisms originally found in bacteria. In recent years, an important QS mechanism has been discovered in the field of fungi, namely, the lipoxygenase compound oxylipin of arachidonic acid acts as a QS molecule in life cycle control, particularly in the sexual and asexual development
Huiqian Liu   +3 more
openaire   +2 more sources

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