Changes in Purkinje cell firing and gene expression precede behavioral pathology in a mouse model of SCA2. [PDF]
, 2012 Spinocerebellar ataxia type 2 (SCA2) is an autosomal dominantly inherited disorder, which is caused by a pathological expansion of a polyglutamine (polyQ) tract in the coding region of the ATXN2 gene.
Hansen, Stephen T +3 more
core +1 more source
Some properties of p-cross-section bodies and generalazation(p-截面体的性质与推广)
Zhejiang Daxue xuebao. Lixue ban, 2010 对p≥-1, GARDNER R J和GIANNOPOULOS A A引进了p-截面体CpK,并就p的不同取值,对CpK的凸性作了探讨.首先证明了CpK的一些性质,诸如原点对称的n维椭球E的p-截面体是它的极体的一个伸缩、CpCqE=CqCpE, V(CnK) =V(IK)等.而后通过探讨混合径向平均体Rp(K, L)与混合p-截面体Cp(K, L)的相关性,将p-截面体的一些性质推广到了Cp(K, L),并证明了当K和L是En中的凸体且K⊆L时, C1(K, L)是一个凸体.
SHENYa-jun(沈亚军)
doaj +1 more source
New p-terphenyls from the fruiting bodies of Pseudomerulius curtisii and their antioxidant activity [PDF]
, 2015 Byung Soon Hwang +2 more
openalex +1 more source
Functionally distinct roles for eEF2K in the control of ribosome availability and p-body abundance [PDF]
, 2021 Patrick Smith +5 more
openalex +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Effective run-and-tumble dynamics of bacteria baths
, 2013 {\it E. coli} bacteria swim in straight runs interrupted by sudden reorientation events called tumbles. The resulting random walks give rise to density fluctuations that can be derived analytically in the limit of non interacting particles or ...
Angelani, L. +2 more
core +1 more source
Nonsense mutations in alpha-II spectrin in three families with juvenile onset hereditary motor neuropathy [PDF]
, 2019 Distal hereditary motor neuropathies are a rare subgroup of inherited peripheral neuropathies hallmarked by a length-dependent axonal degeneration of lower motor neurons without significant involvement of sensory neurons.
Asselbergh, B +10 more
core +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Nonsense-mediated mRNA decay in human cells: mechanistic insights, functions beyond quality control and the double-life of NMD factors [PDF]
, 2018 Nonsense-mediated decay is well known by the lucid definition of being a RNA surveillance mechanism that ensures the speedy degradation of mRNAs containing premature translation termination codons.
Kleinschmidt, Nicole +5 more
core
Carlino, Andrea: Paper bodies: a catalogue of anatomical fugitive sheets 1538-1687. Transi, by Noga Arikha. London, Wellcome Institute for the History of Medicine, 1999. XVI, 352 p. 111. (Medical History, Supplement No. 19). £ 32.-; $ 50.-. ISBN 0-85484-069-9. [PDF]
, 2002 Teresa Huguet Termes
openalex +1 more source