Results 11 to 20 of about 16,178 (230)

P2X receptors [PDF]

open access: yesPhilosophical Transactions of the Royal Society B: Biological Sciences, 2016
Extracellular adenosine 5′-triphosphate (ATP) activates cell surface P2X and P2Y receptors. P2X receptors are membrane ion channels preferably permeable to sodium, potassium and calcium that open within milliseconds of the binding of ATP. In molecular architecture, they form a unique structural family.
openaire   +2 more sources

Emerging key roles for P2X receptors in the kidney [PDF]

open access: yes, 2013
P2X ionotropic non-selective cation channels are expressed throughout the kidney and are activated in a paracrine or autocrine manner following the binding of extracellular ATP and related extracellular nucleotides.
Peppiatt-Wildman, Claire M.   +10 more
core   +1 more source

Offshore Wind Power Integration into Future Power Systems: Overview and Trends

open access: yesJournal of Marine Science and Engineering, 2019
Nowadays, wind is considered as a remarkable renewable energy source to be implemented in power systems. Most wind power plant experiences have been based on onshore installations, as they are considered as a mature technological solution by the ...
Ana Fernández-Guillamón   +3 more
doaj   +1 more source

Inhibitory role of supraspinal P2X3/P2X2/3 subtypes on nociception in rats

open access: yesMolecular Pain, 2006
Extracellular ATP is known to mediate synaptic transmission as a neurotransmitter or a neuromodulator via ionotropic P2X and metabotropic P2Y receptors.
Satoh Masamichi   +4 more
doaj   +1 more source

P2X receptors: epithelial ion channels and regulators of salt and water transport. [PDF]

open access: yes, 2008
When the results from electrophysiological studies of renal epithelial cells are combined with data from in vivo tubule microperfusion experiments and immunohistochemical surveys of the nephron, the accumulated evidence suggests that ATP-gated ion ...
King, Brian F., Wildman, Scott S.P.
core   +1 more source

A P2X receptor from the tardigrade species Hypsibius dujardini with fast kinetics and sensitivity to zinc and copper

open access: yesBMC Evolutionary Biology, 2009
Background Orthologs of the vertebrate ATP gated P2X channels have been identified in Dictyostelium and green algae, demonstrating that the emergence of ionotropic purinergic signalling was an early event in eukaryotic evolution.
Blaxter Mark L   +3 more
doaj   +1 more source

Conditions for profitable operation of P2X energy hubs to meet local demand with energy market access

open access: yesAdvances in Applied Energy, 2023
This paper analyzes the operation of an energy hub on a community level with an integrated P2X facility and with access to energy markets. In our case, P2X allows converting power to hydrogen, heat, methane, or back to power.
Yi Wan   +5 more
doaj   +1 more source

Coexpression of rat P2X2 and P2X6 subunits in Xenopus oocytes. [PDF]

open access: yes, 2000
Transcripts for P2X(2) and P2X(6) subunits are present in rat CNS and frequently colocalize in the same brainstem nuclei. When rat P2X(2) (rP2X(2)) and rat P2X(6) (rP2X(6)) receptors were expressed individually in Xenopus oocytes and studied under ...
B. F. King   +17 more
core   +1 more source

P2X-mediated Ca2+ signalling network developed for this study involved in microglial directed motility.

open access: yes, 2021
The computational model is classified into two parts: (a) fluid compartmental model and (b) microglial membrane electrophysiology. The PMCA (IPMCA) and NCX (in the forward mode) remove cytosolic Ca2+.
Mark Dallas (668437)   +5 more
core   +1 more source

The relationship between P2X4 and P2X7: a physiologically important interaction? [PDF]

open access: yes, 2013
Purinergic signaling within the kidney is becoming an important focus in the study of renal health and disease. The effectors of ATP signaling, the P2Y and P2X receptors, are expressed to varying extents in and along the nephron.
Unwin, RJ   +18 more
core   +1 more source

Home - About - Disclaimer - Privacy