Results 11 to 20 of about 327,693 (283)
p38 MAPK signalling in osteoblast differentiation [PDF]
Frontiers in Cell and Developmental Biology, 2016 The skeleton is a highly dynamic tissue whose structure relies on the balance between bone deposition and resorption. This equilibrium, which depends on osteoblast and osteoclast functions, is controlled by multiple factors that can be modulated post ...
Edgardo eRodríguez-Carballo +2 more
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International Journal of Molecular Sciences, 2021 p38 Mitogen activated protein kinases (p38MAPK) are a highly evolutionary conserved group of protein kinases, which are central for cell adaptation to environmental changes as well as for immune response, inflammation, tissue regeneration, and tumour formation [...]
Juan José Sanz-Ezquerro, Ana Cuenda
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Artificial Cells, Nanomedicine, and Biotechnology, 2019 The objective of this study was to investigate the mechanism underlying miR-21-associated apoptosis in HB. In this study, HB and adjacent tissues were collected from patients with HB.
Lili Liu +6 more
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CXCL12-induced neurotoxicity critically depends on NMDA receptor-gated and L-type Ca2+ channels upstream of p38 MAPK. [PDF]
, 2016 BackgroundThe chemokine receptor CXCR4 (CD184) and its natural ligand CXCL12 contribute to many physiological processes, including decisions about cell death and survival in the central nervous system.
Kaul, Marcus +5 more
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The role of p38 MAPK and its substrates in neuronal plasticity and neurodegenerative disease [PDF]
, 2012 A significant amount of evidence suggests that the p38-mitogen-activated protein kinase (MAPK) signalling cascade plays a crucial role in synaptic plasticity and in neurodegenerative diseases.
Corrêa, Sônia A. L. +1 more
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Effect of Epigallocatechin-3-Gallate on PMA-Induced MUC5B Expression in Human Airway Epithelial Cells [PDF]
Clinical and Experimental Otorhinolaryngology, 2013 ObjectivesAmong the inflammatory mediators, phorbol 12-myristate 13-acetate (PMA) is associated with the regulation of MUC5B expression in the airway epithelial cells. Epigallocatechin-3-gallate (EGCG) is the major component of green tea extract.
Eun Jung Song +6 more
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p38 Mitogen-activated Protein Kinase Regulates Oscillation of Chick Pineal Circadian Clock [PDF]
, 2003 Extracellular signal-regulated kinase (ERK) and p38 are members of the mitogen-activated protein kinase (MAPK) family, and in some cases these kinases serve for closely related cellular functions within a cell. In a wide range of animal clock structures,
Fukada, Yoshitaka +4 more
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European Journal of Cancer Supplements, 2015 The efficiency of endocrine therapy for tumors is limited by the development of hormone resistance and progression of tumor cells to hormone-independent phenotype. Among these tumors – breast cancers, for which hormone therapy is one of the most common and effective methods of treatment, but only in cases, when the tumors retain their hormonal ...
S. Semina, M. Krasil’nikov
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Frontiers in Pharmacology, 2020 Intracerebral hemorrhage (ICH) is a disease with a significantly high rate of morbidity, mortality and disability. Inhibition of inflammation is considered a potential strategy for improving the clinical symptoms induced by ICH.
Lu Zhou +7 more
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Cells, 2023 We have recently reported that in G2-phase cells (but not S-phase cells) sustaining low loads of DNA double-strand break (DSBs), ATM and ATR regulate the G2-checkpoint epistatically, with ATR at the output-node, interfacing with the cell cycle through ...
Daxian Luo +4 more
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