Results 131 to 140 of about 19,519,160 (297)
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Haunted Bodies : Visual Cultures of Anorexia [PDF]
Thin bodies have been the centre of much controversy in recent years. Feminist critiques of popular culture, as well as popular feminist movements, have called attention to the ways in which oppressive ideals of feminine beauty have increasingly become ...
Ferreday, Debra
core
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
The gaze of law: technologies, bodies, representation
Book synopsis: The body occupies a prime position in contemporary theoretical work, yet still there is no consensus on exactly what it is and what constitutes it.
Moran, Leslie
core
Dynamic "Cap"-abilities of P-bodies and the XRN1-EDC4 axis. [PDF]
Malsick LE, Wilusz J.
europepmc +1 more source
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Relating the Biogenesis and Function of P Bodies in Drosophila to Human Disease. [PDF]
Wilby EL, Weil TT.
europepmc +1 more source
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
This study explored the physicochemical characterization of several components of water hyacinth and its biogas potential in batch and semi-continuous mode.The effect of the bioslurryfrom the continuous digesters were evaluated on the crop biomass yield.
Tewodros Mulu +11 more
doaj +1 more source

