Results 81 to 90 of about 14,891 (243)

Arterial–venous differences of brain‐derived neurotrophic factor isoforms across the brain and muscle after exercise at different intensities

The Journal of Physiology, EarlyView.
Abstract figure legend Exercise‐induced increases in forearm venous plasma and serum brain‐derived neurotrophic factor (BDNF) are often assumed to be indicative of release from the brain. Sixteen healthy and physically fit adults (20–40 years old) were recruited to investigate whether exercise‐induced changes in forearm venous mature BDNF (mBDNF) and ...
Olga Tarassova, Yiwen Jiang, Helena Wallin, Mats Jensen‐Urstad, Nikola Drca, Julia Röja, Marjan Pontén, Abram Katz, Jonna Nilsson, Maria M. Ekblom, Marcus Moberg   +10 more
wiley   +1 more source

Generation of mice with a conditional allele for the p75 NTR neurotrophin receptor gene [PDF]

, 2011
The p75 NTR neurotrophin receptor has been implicated in multiple biological and pathological processes. While significant advances have recently been made in understanding the physiologic role of p75 NTR , many details and aspects remain to be ...
Bogenmann, Emil, Kaartinen, Vesa M., Kim, Jieun, Li, Qianfeng, Pierchala, Brian, Thomas, Penny S., Yang, Liang‐tung   +6 more
core   +1 more source

Common olfactory ensheathing glial markers in the developing human olfactory system [PDF]

, 2016
The in situ immunocytochemical properties of olfactory ensheathing cells (OECs) have been well studied in several small to medium sized animal models including rats, mice, guinea pigs, cats and canines.
Choi, D, Cotfas, D, Oprych, K
core   +1 more source

Genetic Risk Factors for Poor Cognitive Outcome Following Brain Insult—A Systematic Review

Brain and Behavior, Volume 16, Issue 1, January 2026.
This systematic review summarizes genetic predictors of cognitive outcomes following stroke, traumatic brain injury, and other brain insults. APOE‐ε4 consistently predicts poorer cognitive recovery. Evidence for the COMT rs4680 G allele suggests adverse associations, while BDNF findings remain inconsistent.
Tora Dunås, Sophia Leiss, Alba Corell, Thomas Skoglund, Anna Dénes, Helena Carén, Anja Smits, Isabelle Rydén, Asgeir Jakola   +8 more
wiley   +1 more source

Der Neurotrophinrezeptor p75NTR

, 2002
0 Titelblatt 1 1 Zusammenfassung 9 2 Abstract 10 3 Einleitung 11 3.1 Biologische Funktion der Neurotrophine 11 3.2 Struktur der Neurotrophine 13 3.3 Die Rezeptoren der Neurotrophine 14 3.3.1 Die Trk Rezeptoren 15 3.3.2 Der Neurotrophinrezeptor p75NTR 16 4 Zielsetzung der Arbeit 21 4.1 Reinigung von intrazellulären Interaktoren 21 4.1.1 Experimentelle ...
openaire   +2 more sources

Detection of p75NTR Trimers: Implications for Receptor Stoichiometry and Activation [PDF]

Journal of Neuroscience, 2015
The p75 neurotrophin receptor (p75(NTR)) is a multifunctional receptor that participates in many critical processes in the nervous system, ranging from apoptosis to synaptic plasticity and morphological events. It is a member of the tumor necrosis factor receptor (TNFR) superfamily, whose members undergo trimeric oligomerization. Interestingly, p75(NTR)
Anastasia Gonzalez, Agustin, Barker, Phillip A., Chao, Moses V., Hempstead, Barbara L.   +3 more
openaire   +3 more sources

Ablation of p75NTR signaling strengthens gamma–theta rhythm interaction and counteracts Aβ-induced degradation of neuronal dynamics in mouse hippocampus in vitro

Translational Psychiatry, 2021
Gamma and theta brain rhythms play important roles in cognition and their interaction can affect gamma oscillation features. Hippocampal theta oscillations depend on cholinergic and GABAergic input from the medial septum-diagonal band of Broca.
Yuniesky Andrade-Talavera, Hugo Balleza-Tapia, Pablo Dolz-Gaitón, Gefei Chen, Jan Johansson, André Fisahn   +5 more
doaj   +1 more source

The role of p75NTR in cholinergic basal forebrain structure and function [PDF]

, 2014
The role of the p75 neurotrophin receptor (p75NTR) in adult cholinergic basal forebrain (cBF) neurons is unclear due to conflicting results from previous studies and to limitations of existing p75NTR-knock-out mouse models. In the present study we used a
Alfonsi, Fabienne, Boskovic, Zoran, Coulson, Elizabeth J., Fonseka, Sachini, Rumballe, Bree A., Windels, Francois   +5 more
core   +1 more source

Targeted Delivery of Microneurotrophin BNN27 via Biomaterial Grafts Protects Retinal Ganglion Cells After Optic Nerve Injury

Journal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 114, Issue 1, January 2026.
ABSTRACT Emerging neurotrophin treatments for optic nerve injury (ONI) aim to prevent the loss of retinal ganglion cells (RGCs) and enhance axonal regeneration. Microneurotrophins (MNTs), small‐molecule mimetics of neurotrophins, have shown neuroprotective effects in various animal models of neurodegeneration, yet MNT effects on ONI remain unknown ...
K. Georgelou, E. A. Saridaki, C. P. Apostolidou, X. Mallios, A. Papagiannaki, K. Karali, T. Katsila, T. Calogeropoulou, A. Mitraki, D. Karagogeos, I. Charalampopoulos, A. Gravanis, M. Savvaki, D. S. Tzeranis   +13 more
wiley   +1 more source

Zinc inhibits p75NTR-mediated apoptosis in chick neural retina [PDF]

Cell Death & Differentiation, 2001
It has previously been documented that Zn2+ inhibits TrkA-mediated effects of NGF. To evaluate the ability of Zn2+ to attenuate the biological activities of NGF mediated by p75NTR, we characterized the effects of this transition metal cation on both binding and the pro-apoptotic properties of the NGF-p75NTR interaction.
C, Allington, I L, Shamovsky, G M, Ross, R J, Riopelle   +3 more
openaire   +2 more sources