Results 211 to 220 of about 20,489,060 (330)

Effects of hypoxia on the expression and function of P-gp in Caco-2 cells. [PDF]

Zhong Nan Da Xue Xue Bao Yi Xue Ban, 2023
Zhao A, Mu H, Yao W, Chang X, Li W, Wang R.   +5 more
europepmc   +1 more source

Snail-Induced Epithelial-to-Mesenchymal Transition Enhances P-gp-Mediated Multidrug Resistance in HCC827 Cells.

Journal of Pharmacy and Science, 2017
Takumi Tomono, K. Yano, T. Ogihara
semanticscholar   +1 more source

Both P-gp and MRP contribute to drug resistance in AML [PDF]

Leukemia, 1998
O, Legrand, G, Simonin, R, Zittoun, J P, Marie   +3 more
openaire   +2 more sources

Selective Inhibition of Integrin β3 Topology Provides a Safer Antithrombotic Strategy

Advanced Science, EarlyView.
Current integrin αIIbβ3 inhibitors effectively reduce thrombosis but also increase bleeding risk. During thrombosis, high shear blood flow can directly activate the integrin αIIbβ3 via a distinct topological change in the β3 transmembrane domain, independent of hemostatic platelet signaling.
Joonha Lee, Chul‐Gyun Lim, Pothiappan Vairaprakash, Jong‐Min Kim, Jiyoon Kim, Ji‐Young Park, Klaus M. Hahn, Hyunbo Shim, Hae Woong Choi, Tobias S. Ulmer, Soon Jun Hong, Chungho Kim   +11 more
wiley   +1 more source

Mapping the Role of P-gp in Multidrug Resistance: Insights from Recent Structural Studies. [PDF]

Int J Mol Sci
Tia ST, Luo M, Fan W.
europepmc   +1 more source

Recent Developments of P-gp Inhibitors [PDF]

, 2013
openaire   +1 more source

Cars2‐Mediated Cysteine Catabolism Drives Brown Fat Development and Thermogenesis Through Persulfidating EBF2

Advanced Science, EarlyView.
We demonstrate that Cars2, a cysteine catabolic enzyme in mouse iBAT, is critical for cold tolerance and brown adipocyte differentiation. Through its CPERS activity, Cars2 produces CysSSH/H2S to induce EBF2 persulfidation, promoting its interaction with PPARγ and BRG1 to enhance thermogenic gene expression.
Xin Peng, Hongyong Song, Yin Long, Kaimin Wu, Yinkun Fu, Wenkai Zhou, Wenyan Li, Zhe Shi, Xu‐Yun Zhao   +8 more
wiley   +1 more source

Expression and interaction of RNA binding protein HuR with multidrug transporters (P-GP, MRP1, and ABCG2) in chemoresistant breast and colorectal cancer cells. [PDF]

J Genet Eng Biotechnol
Nath SD, Akash MMH, Tanim MTH, Akhteruzzaman S, Mostafa MG, Sajib AA.   +5 more
europepmc   +1 more source

Role of P-Gp in Treatment of Cancer

Journal of Cancer Therapy
Venkata Sai Nithin Reddy Yendapalli, Kelley Williams, Terry Oroszi   +2 more
openaire   +1 more source

A Rational Optimization Approach for the Development of a Multiplexed Lateral Flow Immunoassay: Detection of Nonepithelial Ovarian Cancer Markers in Human Serum

Advanced Science, EarlyView.
This study outlines the developmental pipeline of a multiplexed nanozyme‐based lateral flow immunoassay for the purpose of ovarian germ cell tumor detection. It demonstrates the application of a design of experiments optimization approach for nanozyme probe conjugate development.
Aida Abdelwahed, Carl E. Eskildsen, Luca Panariello, André Shamsabadi, Christy J. Sadler, Edmund H. Wilkes, Federico Galvanin, Yuxi Cheng, Sara Carvalho, Srdjan Saso, Molly M. Stevens   +10 more
wiley   +1 more source