Results 191 to 200 of about 243,388 (247)

An Engineered Supramolecular Pathway for Enhanced Electrochemiluminescence

Advanced Science, EarlyView.
A supramolecular electrochemiluminescent (ECL) system is presented in which cucurbit[7]uril (CB7) is covalently linked to [Ru(bpy)3]2+, forming a recognition‐responsive emitter. Host‒guest preorganization of tri‐n‐propylamine enables intramolecular ECL, boosting intensity by 162% compared to the standard system.
Maria Vittoria Balli, Madhurima Jana, Chiara Capolungo, Patrick Gruhs, Pierre Picchetti, Giovanni Valenti, Frank Biedermann, Luca Prodi   +7 more
wiley   +1 more source

Development of PBPK Population Model for End-Stage Renal Disease Patients to Inform OATP1B-, BCRP-, P-gp-, and CYP3A4-Mediated Drug Disposition with Individual Influencing Factors. [PDF]

Pharmaceutics
Wu Y, Kong W, Li J, Xiang X, Liang H, Liu D.   +5 more
europepmc   +1 more source

Dual‐Functional Membranes With Interfacial MXene/PFSA Nanoarchitectures for Low Hydrogen Permeation in Water Electrolysis and Reduced Vanadium Ion Crossover in Flow Batteries

Advanced Science, EarlyView.
A PFSA/MXene composite membrane is developed for both PEMWE and VRFB applications. MXene incorporation simultaneously enhances proton conductivity and suppresses hydrogen/vanadium crossover. The interaction between MXene functional groups and PFSA's –SO3H reduces the proton diffusion barrier via hydrogen‐bonding networks, while the disordered ...
Panpan Guan, Mingjia Jiang, Yunhu Jiang, Wei Li, Yecheng Zou, Lixiao Zhang, Kaifeng Long, Ziqi Sun, Ting Liao, Hua Kun Liu, Ding Yuan, Dingsheng Wang, Shi Xue Dou, Yuhai Dou   +13 more
wiley   +1 more source

Microdose Cocktail Study Reveals the Activity and Key Influencing Factors of OATP1B, P-Gp, BCRP, and CYP3A in End-Stage Renal Disease Patients. [PDF]

Clin Pharmacol Ther
Kong W, Pan Y, Wu Y, Hu Y, Jiang Z, Tian X, Bi S, Wang S, Feng F, Jin Y, Li J, Li H, Wang Y, Liang H, Tang W, Liu D.   +15 more
europepmc   +1 more source

Thioredoxin‐2 Alleviates Osteoporosis by Restraining FOXO3a Nuclear Translocation

Advanced Science, EarlyView.
Endothelial TRX2 preserves bone homeostasis by retaining FOXO3a at mitochondria and limiting TRAIL production. Loss of TRX2 or oxidative stress releases FOXO3a for nuclear translocation, increasing endothelial TRAIL secretion and driving osteoclast formation and bone loss.
Chi Zhan, Zhaocai Zhou, Yue Ding, Rong Lian, Xinyu Li, Xintong Zhang, Jie Cao, Zhonghui Tang, Zhengmei Lin, Zhi Song, Feng He   +10 more
wiley   +1 more source

Zosuquidar: An Effective Molecule for Intracellular Ca²⁺ Measurement in P-gp Positive Cells. [PDF]

Int J Mol Sci
Pelegrinova L, Sofrankova L, Spaldova J, Stefik P, Sulova Z, Breier A, Elefantova K.   +6 more
europepmc   +1 more source

Persistent Photoluminescence Superlinearity Beyond Static Recombination Physics in Metal Halide Perovskites

Advanced Science, EarlyView.
Persistent intermediate photoluminescence superlinearity in metal halide perovskites challenges the conventional interpretation of β as a fixed recombination‐order indicator. Correlated steady‐state and time‐resolved measurements support a condition‐dependent carrier–lattice relaxation framework, suggesting that β and photoluminescence quantum yield ...
Mehri Ghasemi, Qi Li, Baohua Jia, Xiaoming Wen   +3 more
wiley   +1 more source

Chelidonine overcomes P-gp-mediated adriamycin resistance in MCF-7/ADR cells by inhibiting PDGFR<i>β</i>/PI3K/Akt pathway. [PDF]

Chin Herb Med
Zou X, Zhang Y, Liu K, Zhang L, Li J, Zhang Y, Zhang X, Yu L, Qu Z.   +8 more
europepmc   +1 more source

An AI‐Driven Framework for Directed Self‐Assembly Toward Design‐Technology Co‐Optimization

Advanced Science, EarlyView.
An artificial intelligence (AI)‐driven closed‐loop framework integrates experiment, three‐dimensional physics‐based simulation, and template design for directed self‐assembly (DSA). Guided by experimental data, AI‐assisted calibration accelerates model optimization, supports morphology prediction, and identifies template windows.
Caiwei Shang, Yanting Xu, Yue Zhang, Yan Zhang, Jianfeng Li, Ming Li, Longlin Lei, Wenda Bao, Weixuan Zeng, Shisheng Xiong   +9 more
wiley   +1 more source

Intestinal P-gp activity is reduced in postmenopausal women under breast cancer therapy. [PDF]

Clin Transl Sci
Ximenez JPB, de Andrade JM, Rocha A, Barbosa Coelho E, Suarez-Kurtz G, Lanchote VL.   +5 more
europepmc   +1 more source