We present a complete T2T genome assembly for a key bat reservoir. Integrating population genomics, comparative genomics, transcriptomics, single‐cell omics, and functional assays, we resolve previously inaccessible genomic regions and identify evolutionary signatures associated with immune adaptation.
Yuting Wang +15 more
wiley +1 more source
CeO<sub>2</sub> nanozyme-embedded thermal-deformative polymer for site-specific chemotherapy via HIF-1α-P-gp/lipolysis axis reversal. [PDF]
Tang Z +5 more
europepmc +1 more source
Emerging Memory and Device Technologies for Hardware‐Accelerated Model Training and Inference
This review investigates the suitability of various emerging memory technologies as compute‐in‐memory hardware for artificial intelligence (AI) applications. Distinct requirements for training‐ and inference‐centric computing are discussed, spanning device physics, materials, and system integration.
Yoonho Cho +6 more
wiley +1 more source
Dual Inhibitors of P-gp and Carbonic Anhydrase XII (hCA XII) against Tumor Multidrug Resistance with Piperazine Scaffold. [PDF]
Braconi L +12 more
europepmc +1 more source
A Dual‐Branch Flux‐Based Extended Memristor Model With Machine‐Learning‐Assisted Calibration
Multilayer oxide memristors integrated in crossbar arrays are described through a dual‐branch, flux‐controlled compact model. A three‐stage calibration workflow combining Latin hypercube sampling, Bayesian optimization, and gradient‐based refinement extracts device parameters from experimental data.
Davide Rossetti +6 more
wiley +1 more source
Molecular Mechanisms of Reversal of Multidrug Resistance in Breast Cancer by Inhibition of P-gp by Cytisine N-Isoflavones Derivatives Explored Through Network Pharmacology, Molecular Docking, and Molecular Dynamics. [PDF]
Xiao C, Yin X, Xi R, Yuan C, Ou Y.
europepmc +1 more source
A closed‐loop, data‐driven approach facilitates the exploration of high‐performance Si─Ge─Sn alloys as promising fast‐charging battery anodes. Autonomous electrochemical experimentation using a scanning droplet cell is combined with real‐time optimization to efficiently navigate composition space.
Alexey Sanin +7 more
wiley +1 more source
Corrigendum to Exosomal miRNA confers chemo resistance via targeting Cav1/p-gp/M2-type macrophage axis in ovarian cancer. [PDF]
Kanlikilicer P +19 more
europepmc +1 more source
Patterns of Radiologic Service Utilization and Imaging Expenditure in Supercentenarians in Colombia
Analysis of Colombian administrative health data from 2014 to 2023 identified a distinct pattern of radiologic service utilization among supercentenarians (≥ 110 years). General radiology, ultrasound, and computed tomography were the most frequently used modalities, accounting for most imaging examinations.
Gabriela Puentes +3 more
wiley +1 more source

