Results 141 to 150 of about 5,442 (184)

Antioxidant Action by Gold−PAMAM Dendrimer Nanocomposites

Langmuir, 2004
Gold-dendrimer nanocomposites were prepared in the presence of poly(amidoamine) (PAMAM) dendrimer (generation 3, 3.5, 5, and 5.5) via reduction of HAuCl4 with sodium borohydride. The average particle size of the gold nanoparticles was independent of the dendrimer concentration, ranging between 3.0 and 4.3 nm in diameter. The catalytic activities of the
Kunio, Esumi, Hiroko, Houdatsu, Tomokazu, Yoshimura   +2 more
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Convergent Synthesis of Internally Branched PAMAM Dendrimers

Organic Letters, 2005
[reaction: see text] A series of aliphatic internally branched poly(amido amine) dendrons and dendrimers has been synthesized. The internal branching unit was 1,2-propanediamine and a series of PAMAM-type dendrons of the types AB2, AB4, and AB8 were built.
Pittelkow, Michael, Christensen, Jørn Bolstad   +1 more
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DNA Assisted Self-Assembly of PAMAM Dendrimers

The Journal of Physical Chemistry B, 2014
We report DNA assisted self-assembly of polyamidoamine (PAMAM) dendrimers using all atom Molecular Dynamics (MD) simulations and present a molecular level picture of a DNA-linked PAMAM dendrimer nanocluster, which was first experimentally reported by Choi et al. (Nano Lett., 2004, 4, 391-397). We have used single stranded DNA (ssDNA) to direct the self-
Mandal, Taraknath, Kumar, Mattaparthi Venkata Satish, Maiti, Prabal K   +2 more
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Nanoscale Protein Pores Modified with PAMAM Dendrimers

Journal of the American Chemical Society, 2007
We describe nanoscale protein pores modified with a single hyperbranched dendrimer molecule inside the channel lumen. Sulfhydryl-reactive polyamido amine (PAMAM) dendrimers of generations 2, 3 and 5 were synthesized, chemically characterized, and reacted with engineered cysteine residues in the transmembrane pore alpha-hemolysin.
Hugh, Martin, Helen, Kinns, Nick, Mitchell, Yann, Astier, Rethi, Madathil, Stefan, Howorka   +5 more
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Toxicity of PAMAM dendrimers to Chlamydomonas reinhardtii

Aquatic Toxicology, 2010
In recent decades, a new class of polymeric materials, PAMAM dendrimers, has attracted marked interest owing to their unique nanoscopic architecture and their hopeful perspectives in nanomedicine and therapeutics. However, the potential release of dendrimers into the aquatic environment raises the issue about their toxicity on aquatic organisms.
Anne-Noëlle, Petit, Philippe, Eullaffroy, Timothée, Debenest, François, Gagné   +3 more
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DNA-Templated Covalent Coupling of G4 PAMAM Dendrimers

Journal of the American Chemical Society, 2010
Generation-4 polyamidoamine (PAMAM) dendrimers were surface-functionalized with azides or alkynes and conjugated to one DNA strand. DNA-controlled self-assembly of alternating azide and alkyne dendrimers on a DNA template enabled the coupling of the dendrimers by the azide-alkyne "click" reaction to form covalently coupled dimers, trimers, and ...
Liu, Huajie, Tørring, Thomas, Dong, Mingdong, Rosen, Christian B, Besenbacher, Flemming, Gothelf, Kurt V   +5 more
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HPLC analysis of PAMAM dendrimer based multifunctional devices

Journal of Chromatography B, 2005
Comprehensive high-performance liquid chromatography (HPLC) analyses were performed on poly(amidoamine) (PAMAM) dendrimer based multifunctional devices. The nanometer-size devices were synthesized by conjugating partially acetylated (Ac) poly(amidoamine) dendrimers of generation 5 (G5) with fluorescein isothiocyanate (FITC), folic acid (FA) and ...
Mohammad T, Islam, Istvan J, Majoros, James R, Baker   +2 more
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Stable hemiaminals attached to PAMAM dendrimers

Tetrahedron Letters, 2009
Abstract Stable hemiaminals (carbinolamines) are formed during the reaction between aromatic aldehydes and amine groups on the surface of polyamidoamino dendrimers in methanol under mild conditions, as monitored by 1 H NMR spectroscopy.
Paweł Subik, Barbara Welc, Beata Wisz, Stanisław Wołowiec   +3 more
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Mechanism of PAMAM Dendrimers Internalization in Hippocampal Neurons

Molecular Pharmaceutics, 2016
Polyamidoamine (PAMAM) dendrimers are hyperbranched macromolecules which have been described as one of the most promising drug nanocarrier systems. A key process to understand is their cellular internalization mechanism because of its direct influence on their intracellular distribution, association with organelles, entry kinetics, and cargo release ...
Felipe, Vidal, Pilar, Vásquez, Carola, Díaz, Daniela, Nova, Joel, Alderete, Leonardo, Guzmán   +5 more
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PAMAM dendrimers: A multifunctional nanomaterial for ECL biosensors

Talanta, 2017
Polyamido amine (PAMAM) dendrimers have been shown to function as electrochemiluminescence (ECL) co-reactant and have the inherent capability of improving immobilization of molecules on surfaces due to their dendritic structure. Here, we investigated the combination of both of these properties as the basis for biosensor development.
Sudeshna, Chandra, Michael, Mayer, Antje J, Baeumner   +2 more
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