Results 161 to 170 of about 19,976 (221)

The Optimal Amount of PAMAM G3 Dendrimer in Polyurethane Matrices Makes Them a Promising Tool for Controlled Drug Release. [PDF]

open access: yesPolymers (Basel)
Zaręba M   +7 more
europepmc   +1 more source

Mononuclear phagocyte-specific cGAS/STING targeting suppresses experimental choroidal neovascularization. [PDF]

open access: yesJCI Insight
Shi L   +10 more
europepmc   +1 more source
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Design considerations for PAMAM dendrimer therapeutics

Bioorganic & Medicinal Chemistry Letters, 2013
We have previously shown that methotrexate (MTX) conjugated to a cancer-specific poly amido amine (PAMAM) dendrimer has a higher therapeutic index than MTX alone. Unfortunately, these therapeutics have been difficult to advance because of the complicated syntheses and an incomplete understanding of the dendrimer properties.
Sascha N, Goonewardena   +7 more
openaire   +2 more sources

Incorporation of fluorescent probes into PAMAM dendrimers

Bioelectrochemistry, 2004
Interactions of two fluorescent probes 1-(trimethylammoniumphenyl)-6-phenyl-1,3,5 hexatriene p-toluenesulfonate (TMA-DPH) and 12-(9-anthroyloxy) stearic acid (12-AS) with polyamidoamine (PAMAM) dendrimers were studied. Changes in fluorescence intensity and steady-state fluorescence anisotropy of TMA-DPH and 12-AS were monitored. It was found that 12-AS
D M, Domański   +2 more
openaire   +2 more sources

Self-assembling of DNA and PAMAM dendrimer

2005 IEEE Engineering in Medicine and Biology 27th Annual Conference, 2005
The self-assembling of DNA and cationic polymers are of interest for their biological applications. In this paper, the interaction of DNA with PAMAM was studied by agarose gel electrophoresis, size and zeta-potential measurements and circular dichroism (CD) spectroscopy. DNA was shown to form stable complexes with PAMAM by gel electrophoresis. The mean
L Z, Zhou, X L, Yang, L, Gan, H B, Xu
openaire   +2 more sources

Application of PAMAM dendrimers in optical sensing

The Analyst, 2015
In this review, recent advances have been reported in those PAMAM dendrimer-based optical sensors that are used for the detection of pH, cations, and other analyte.
E, Soršak   +3 more
openaire   +2 more sources

Toxicity of PAMAM dendrimers to Chlamydomonas reinhardtii

Aquatic Toxicology, 2010
In recent decades, a new class of polymeric materials, PAMAM dendrimers, has attracted marked interest owing to their unique nanoscopic architecture and their hopeful perspectives in nanomedicine and therapeutics. However, the potential release of dendrimers into the aquatic environment raises the issue about their toxicity on aquatic organisms.
Anne-Noëlle, Petit   +3 more
openaire   +2 more sources

PAMAM Dendrimer Resins

2005
(MW ) (high loading beads;1 single bead analysis;2, 3 water compatible, synthesis of peptides;1-3 dendrimer-chlorambucil conjugate;3 aryl ethers;4 amidines-based GP IIb-IIa antagonists;5 benzodiazepinone derivatives;6 diketopiperazine;7 secondary amide;6 biaryl;6 tetrazole;6 site-site interactions.7) Alternate Name: DendroGel.4
Siew-Eng How, Mark Bradley
openaire   +1 more source

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