Results 131 to 140 of about 5,442 (184)
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Design considerations for PAMAM dendrimer therapeutics
Bioorganic & Medicinal Chemistry Letters, 2013We have previously shown that methotrexate (MTX) conjugated to a cancer-specific poly amido amine (PAMAM) dendrimer has a higher therapeutic index than MTX alone. Unfortunately, these therapeutics have been difficult to advance because of the complicated syntheses and an incomplete understanding of the dendrimer properties.
Sascha N, Goonewardena +7 more
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Journal of Biomaterials Science, Polymer Edition, 2015
Achieving biomimetic mineralization of collagen fibrils by mimicking the role of non-collagenous proteins (NCPs) with biomimetic analogs is of great interest in the fields of material science and stomatology. Amine-terminated PAMAM dendrimer (PAMAM-NH2), which possesses a highly ordered architecture and many calcium coordination sites, may be a ...
Kunneng, Liang +6 more
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Achieving biomimetic mineralization of collagen fibrils by mimicking the role of non-collagenous proteins (NCPs) with biomimetic analogs is of great interest in the fields of material science and stomatology. Amine-terminated PAMAM dendrimer (PAMAM-NH2), which possesses a highly ordered architecture and many calcium coordination sites, may be a ...
Kunneng, Liang +6 more
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Self‐assembled PAMAM dendrimer films
Advanced Materials, 1997Self‐assembly of starburst dendrimers into closely packed cells (see the optical micrograph in the Figure) is reported for generation 9.5 polyamidoamine (PAMAM) dendrimers solvent‐cast onto hydrophilic silicon substrates. It is shown that on the microscopic scale the cells are made up of a complex network of intertwined dendritic microfibrils ...
Simon A. Evenson, Jas Pal S. Badyal
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Incorporation of fluorescent probes into PAMAM dendrimers
Bioelectrochemistry, 2004Interactions of two fluorescent probes 1-(trimethylammoniumphenyl)-6-phenyl-1,3,5 hexatriene p-toluenesulfonate (TMA-DPH) and 12-(9-anthroyloxy) stearic acid (12-AS) with polyamidoamine (PAMAM) dendrimers were studied. Changes in fluorescence intensity and steady-state fluorescence anisotropy of TMA-DPH and 12-AS were monitored. It was found that 12-AS
D M, Domański +2 more
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2005
(MW ) (high loading beads;1 single bead analysis;2, 3 water compatible, synthesis of peptides;1-3 dendrimer-chlorambucil conjugate;3 aryl ethers;4 amidines-based GP IIb-IIa antagonists;5 benzodiazepinone derivatives;6 diketopiperazine;7 secondary amide;6 biaryl;6 tetrazole;6 site-site interactions.7) Alternate Name: DendroGel.4
Siew-Eng How, Mark Bradley
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(MW ) (high loading beads;1 single bead analysis;2, 3 water compatible, synthesis of peptides;1-3 dendrimer-chlorambucil conjugate;3 aryl ethers;4 amidines-based GP IIb-IIa antagonists;5 benzodiazepinone derivatives;6 diketopiperazine;7 secondary amide;6 biaryl;6 tetrazole;6 site-site interactions.7) Alternate Name: DendroGel.4
Siew-Eng How, Mark Bradley
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CuO nanoparticles with PAMAM dendrimers
Journal of Coordination Chemistry, 2016AbstractAn easy pathway to synthesize a variety of cupric oxide (CuO) nanoshapes by a one-step wet chemical method is reported. CuO nanoparticles and nanorods were obtained from CuCl2 in a mixture of water and DMSO in the absence of a base at room temperature.
A. R. Vázquez-Olmos +4 more
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Self-assembling of DNA and PAMAM dendrimer
2005 IEEE Engineering in Medicine and Biology 27th Annual Conference, 2005The self-assembling of DNA and cationic polymers are of interest for their biological applications. In this paper, the interaction of DNA with PAMAM was studied by agarose gel electrophoresis, size and zeta-potential measurements and circular dichroism (CD) spectroscopy. DNA was shown to form stable complexes with PAMAM by gel electrophoresis. The mean
L Z, Zhou, X L, Yang, L, Gan, H B, Xu
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Fluorescence emission from PAMAM and PPI dendrimers
Journal of Colloid and Interface Science, 2007A strong fluorescence emission from poly(amido amine) (PAMAM) dendrimers with different terminal groups or a poly(propylene imine) (PPI) dendrimer was studied under different conditions by varying experimental parameters such as pH value, aging time, temperature, and concentration.
Dongjun, Wang, Toyoko, Imae, Masao, Miki
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Fluorescence Analysis Of PAMAM Dendrimers
2023Despite their lack of conjugation, polyamidoamine (PAMAM) dendrimers are intrinsically fluorescent, and this fluorescent is somewhat manipulable through altering the dendrimer's solvent. This level of fluorescence is dependent on a number of the dendrimer's qualities: the pH of the solvent, the mass percent concentration of the dendrimer in solvent ...
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Application of PAMAM dendrimers in optical sensing
The Analyst, 2015In this review, recent advances have been reported in those PAMAM dendrimer-based optical sensors that are used for the detection of pH, cations, and other analyte.
E, Soršak +3 more
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