Results 71 to 80 of about 7,025 (177)
Programmed Cell Death in Chronic Rhinosinusitis
ABSTRACT Chronic rhinosinusitis (CRS) is a prevalent upper respiratory condition characterized by a multifaceted etiology involving various cellular and molecular processes. In recent years, researchers have increasingly recognized the significance of different forms of programmed cell death (PCD), such as apoptosis and pyroptosis, in the pathological ...
Xingchen Liu +5 more
wiley +1 more source
Structure-Function Analysis of the Central Defence Regulator PAD4 in Arabidopsis [PDF]
In natural and agricultural environments, pathogens and pests reduce plant growth and fitness. To safeguard global food security in light of climate change, breeders need to generate resistant crop varieties that can withstand invasion of pathogens and
Dongus, Joram Andreas
core
Molecular Basis of Plant Defense Against Aphids: Role of the Arabidopsis Thaliana PAD4 and MPL1 Genes [PDF]
Myzus persicae (Sülzer), commonly known as green peach aphid (GPA), utilizes its slender stylet to penetrate the plant tissues intercellularly and consume copious amounts of photoassimilates present in the phloem sap causing extensive damage to host ...
Joe Louis, Louis, Joe
core +1 more source
The Role of Neutrophils and NETosis in Diseases: The Implications for Therapy
Neutrophils secrete cytokines, express specific surface proteins, increase or decrease in cell count, and their ratio to lymphocyte count can be used as biomarkers to characterize collective status and disease progression. Neutrophils can monitor and track the body's health status, “Wei Bing” status, disease status, and different times of disease ...
Zhen Ma +6 more
wiley +1 more source
Oxidative Stress in the Tumor Immune Microenvironment: Mechanisms and Therapeutic Perspectives
Oxidative stress is involved in several key processes in cancer, including redox regulation, DNA damage, post‐translational modifications, transcriptional regulation, epigenetic modifications, metabolic reprogramming, cell death, and immune modulation. These mechanisms collectively influence tumor progression, immune evasion, and therapeutic responses,
Zhen Wang +14 more
wiley +1 more source
Advancements in Inorganic Chiral Nanomaterials for Anti‐Tumor Immunotherapy
Schematic illustration of how inorganic chiral nanomaterials enhance immune activation to promote tumor cell elimination through targeted delivery, immunogenic cell death, and immune microenvironment modulation. ABSTRACT While the past decade has witnessed unprecedented technological advancements, cancer remains a major health threat, with conventional
Siyu Chen +9 more
wiley +1 more source
SummaryPost-translational modifications generally involve the addition or removal of various functional groups to or from the protein residues. However, citrullination, which is catalyzed by the peptidylarginine deiminases (PADs), involves conversion of ...
Manjula Brahmajosyula, Masashi Miyake
core +1 more source
ESCRT: A Cellular Nexus of Plant Immunity and Pathogen Counter‐Strategies
The endosomal sorting complex required for transport (ESCRT) plays multifaceted roles in plants' responses to pathogens, including regulation of the localization and fate of immune receptors and other related cellular processes. ABSTRACT The endosomal sorting complex required for transport (ESCRT) machinery consists of multiprotein complexes conserved ...
Willam Kyle Sexton, Shunyuan Xiao
wiley +1 more source
ABSTRACT Grapevine powdery mildew, caused by the fungal pathogen Erysiphe necator, severely impacts plant growth and berry quality. However, the grapevine receptors and molecular mechanisms underlying grapevine resistance to E. necator remain poorly understood.
Yajuan Li +9 more
wiley +1 more source
Analysing Novel Structures of Protein Complexes Requiring the Central Plant Immune Regulator EDS1
Plants as sessile organisms are constantly attacked by pathogens and have evolved a complex immune system to cope with this challenge. The first inducible layer of plant immunity recognises pathogens outside each plant cell and activates a resistance ...
Wagner, Stephan
core

