Inhibitors of p38 mitogen-activated protein kinase
Asthma is an inflammatory disease of the airways, which in patients with mild to moderate symptoms is adequately controlled by either beta(2)-adrenoceptor agonists or corticosteroids, or a combination of both. Despite this, there are classes of patients that fail to respond to these treatments.
Robert Newton, Neil Holden
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Mitogen-activated protein kinases mediate Mycobacterium tuberculosis–induced CD44 surface expression in monocytes [PDF]
CD44, an adhesion molecule, has been reported to be a binding site for Mycobacterium tuberculosis (M. tuberculosis) in macrophages and it also mediates mycobacterial phagocytosis, macrophage recruitment and protective immunity against pulmonary ...
Anbalgan, S +2 more
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The Role of p38 MAPK in the Aetiopathogenesis of Psoriasis and Psoriatic Arthritis
The pathogenetic mechanisms responsible for the induction of immune-mediated disorders, such as psoriasis, remain not well characterized. Molecular signaling pathways are not well described in psoriasis, as well as psoriatic arthritis, which is seen in ...
Athanasios Mavropoulos +4 more
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Aging is an inevitable process, which is associated with the development of various diseases such as cardiac hypertrophy. Hypertrophy can occur in both pathological and physiological form.
Behrouz Baghaiee +4 more
doaj
Envolvimento das proteínas quinases ativadas por mitógenos espinhais na lesão medular traumática em ratos [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2011O envolvimento das proteínas quinases ativadas por mitógenos (MAPKs) em lesões do sistema ...
Martini, Alessandra Cadete
core
p38 mitogen-activated protein kinase (p38 MAPK; MAPK14) [PDF]
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p38 Mitogen-Activated Protein Kinase
Kerkela, Risto, Force, Thomas
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Baicalin Suppresses Bilirubin-Induced Apoptosis and Inflammation by Regulating p38 Mitogen-Activated Protein Kinases (MAPK) Signaling in Neonatal Neurons. [PDF]
Shi S +5 more
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The Effects of Arsenite on Mitogen Activated Protein Kinases in Human Keratinocytes
iv, 29 p.The effects of arsenite on several Mitogen Activated Protein Kinases (MAPKs) found in Human Keratinocytes (HACAT) were explored. Western Blot analysis was completed using polyclonal antibodies specific to the phosphorylated & panning c-Jun ...
Diviney, Erin M.
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Cannabinoids activate p38 mitogen-activated protein kinases through CB1 receptors in hippocampus
Cannabinoid receptors (CB1-R) are the target of a novel class of neuromodulators, the endocannabinoids. Yet, their signalling mechanisms in adult brain are poorly understood.
Parmentier, Marc +7 more
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