Results 11 to 20 of about 16,178 (230)
Extracellular adenosine 5′-triphosphate (ATP) activates cell surface P2X and P2Y receptors. P2X receptors are membrane ion channels preferably permeable to sodium, potassium and calcium that open within milliseconds of the binding of ATP. In molecular architecture, they form a unique structural family.
openaire +2 more sources
Emerging key roles for P2X receptors in the kidney [PDF]
P2X ionotropic non-selective cation channels are expressed throughout the kidney and are activated in a paracrine or autocrine manner following the binding of extracellular ATP and related extracellular nucleotides.
Peppiatt-Wildman, Claire M. +10 more
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Offshore Wind Power Integration into Future Power Systems: Overview and Trends
Nowadays, wind is considered as a remarkable renewable energy source to be implemented in power systems. Most wind power plant experiences have been based on onshore installations, as they are considered as a mature technological solution by the ...
Ana Fernández-Guillamón +3 more
doaj +1 more source
Inhibitory role of supraspinal P2X3/P2X2/3 subtypes on nociception in rats
Extracellular ATP is known to mediate synaptic transmission as a neurotransmitter or a neuromodulator via ionotropic P2X and metabotropic P2Y receptors.
Satoh Masamichi +4 more
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P2X receptors: epithelial ion channels and regulators of salt and water transport. [PDF]
When the results from electrophysiological studies of renal epithelial cells are combined with data from in vivo tubule microperfusion experiments and immunohistochemical surveys of the nephron, the accumulated evidence suggests that ATP-gated ion ...
King, Brian F., Wildman, Scott S.P.
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Background Orthologs of the vertebrate ATP gated P2X channels have been identified in Dictyostelium and green algae, demonstrating that the emergence of ionotropic purinergic signalling was an early event in eukaryotic evolution.
Blaxter Mark L +3 more
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This paper analyzes the operation of an energy hub on a community level with an integrated P2X facility and with access to energy markets. In our case, P2X allows converting power to hydrogen, heat, methane, or back to power.
Yi Wan +5 more
doaj +1 more source
Coexpression of rat P2X2 and P2X6 subunits in Xenopus oocytes. [PDF]
Transcripts for P2X(2) and P2X(6) subunits are present in rat CNS and frequently colocalize in the same brainstem nuclei. When rat P2X(2) (rP2X(2)) and rat P2X(6) (rP2X(6)) receptors were expressed individually in Xenopus oocytes and studied under ...
B. F. King +17 more
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The computational model is classified into two parts: (a) fluid compartmental model and (b) microglial membrane electrophysiology. The PMCA (IPMCA) and NCX (in the forward mode) remove cytosolic Ca2+.
Mark Dallas (668437) +5 more
core +1 more source
The relationship between P2X4 and P2X7: a physiologically important interaction? [PDF]
Purinergic signaling within the kidney is becoming an important focus in the study of renal health and disease. The effectors of ATP signaling, the P2Y and P2X receptors, are expressed to varying extents in and along the nephron.
Unwin, RJ +18 more
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