Results 91 to 100 of about 1,333,073 (194)

Adenine based acyclic-nucleotides as novel P2X3 receptor ligands

, 2009
A new series of acyclic nucleotides based on the adenine skeleton and bearing in 9-position a phosphorylated four carbon chain has been synthesized. Various substituents were introduced in 2-position of the adenine core.
ANTONINI, Ippolito, SOKOLOVA E, LAMBERTUCCI, Catia, MARUCCI, Gabriella, KACHARE DD, DAL BEN, DIEGO, VITTORI, Sauro, CRISTALLI, Gloria, VOLPINI, Rosaria, NISTRI A, MISHRA RC, Ram Chandra Mishra, Catia Lambertucci, Sauro Vittori, Gloria Cristalli, Gabriella Marucci, Andrea Nistri, Dhuldeo D. Kachare, Diego Dal Ben, Ippolito Antonini, Rosaria Volpini, Elena Sokolova   +21 more
core   +1 more source

Pulsed radiofrequency inhibits expression of P2X3 receptors and alleviates neuropathic pain induced by chronic constriction injury in rats

Chinese Medical Journal, 2019
. Background:. Pulsed radiofrequency (PRF) is a minimally invasive interventional technique that provides a novel and effective treatment strategy for neuropathic pain (NP).
Miao Fu, Lan Meng, Hao Ren, Fang Luo, Yi Cui   +4 more
doaj   +1 more source

Functional crosstalk in culture between macrophages and trigeminal sensory neurons of a mouse genetic model of migraine

BMC Neuroscience, 2012
Background Enhanced activity of trigeminal ganglion neurons is thought to underlie neuronal sensitization facilitating the onset of chronic pain attacks, including migraine.
Franceschini Alessia, Nair Asha, Bele Tanja, van den Maagdenberg Arn MJM, Nistri Andrea, Fabbretti Elsa   +5 more
doaj   +1 more source

Farmakologická charakterizace nových ligandů receptoru P2X3

, 2017
Charles University Faculty of Pharmacy in Hradec Králové Department of pharmacology and toxicology Student: Daulet Balmagambetov Supervisors: Prof. Dr. Christa Elisabeth Müller Dr. Aliaa Abdelrahman Mgr.
Balmagambetov, Daulet
core  

Prostaglandin E2 potentiation of P2X3 receptor mediated currents in dorsal root ganglion neurons-6

, 2011
Copyright information:Taken from "Prostaglandin E2 potentiation of P2X3 receptor mediated currents in dorsal root ganglion neurons"http://www.molecularpain.com/content/3/1/22Molecular Pain 2007;3():22-22.Published online 10 Aug 2007PMCID:PMC2063498.
Guang-Wen Li (81506), Congying Wang (81505), Li-Yen Mae Huang (81507)   +2 more
core   +1 more source

Substituted adenine derivatives as novel P2X3 receptor ligands

, 2010
The purinergic P2X3 subtype is an ATP-gated ion channel mainly expressed in pain sensory neurons and thought to mediate nociception especially in conditions like neuropathic pain and migraine.
GIACOBBE D, LAMBERTUCCI, Catia, MARUCCI, Gabriella, DAL BEN, DIEGO, CRISTALLI, Gloria, VOLPINI, Rosaria, PANMAND DS, NISTRI A   +7 more
core   +1 more source

Electroacupuncture alleviates neuropathic pain in a rat model of CCD via suppressing P2X3 expression in dorsal root ganglia

Chinese Medicine
Background Sciatica and low back pain are prevalent clinical types of neuropathic pain that significantly impair patients' quality of life. Conventional therapies often lack effectiveness, making these conditions challenging to treat. Electroacupuncture (
Yu Zheng, Minjian Jiang, Zhouyuan Wei, Hengyu Chi, Yurong Kang, Siyi Li, Yinmu Zheng, Xiaofen He, Xiaomei Shao, Jianqiao Fang, Yongliang Jiang   +10 more
doaj   +1 more source

Prostaglandin E2 potentiation of P2X3 receptor mediated currents in dorsal root ganglion neurons-0

, 2011
Copyright information:Taken from "Prostaglandin E2 potentiation of P2X3 receptor mediated currents in dorsal root ganglion neurons"http://www.molecularpain.com/content/3/1/22Molecular Pain 2007;3():22-22.Published online 10 Aug 2007PMCID:PMC2063498.
Guang-Wen Li (81506), Congying Wang (81505), Li-Yen Mae Huang (81507)   +2 more
core   +1 more source

The Effects of Two-Week Swimming Training on Neuropathic Pain Induced by Chronic Constriction Injury and the Expression of GAD65 in Adult Male Rats [PDF]

Journal of Fasa University of Medical Sciences, 2016
Background & Objective: Unknown mechanisms are involved in neuropathic pain. Among the non-pharmacological treatments, it seems that physical activity improves neuropathic pain.
Babak Farzad, Hamid Rajabi, Seyed Behnamedin Jameie, Reza Gharakhanlou, Parisa Hayat, Farinaz Nasiri Nejad, Sima Damani   +6 more
doaj   +1 more source

P2X3 receptors and peripheral pain mechanisms

, 2004
ATP released from damaged or inflamed tissues can act at P2X receptors expressed on primary afferent neurones. The resulting depolarization can initiate action potentials that are interpreted centrally as pain.
R. Alan North, North, R. Alan
core   +1 more source