Results 211 to 220 of about 177,903 (366)

The p38 Mitogen-Activated Protein Kinase Is Required for IL-12-Induced IFN-γ Expression [PDF]

, 2000
Shangming Zhang, Mark H. Kaplan
openalex   +1 more source

Targeting Regulation of Macrophage to Treat Metabolic Disease: Role of Phytochemicals

Cell Proliferation, EarlyView.
One‐third of the world's population is affected by metabolic syndrome. Complicated pathogenesis and limited drugs cause the growing prevalence of metabolic syndrome. Macrophage‐mediated metaflammation is closely associated with the development of metabolic syndrome. The role of phytochemicals targeting macrophages in the treatment of metabolic syndrome
Zeting Ye, Yanlin Li, Xiaolin Yang, Chenglin Li, Rui Yu, Guangjuan Zheng, Zuqing Su   +6 more
wiley   +1 more source

Activation of p38 Mitogen-Activated Protein Kinase In Vivo Selectively Induces Apoptosis of CD8⁺ but Not CD4⁺ T Cells [PDF]

, 2000
Chris Merritt, Hervé Enslen, Nicole L. Diehl, Dietrich B. Conze, Roger J. Davis, Mercedes Rincón   +5 more
openalex   +1 more source

IMPDH2's Central Role in Cellular Growth and Diseases: A Potential Therapeutic Target

Cell Proliferation, EarlyView.
IMPDH2 is a rate‐limiting enzyme in guanine nucleotide biosynthesis. It plays diverse roles in various physiological and pathological processes: nucleotide metabolism, inflammation, immune function, ribosomal stress. Structural or regulatory alterations in IMPDH2 are linked to significant health issues, and critical relevance in disease progression. We
Zheng Li, Yunpeng Zou, Jiayao Niu, Ying Zhang, Aohua Yang, Wenyu Lin, Jie Guo, Shuya Wang, Ronghan Liu   +8 more
wiley   +1 more source

Opposing Role of Mitogen-activated Protein Kinase Subtypes, Erk-1/2 and p38, in the Regulation of Chondrogenesis of Mesenchymes [PDF]

, 2000
Chun‐do Oh, Sung-Hee Chang, Young-Mee Yoon, Su‐Jae Lee, Yun‐Sil Lee, Shin-Sung Kang, Jang-Soo Chun   +6 more
openalex   +1 more source

Cannabinoids activate p38 mitogen‐activated protein kinases through CB1 receptors in hippocampus

Journal of Neurochemistry, 2001
P. Derkinderen, C. Ledent, M. Parmentier, J. Girault   +3 more
semanticscholar   +1 more source

Stress and Vascular Responses: Atheroprotective Effect of Laminar Fluid Shear Stress in Endothelial Cells: Possible Role of Mitogen-Activated Protein Kinases

Journal of Pharmacological Sciences, 2003
Atherosclerosis preferentially occurs in areas of turbulent blood flow and low fluid shear stress, whereas laminar blood flow and high shear stress are atheroprotective.
Masanori Yoshizumi, Jun-ichi Abe, Koichiro Tsuchiya, Bradford C. Berk, Toshiaki Tamaki   +4 more
doaj  

Intermittent Fasting‐Induced Orm2 Promotes Adipose Browning via the GP130/IL23R‐p38 Cascade

Advanced Science
Intermittent fasting (IF) plays a critical role in mitigating obesity, yet the precise biological mechanisms require further elucidation. Here Orosomucoid 2 (Orm2) is identified as an IF‐induced hepatokine that stimulates adipose browning.
Xuejuan Zhu, Xinran Wang, Jingang Wang, Lei Du, Zhen‐Ning Zhang, Donglei Zhou, Junfeng Han, Bing Luan   +7 more
doaj   +1 more source

Roles of JNK, p38 and ERK mitogen-activated protein kinases in the growth inhibition and apoptosis induced by cadmium [PDF]

, 2000
Show‐Mei Chuang, I‐Ching Wang, Jia‐Ling Yang   +2 more
openalex   +1 more source

The Mitogen-Activated Protein Kinase (MAPK)-Activated Protein Kinases MK2 and MK3 Cooperate in Stimulation of Tumor Necrosis Factor Biosynthesis and Stabilization of p38 MAPK

Molecular and Cellular Biology, 2006
Natalia Ronkina, A. Kotlyarov, O. Dittrich‐Breiholz, M. Kracht, E. Hitti, K. Milarski, R. Askew, S. Marušić, Lih-Ling Lin, M. Gaestel, J. Telliez   +10 more
semanticscholar   +1 more source