Fecal pancreatic elastase-1 levels in older individuals without known gastrointestinal diseases or diabetes mellitus [PDF]
Background Structural changes occur in the pancreas as a part of the natural aging process. With aging, also the incidence of maldigestive symptoms and malnutrition increases, raising the possibility that these might be caused at least in part by ...
Idziak Joanna+6 more
doaj +2 more sources
Background: In the pancreatic cancer can occur pancreatic exocrine insufficiency (PEI) that can be detected by measurement of fecal elastase-1 level. The aim of this study was to identify the proportion and the degree of PEI, proportion of steatorrhea in
Abdul Rahman M+4 more
doaj +3 more sources
Background. Chronic pancreatitis and malnutrition are associated with cardiovascular diseases and cardiovascular events, while the role of exocrine pancreatic insufficiency as a risk factor for cardiovascular events is unknown.
A.Yu. Filippova, V.V. Kryvoshei
doaj +3 more sources
Purification and specificity of pancreatic elastase [PDF]
M. A. Naughton, Frederick Sanger
openaire +4 more sources
Pancreatic endocrine and exocrine function in children following near-total pancreatectomy for diffuse congenital hyperinsulinism. [PDF]
Published onlineJournal ArticleCONTEXT: Congenital hyperinsulinism (CHI), the commonest cause of persistent hypoglycaemia, has two main histological subtypes: diffuse and focal.
Alam, S+6 more
core +3 more sources
Characterization of the S′‐subsite specificity of porcine pancreatic elastase [PDF]
A number of maleyl peptide p‐nitrobenzyl esters have been synthesized to study elastase‐catalyzed hydrolysis reactions. These new substrates were used as acyl donors to investigate the S′‐subsite specificity of porcine pancreatic elastase by partitioning of the acyl enzyme between various added nucleophiles and water.
Volker Schellenberger+3 more
openaire +5 more sources
Enzymatic Cleavage of Stx2a in the Gut and Identification of Pancreatic Elastase and Trypsin as Possible Main Cleavers. [PDF]
Kellnerová S+13 more
europepmc +3 more sources
Fatty pancreas disease in newly diagnosed type 2 diabetes patients: a case-control study on relationships with glycemic control and exocrine function. [PDF]
Background Fatty pancreas disease (FPD) is characterized by abnormal fat accumulation in pancreatic tissue and is often associated with obesity, metabolic syndrome, and type 2 diabetes mellitus (T2DM).
Karaevren TT+13 more
europepmc +2 more sources
Clinical and Analytical Comparison of Monoclonal and Polyclonal Immunoassays for Fecal Pancreatic Elastase. [PDF]
Background: Numerous immunoassays have been commercialized to determine pancreatic elastase (PE) in feces in screening for exocrine pancreatic insufficiency (EPI), but how the different assays compare to one another is controversial, especially in the ...
Lenicek Krleza J+3 more
europepmc +2 more sources
Specificity of a Polyclonal Fecal Elastase ELISA for CELA3. [PDF]
Elastase is a proteolytic pancreatic enzyme that passes through the gastrointestinal tract undergoing only limited degradation. ELISA tests to determine stool elastase concentrations have therefore been developed for the diagnosis of exocrine pancreatic ...
Frank Ulrich Weiss+2 more
doaj +1 more source