Results 91 to 100 of about 19,519,160 (297)
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
On the galloping instability of two-dimensional bodies having elliptical cross sections.
, 2010 Galloping, also known as Den Hartog instability, is the large amplitude, low frequency oscillation of a structure in the direction transverse to the mean wind direction.
Alonso Rodrigo, Gustavo +3 more
core +1 more source
Differential cargo mobilisation within Weibel-Palade bodies after transient fusion with the plasma membrane. [PDF]
, 2014 Inflammatory chemokines can be selectively released from Weibel-Palade bodies (WPBs) during kiss-and-run exocytosis. Such selectivity may arise from molecular size filtering by the fusion pore, however differential intra-WPB cargo re-mobilisation ...
Knipe, Laura +19 more
core +1 more source
Transgenic mouse model for the formation of Hirano bodies
BMC Neuroscience, 2011 Background Hirano bodies are actin-rich cytoplasmic inclusions found predominantly in the brain in association with a variety of conditions including aging and Alzheimer's disease.
Stramiello Michael +4 more
doaj +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
White Book on Physical and Rehabilitation Medicine in Europe. Introductions, Executive Summary, and Methodology [PDF]
, 2018 The White Book (WB) of Physical and Rehabilitation Medicine (PRM) in Europe is produced by the 4 European PRM Bodies (European Academy of Rehabilitation Medicine - EARM, European Society of PRM - ESPRM, European Union of Medical Specialists - PRM Section,
Ceravolo Maria Gabriella +2 more
core +1 more source
Geometric properties of the family of p-parallel bodies
Analysis and Geometry in Metric SpacesWe study geometric properties of the family of p-parallel bodies of a convex body K with respect to a gauge body E. In particular, we investigate various regularity properties of their boundaries by means of their 0-extreme vectors, aiming for extensions
Hernández Cifre María A. +2 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
, 2002 Background: Dementia with Lewy bodies (DLB) is one of the main differential diagnoses of Alzheimer's disease (AD). Key pathological features of patients with DLB are not only the presence of cerebral cortical neuronal loss, with Lewy bodies in surviving ...
Livingston, G +9 more
core
Clinical and Translational MedicineLung cancer remains one of the leading causes of cancer‐related deaths worldwide, and a growing body of evidence suggests that RNA modifications, including methylation, play a critical role in its progression.
Haiyang Wang +7 more
doaj +1 more source