Results 1 to 10 of about 14,407 (231)

A neutrophil mimicking metal-porphyrin-based nanodevice loaded with porcine pancreatic elastase for cancer therapy [PDF]

Nature Communications, 2023
Xiaogang Qu
exaly   +4 more sources

Studies on porcine pancreatic elastase activity. I. Radioimmuoassay of porcine pancreatic elastase.

The Tohoku Journal of Experimental Medicine, 1980
An improved method of radioimmunoassay was devised to offer a successful formula for determining blood concentration of elastase. With porcine pancreatic elastase as the antigen, rabbits were immunized to obtain antiserum. Iodinated elastase labeled by the chloramine-T procedure using 131I (or 125I) had a specific activity of 200-300 mCi/mg. The double
Y, Nakajima, S, Matsuno, N, Noto, Y, Saitoh, T, Sato   +4 more
openaire   +4 more sources

COMPARISON OF FECAL ELASTASE 1 FOR EXOCRINE PANCREATIC INSUFFICIENCY EVALUATION BETWEEN EX-ALCOHOLICS AND CHRONIC PANCREATITIS PATIENTS [PDF]

Arquivos de Gastroenterologia, 2014
Context Fecal elastase is a noninvasive test for pancreatic insufficiency diagnosis. Objectives Evaluate the usefulness of fecal elastase 1 for the indication of exocrine pancreatic insufficiency among former alcohol addicts and patients with chronic ...
Rejane MATTAR, Gustavo André Silva LIMA, Marianges Zadrozny Gouvêa da COSTA, Joyce M Kinoshita SILVA-ETTO, Dulce GUARITA, Flair José CARRILHO   +5 more
doaj   +2 more sources

Clinical and Analytical Comparison of Monoclonal and Polyclonal Immunoassays for Fecal Pancreatic Elastase [PDF]

Diagnostics
Background: Numerous immunoassays have been commercialized to determine pancreatic elastase (PE) in feces in screening for exocrine pancreatic insufficiency (EPI), but how the different assays compare to one another is controversial, especially in the ...
Jasna Lenicek Krleza, Merica Aralica, Lara Milevoj Kopcinovic, Renata Zrinski Topic   +3 more
doaj   +2 more sources

Shifts in amino acids profile in chronic pancreatitis. [PDF]

PLoS ONE
BackgroundChronic pancreatitis (CP) can lead to pancreatic exocrine insufficiency (PEI), causing protein malabsorption and altered amino acid levels.
Marko Malvik, Kalle Kilk, Raili Müller, Riina Salupere, Mihkel Zilmer, Margus Lember   +5 more
doaj   +2 more sources

Inhibition of pancreatic elastase in silico and in vitro by Rubus rosifolius leaves extract and its constituents

Journal of Pharmacy and Bioallied Sciences, 2020
Objective: Elastases are protease enzymes, which mainly hydrolyze proteins of the connective tissue, so they have a significant impact on human disease.
Yesi Desmiaty, Esti Mulatsari, Fadlina Chany Saputri, Muhammad Hanafi, Rini Prastiwi, Berna Elya   +5 more
doaj   +2 more sources

Enzymatic Cleavage of Stx2a in the Gut and Identification of Pancreatic Elastase and Trypsin as Possible Main Cleavers. [PDF]

Microorganisms, 2023
Kellnerová S, Huber S, Massri M, Fleischer V, Losso K, Sarg B, Kremser L, Talasz H, He X, Varrone E, Brigotti M, Ardissino G, Orth-Höller D, Würzner R.   +13 more
europepmc   +3 more sources

A titratable murine model of progressive emphysema using tracheal porcine pancreatic elastase. [PDF]

Sci Rep, 2023
Joshi I, Devine AJ, Joshi R, Smith NJ, Varisco BM.   +4 more
europepmc   +3 more sources

Detection of human elastase isoforms by the ScheBo Pancreatic Elastase 1 Test. [PDF]

Am J Physiol Gastrointest Liver Physiol, 2017
Determination of fecal pancreatic elastase content by ELISA is a reliable, noninvasive clinical test for assessing exocrine pancreatic function. Despite the widespread use of commercial tests, their exact molecular targets remain poorly characterized.
Tóth AZ, Szabó A, Hegyi E, Hegyi P, Sahin-Tóth M.   +4 more
europepmc   +4 more sources

Fatty pancreas disease in newly diagnosed type 2 diabetes patients: a case–control study on relationships with glycemic control and exocrine function [PDF]

Diabetology & Metabolic Syndrome
Background Fatty pancreas disease (FPD) is characterized by abnormal fat accumulation in pancreatic tissue and is often associated with obesity, metabolic syndrome, and type 2 diabetes mellitus (T2DM).
Tahsin Taner Karaevren, Refika Yorulmaz, Mahinur Cerit, Halit Nahit Şendur, Burak Kalafat, Gizem Yaz Aydın, Özlem Gülbahar, Mehmet Muhittin Yalçın, Ayhan Karakoç, Müjde Aktürk, Füsun Baloş Törüner, Alev Eroğlu Altınova, Taha Enes Çetin, Ethem Turgay Cerit   +13 more
doaj   +2 more sources