Results 21 to 30 of about 3,904,130 (286)

CASSPER is a semantic segmentation-based particle picking algorithm for single-particle cryo-electron microscopy

Communications Biology, 2021
George, Assaiya et al. develop a deep learning tool, CASSPER, that automates the detection of protein particles in transmission microscope images. This algorithm uses semantic segmentation and visually prepared training samples to capture the differences
Blesson George, Anshul Assaiya, Robin J. Roy, Ajit Kembhavi, Radha Chauhan, Geetha Paul, Janesh Kumar, Ninan S. Philip   +7 more
doaj   +1 more source

Allergenic Ribosomal P Proteins [PDF]

Journal of Clinical Microbiology and Biochemical Technology, 2017
Allergenic ribosomal P proteins have been isolated almost exclusively from allergenic mold species with the exception of one from almond.
openaire   +1 more source

Combined Raman Spectroscopy and Digital Holographic Microscopy for Sperm Cell Quality Analysis

Journal of Spectroscopy, 2017
The diagnosis of male infertility is vastly complex. To date, morphology, motility, and concentration have been used as key parameters to establish the sperm normality and achieve pregnancy both in natural and in assisted fecundation.
A. De Angelis, S. Managò, M. A. Ferrara, M. Napolitano, G. Coppola, A. C. De Luca   +5 more
doaj   +1 more source

Fab Fragment of V_HH-Based Antibody Netakimab: Crystal Structure and Modeling Interaction with Cytokine IL-17A

Crystals, 2019
Interleukin 17A (IL-17A) is a proinflammatory cytokine produced by Th17 cells. Antibody BCD-085 (netakimab) against human IL-17A is one of the new inhibitors of this cytokine.
Olga Kostareva, Ilya Kolyadenko, Andrey Ulitin, Victoria Ekimova, Stanislav Evdokimov, Maria Garber, Svetlana Tishchenko, Azat Gabdulkhakov   +7 more
doaj   +1 more source

Passaging of a Newcastle disease virus pigeon variant in chickens results in selection of viruses with mutations in the polymerase complex enhancing virus replication and virulence [PDF]

, 2010
Some Newcastle disease virus (NDV) variants isolated from pigeons (pigeon paramyxovirus type 1; PPMV-1) do not show their full virulence potential for domestic chickens but may become virulent upon spread in these animals.
Dortmans, J.C.F.M., Koch, G., Peeters, B.P.H., Rottier, P.J.M.   +3 more
core   +2 more sources

The selectivity and specificity of autophagy in drosophila [PDF]

, 2012
Autophagy is a process of cellular self-degradation and is a major pathway for elimination of cytoplasmic material by the lysosomes. Autophagy is responsible for the degradation of damaged organelles and protein aggregates and therefore plays a ...
Chou, Clark, Contamine, Deng, Dezelee, Finley, Fouillet, Goto, Kadandale, McPhee, Midorikawa, Nezis, Nisoli, Novak, Orvedahl, Pankiv, Park, Rello-Varona, Schweers, Shoji, Simonsen, Tian, Webb, Wild, Wyers, Yu, Yu, Ziviani   +27 more
core   +2 more sources

New insights into the interplay between long non‐coding RNAs and RNA‐binding proteins in cancer

Cancer Communications, 2022
With the development of proteomics and epigenetics, a large number of RNA‐binding proteins (RBPs) have been discovered in recent years, and the interaction between long non‐coding RNAs (lncRNAs) and RBPs has also received increasing attention.
Zi‐Ting Yao, Yan‐Ming Yang, Miao‐Miao Sun, Yan He, Long Liao, Kui‐Sheng Chen, Bin Li   +6 more
doaj   +1 more source

Label-Free Imaging and Biochemical Characterization of Bovine Sperm Cells

Biosensors, 2015
A full label-free morphological and biochemical characterization is desirable to select spermatozoa during preparation for artificial insemination. In order to study these fundamental parameters, we take advantage of two attractive techniques: digital ...
Maria Antonietta Ferrara, Giuseppe Di Caprio, Stefano Managò, Annalisa De Angelis, Luigi Sirleto, Giuseppe Coppola, Anna Chiara De Luca   +6 more
doaj   +1 more source

Cryo‐Electron Tomography of Toxoplasma gondii Indicates That the Conoid Fiber May Be Derived from Microtubules

Advanced Science, 2023
Toxoplasma gondii (T. gondii) is the causative agent of toxoplasmosis and can infect numerous warm‐blooded animals. An improved understanding of the fine structure of this parasite can help elucidate its replication mechanism.
Zhixun Li, Wenjing Du, Jiong Yang, De‐Hua Lai, Zhao‐Rong Lun, Qiang Guo   +5 more
doaj   +1 more source

Molecular mechanisms of chemo‐ and radiotherapy resistance and the potential implications for cancer treatment

MedComm, 2021
Cancer is a leading cause of death worldwide. Surgery is the primary treatment approach for cancer, but the survival rate is very low due to the rapid progression of the disease and presence of local and distant metastasis at diagnosis.
Ya‐Ping Liu, Can‐Can Zheng, Yun‐Na Huang, Ming‐Liang He, Wen Wen Xu, Bin Li   +5 more
doaj   +1 more source