Results 61 to 70 of about 736,547 (297)

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

Advanced Healthcare Materials, EarlyView.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz, Manuel P. Kainz, Niklas Haider, Theresa Rienmüller, Kerstin Lenk, Rupert Kargl, Michele Terzano, Gerhard Sommer, Gerhard A. Holzapfel, Julia Fuchs   +9 more
wiley   +1 more source

Hydrophilic Polymers Enable Gastrointestinal Transit Monitoring by Fluorine‐19 Magnetic Resonance Imaging

Advanced Healthcare Materials, EarlyView.
Hydrophilic fluorinated copolymers dissolve in chyme and give a strong, single 19F signal, unlike phase‐separating perfluorocarbons. Combined 1H‐19F MRI tracks their whole‐gut transit non‐invasively and without ionizing radiation. In rats, the tracers move through the gastrointestinal tract, resist resorption, and are well tolerated, a proof‐of‐concept
Ondřej Groborz, Vít Herynek, Mária Hovořáková, Zuzana Pavlíková, Linda Dalecká, Klára Steklíková, Petr Matouš, Petr Páral, Margarita Tkachenko, Filip Koucký, Fatma Nalan Cetin, Ludmila Maffei Svobodová, Jiří Beneš, Kristýna Kolouchová   +13 more
wiley   +1 more source

P1 and P2 Purine and Pyrimidine Receptor Ligands

, 2001
Research focused on P1 and P2 purinergic receptor function is currently at a critical stage where considerable efforts in the disciplines of medicinal chemistry, molecular biology, and pharmacology have resulted in the identification of a number of novel ligands that have been used to enhance understanding of the roles of both P1 (adenosine) and P2 ...
Jacobson, K.A., Knutsen, L.J.S.
openaire   +2 more sources

Trions as Fundamental Species in Chemically Doped Polymer Semiconductors

Advanced Materials, EarlyView.
This work shows that exciton–charge carrier coupling in doped polymer semiconductors gives rise to multi‐particle states, including trions—quasiparticles consisting of two holes and one electron under p‐doping—and bound exciton‐hole pairs, as identified through spectroscopic and theoretical analysis.
Hongmo Li, Henry J. Kantrow, David A. Valverde‐Chávez, Meghan McNeil, Arianna Magni, Mohammad Balooch Qarai, Jude Kpare, Jaden Cramlet, Qiao He, Félix Thouin, Zhihao Feng, Yadong Zhang, Andrew Comstock, Stephen Barlow, Jason Azoulay, Seung Soon Jang, Renaud Demadrille, Martin Heeney, Seth Marder, Nicholas J. Hestand, Alberto Salleo, Frank C. Spano, Carlos Silva‐Acuña, Natalie Stingelin   +23 more
wiley   +1 more source

The Membrane-type Collectin CL-P1 Is a Scavenger Receptor on Vascular Endothelial Cells [PDF]

Journal of Biological Chemistry, 2001
Collectins are a family of C-type lectins that have collagen-like sequences and carbohydrate recognition domains (CRD). They are involved in host defense through their ability to bind to carbohydrate antigens of microorganisms. The scavenger receptors type A and MARCO are classical type scavenger receptors that have internal collagen-like domains. Here
Ohtani, Katsuki, Suzuki, Y, Eda, S, Kawai, T, Kase, T, Keshi, H, Sakai, Y, Fukuoh, A, Sakamoto, T, Itabe, H, Suzutani, T, Ogasawara, M, Yoshida, I, Wakamiya, N   +13 more
openaire   +2 more sources

Reversible Hydration Tuning of Polar Order and Large Nonlinear Optical Response in a 2D van der Waals Crystal, LiInP2S6

Advanced Materials, EarlyView.
Hydration‐induced symmetry breaking transforms layered LiInP2S6${\rm LiInP}_2{\rm S}_6$ from a nonpolar to a chiral‐polar phase, producing a giant enhancement of non‐resonant second‐harmonic generation. The reversible tuning of polar order through molecular intercalation establishes a strategy for dynamically controlling nonlinear optical ...
Jadupati Nag, Saugata Sarker, Michael J. Waters, Safdar Imam, Himirkanti Sarkar, Anthony Richardella, James M. Rondinelli, Mercouri G. Kanatzidis, Venkatraman Gopalan   +8 more
wiley   +1 more source

Purine and purinergic receptors

Brain and Neuroscience Advances, 2018
Adenosine 5′-triphosphate acts as an extracellular signalling molecule (purinergic signalling), as well as an intracellular energy source. Adenosine 5′-triphosphate receptors have been cloned and characterised. P1 receptors are selective for adenosine, a
Geoffrey Burnstock
doaj   +1 more source

Tissue-specific 5' heterogeneity of PPARα transcripts and their differential regulation by leptin. [PDF]

PLoS ONE, 2013
The genes encoding nuclear receptors comprise multiple 5'untranslated exons, which give rise to several transcripts encoding the same protein, allowing tissue-specific regulation of expression.
Emma S Garratt, Mark H Vickers, Peter D Gluckman, Mark A Hanson, Graham C Burdge, Karen A Lillycrop   +5 more
doaj   +1 more source

Molecular cloning and functional analysis of scavenger receptor zebrafish CL-P1

Biochimica et Biophysica Acta (BBA) - General Subjects, 2011
Scavenger receptors are generally expressed in macrophages and vascular endothelial cells and some scavenger receptors are thought to contribute to the development of atherosclerosis.We cloned the cDNA of a zebrafish CL-P1 (collectin placenta 1) and performed a knockdown study using its antisense morpholino oligonucleotides (MO).Zebrafish CL-P1 (zCL-P1)
Fukuda, Mitsuko, Ohtani, Katsuki, Jang, Seong-Jae, Yoshizaki, Takayuki, Mori, Ken-ichiro, Motomura, Wataru, Yoshida, Itsuro, Suzuki, Yasuhiko, Kohgo, Yutaka, Wakamiya, Nobutaka   +9 more
openaire   +3 more sources

Asymmetric Lamellar Templating of the Perovskite/C60 Interface for Scalable Inverted Perovskite Photovoltaics

Advanced Materials, EarlyView.
Asymmetric lamellar templating at the perovskite/C60 interface is achieved using a laterally polarized indole spacer. Surface anchoring and Ind–Ind assembly form a π‐rich lamellar interphase that supports uniform C60 contact formation, suppresses recombination, preserves electron extraction, and enables certified high‐efficiency cells and modules with ...
Taeyoon Ki, Jong‐Guk Ahn, Sangcho Kim, Sangjin Kim, Min‐Ho Lee, In‐Wook Hwang, Jinju Jeong, Soobin Shim, Jaeboong Ahn, Jun Hong Park, Seungjin Lee, Jung‐Yong Lee, Yousoo Kim, Ju‐Hyeon Kim, Hongkyu Kang, Sukwon Hong, Kwanghee Lee   +16 more
wiley   +1 more source