Results 71 to 80 of about 736,547 (297)

Scavenger receptor CL-P1 mediates endocytosis by associating with AP-2μ2

Biochimica et Biophysica Acta (BBA) - General Subjects, 2014
Scavenger receptor CL-P1 (collectin placenta 1) has been found recently as a first membrane-type collectin which is mainly expressed in vascular endothelial cells. CL-P1 can endocytose OxLDL as well as microbes but in general, the endocytosis mechanism of a scavenger receptor is not well elucidated.We screened a placental cDNA library using a yeast two-
SeongJae, Jang, Ohtani, Katsuki, Fukuoh, Atsushi, Mori, Kenichiro, Yoshizaki, Takayuki, Kitamoto, Noritoshi, YounUck, Kim, Suzuki, Yasuhiko, Wakamiya, Nobutaka   +8 more
openaire   +4 more sources

Upscaling the Fabrication of Rod‐Shaped Microgels: A Microfluidic Method Combining Step‐Emulsification With Consecutive Droplet Confinement in Parallelized Microchannels

Advanced Materials, EarlyView.
A microfluidic method is presented which enables parallelized fabrication of rod‐shaped microgels, based on step‐emulsification (SE) droplet generation and subsequent droplet distribution and confinement, combined in a single device. Microgel rods are fabricated in parallel at different flow rates based on two light‐mediated crosslinking chemistries ...
Matthias Mork, Ninon Möhl, Greta Romahn, Laura Klasen, Cédric Bergerbit, Laura De Laporte   +5 more
wiley   +1 more source

Effect of bacteriophage P1 lysogeny on lipopolysaccharide composition and the lambda receptor of Escherichia coli [PDF]

Journal of Bacteriology, 1984
The outer membrane of Escherichia coli was altered as a consequence of lysogeny by bacteriophages P1 and P1 cmts. The predominant change was a reduction in the size of lipopolysaccharide to a heptose-deficient form. P1 cmts lysogens were still sensitive to several bacteriophages but were resistant to lambda vir.
J M, Tomás, W W, Kay
openaire   +2 more sources

Mitogenic signaling from P1 and P2 purinergic receptors to mitogen-activated protein kinase in human fetal astrocyte cultures

, 1998
To investigate potential trophic actions of extracellular ATP in human astrocytes, we have examined mitogenic signaling by purinergic receptors in cultures prepared from first trimester rostral central nervous system tissue. We found that ATP and ATP γS,
Micheline McCarthy, Zuniga, Sylvia, Sylvia Zuniga, Yuan Kang, Joseph T Neary, Neary, Joseph T, McCarthy, Micheline, Kang, Yuan   +7 more
core   +1 more source

Dual‐State Programmable Oxide Transistor for Time‐Based Cryptography

Advanced Materials, EarlyView.
A DUPOT enables independently tunable Vth and Isat depending on gate bias polarity, producing three‐dimensional dynamical behavior within a transfer characteristic. This behavior originates from charge trapping and oxygen‐ion migration in the HfO2 layer.
Huisu Noh, Min Gu Lee, Hwayoung Kim, Myeongchan Ko, Jungwan Noh, Taewook Go, Jingyao Yu, Sang‐Hee Ko Park, Himchan Cho, Kyung Min Kim   +9 more
wiley   +1 more source

Smart Antibacterial Coatings: Harnessing Bacterial Redox Activity for Infection Control

Advanced Materials Interfaces, EarlyView.
In this study, we have shown that ceftazidime‐loaded poly(3,4‐ethylenedioxythiophene) (PEDOT@CAZ) functions as a smart, redox‐responsive antibacterial coating that couples bacterial electrical activity with localized antibiotic delivery. Shewanella oneidensis and Pseudomonas aeruginosa induced distinct redox responses in PEDOT, reflecting their ...
Abdullah, Szymon Smołka, Kamran Ayaz, Sara Shakibania, Sajida Maryam, Taral Patel, Roman Turczyn, Ewa Zabłocka‐Godlewska, Katarzyna Krukiewicz   +8 more
wiley   +1 more source

Dual Role of Tamoxifen in Enhancing STING and CEACAM1 Expression to Prime a Favorable Tumor Microenvironment for Anti‐TIM3 Immunotherapy

Advanced Science, EarlyView.
Anti‐PD‐1/PD‐L1 blockade has revolutionized cancer immunotherapy, but is ineffective against endocrine‐treated (i.e., Tamoxifen), relapsed ER+ breast cancer (BC) patients. This study provides insight into the sub‐optimal response of ER+BCs to anti‐PD‐1/PD‐L1 blockade – highlighting the induction of STING and the CEACAM1/TIM3 axis after chronic ...
Marvin Angelo E Aberin, Saurabh Singh, Soumya Chatterjee, Guang‐Zhi Sui, Yi‐Fu Wang, Ya‐Ting Lu, Yu‐Ling Lee, Kun‐Yuan Lin, Joy Khag, Ta‐Yu Liu, Shao‐Han Chang, Wai‐Mui Cheung, Hsiao‐Chin Hong, Ren‐Jun Hsu, Chen‐Yang Shen, Chia‐Wei Li, Weng‐Lang Yang, Yao‐Ming Chang, Shih‐Yu Chen, Chandan Guha, Shu‐Ping Wang   +20 more
wiley   +1 more source

Mating changes the subcellular distribution and the functionality of estrogen receptors in the rat oviduct

Reproductive Biology and Endocrinology, 2009
Background Mating changes the mode of action of 17beta-estradiol (E2) to accelerate oviductal egg transport from a nongenomic to a genomic mode, although in both pathways estrogen receptors (ER) are required.
Sierralta Walter, Rios Mariana, Zuñiga Lidia, Parada-Bustamante Alexis, Orihuela Pedro, Velásquez Luis, Croxatto Horacio   +6 more
doaj  

Purinergic Signalling: Therapeutic Developments

Frontiers in Pharmacology, 2017
Purinergic signalling, i.e., the role of nucleotides as extracellular signalling molecules, was proposed in 1972. However, this concept was not well accepted until the early 1990’s when receptor subtypes for purines and pyrimidines were cloned and ...
Geoffrey Burnstock, Geoffrey Burnstock
doaj   +1 more source

Identification of a domain which affects kinetics and antagonistic potency of clozapine at 5-HT3 receptors. [PDF]

, 2009
The widely used atypical antipsychotic clozapine is a potent competitive antagonist at 5-HT(3) receptors which may contribute to its unique psychopharmacological profile. Clozapine binds to 5-HT(3) receptors of various species.
Gerhard Rammes, Caroline Nothdurfter, Tanasic, S., Rammes, G., Rupprecht, R., Eisensamer, Brigitte, Zieglgänsberger Walter, Christine Hosp, Tanasic, Sascha, Hosp Christine, Walter Zieglgänsberger, Rupprecht Rainer, Rammes, Gerhard, Sascha Tanasic, Hosp, C., Rammes Gerhard, Nothdurfter, C., Tanasic Sascha, Rupprecht, Rainer, Nothdurfter Caroline, Brigitte Eisensamer, Eisensamer, B., Zieglgänsberger, Walter, Zieglgänsberger, W., Hosp, Christine, Rainer Rupprecht, Nothdurfter, Caroline, Eisensamer Brigitte   +27 more
core   +2 more sources