Results 71 to 80 of about 7,025 (177)

Programmed Cell Death in Chronic Rhinosinusitis

open access: yesClinical and Translational Allergy, Volume 16, Issue 6, June 2026.
ABSTRACT Chronic rhinosinusitis (CRS) is a prevalent upper respiratory condition characterized by a multifaceted etiology involving various cellular and molecular processes. In recent years, researchers have increasingly recognized the significance of different forms of programmed cell death (PCD), such as apoptosis and pyroptosis, in the pathological ...
Xingchen Liu   +5 more
wiley   +1 more source

Structure-Function Analysis of the Central Defence Regulator PAD4 in Arabidopsis [PDF]

open access: yes, 2020
In natural and agricultural environments, pathogens and pests reduce plant growth and fitness. To safeguard global food security in light of climate change, breeders need to generate resistant crop varieties that can withstand invasion of pathogens and
Dongus, Joram Andreas
core  

Molecular Basis of Plant Defense Against Aphids: Role of the Arabidopsis Thaliana PAD4 and MPL1 Genes [PDF]

open access: yes, 2011
Myzus persicae (Sülzer), commonly known as green peach aphid (GPA), utilizes its slender stylet to penetrate the plant tissues intercellularly and consume copious amounts of photoassimilates present in the phloem sap causing extensive damage to host ...
Joe Louis, Louis, Joe
core   +1 more source

The Role of Neutrophils and NETosis in Diseases: The Implications for Therapy

open access: yesMedComm, Volume 7, Issue 6, June 2026.
Neutrophils secrete cytokines, express specific surface proteins, increase or decrease in cell count, and their ratio to lymphocyte count can be used as biomarkers to characterize collective status and disease progression. Neutrophils can monitor and track the body's health status, “Wei Bing” status, disease status, and different times of disease ...
Zhen Ma   +6 more
wiley   +1 more source

Oxidative Stress in the Tumor Immune Microenvironment: Mechanisms and Therapeutic Perspectives

open access: yesMedComm – Oncology, Volume 5, Issue 2, June 2026.
Oxidative stress is involved in several key processes in cancer, including redox regulation, DNA damage, post‐translational modifications, transcriptional regulation, epigenetic modifications, metabolic reprogramming, cell death, and immune modulation. These mechanisms collectively influence tumor progression, immune evasion, and therapeutic responses,
Zhen Wang   +14 more
wiley   +1 more source

Advancements in Inorganic Chiral Nanomaterials for Anti‐Tumor Immunotherapy

open access: yesCancer Science, Volume 117, Issue 6, Page 1543-1553, June 2026.
Schematic illustration of how inorganic chiral nanomaterials enhance immune activation to promote tumor cell elimination through targeted delivery, immunogenic cell death, and immune microenvironment modulation. ABSTRACT While the past decade has witnessed unprecedented technological advancements, cancer remains a major health threat, with conventional
Siyu Chen   +9 more
wiley   +1 more source

Localization and expression of peptidylarginine deiminase 4 (PAD4) in mammalian oocytes and preimplantation embryos

open access: yes, 2011
SummaryPost-translational modifications generally involve the addition or removal of various functional groups to or from the protein residues. However, citrullination, which is catalyzed by the peptidylarginine deiminases (PADs), involves conversion of ...
Manjula Brahmajosyula, Masashi Miyake
core   +1 more source

ESCRT: A Cellular Nexus of Plant Immunity and Pathogen Counter‐Strategies

open access: yesMolecular Plant Pathology, Volume 27, Issue 6, June 2026.
The endosomal sorting complex required for transport (ESCRT) plays multifaceted roles in plants' responses to pathogens, including regulation of the localization and fate of immune receptors and other related cellular processes. ABSTRACT The endosomal sorting complex required for transport (ESCRT) machinery consists of multiprotein complexes conserved ...
Willam Kyle Sexton, Shunyuan Xiao
wiley   +1 more source

VqLecRKV.4 and VqBAK1 Modulate Grapevine Resistance to Powdery Mildew by Regulating Dynamic Balance of ROS

open access: yesPlant Biotechnology Journal, Volume 24, Issue 6, Page 3691-3707, June 2026.
ABSTRACT Grapevine powdery mildew, caused by the fungal pathogen Erysiphe necator, severely impacts plant growth and berry quality. However, the grapevine receptors and molecular mechanisms underlying grapevine resistance to E. necator remain poorly understood.
Yajuan Li   +9 more
wiley   +1 more source

Analysing Novel Structures of Protein Complexes Requiring the Central Plant Immune Regulator EDS1

open access: yes, 2013
Plants as sessile organisms are constantly attacked by pathogens and have evolved a complex immune system to cope with this challenge. The first inducible layer of plant immunity recognises pathogens outside each plant cell and activates a resistance ...
Wagner, Stephan
core  

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