Results 11 to 20 of about 439,784 (298)

Detection of human elastase isoforms by the ScheBo Pancreatic Elastase 1 Test. [PDF]

Am J Physiol Gastrointest Liver Physiol, 2017
Determination of fecal pancreatic elastase content by ELISA is a reliable, noninvasive clinical test for assessing exocrine pancreatic function. Despite the widespread use of commercial tests, their exact molecular targets remain poorly characterized.
Tóth AZ, Szabó A, Hegyi E, Hegyi P, Sahin-Tóth M.   +4 more
europepmc   +6 more sources

Fecal pancreatic elastase-1 levels in older individuals without known gastrointestinal diseases or diabetes mellitus [PDF]

BMC Geriatrics, 2011
Background Structural changes occur in the pancreas as a part of the natural aging process. With aging, also the incidence of maldigestive symptoms and malnutrition increases, raising the possibility that these might be caused at least in part by ...
Idziak Joanna, Räsänen Kati M, Purhonen Anna-Kaisa, Herzig Karl-Heinz, Juvonen Petri, Phillps Ryszard, Walkowiak Jaroslaw   +6 more
doaj   +3 more sources

A neutrophil mimicking metal-porphyrin-based nanodevice loaded with porcine pancreatic elastase for cancer therapy. [PDF]

Nat Commun, 2023
Porcine neutrophil elastase (PPE) has been demonstrated to have a histone H1 isoform dependent anti-tumour effect. Here, the authors develop a biomimetic nanoplatform combining PPE and elevated histone H1 release induced by porphyrin nuclear localisation
Cui T, Zhang Y, Qin G, Wei Y, Yang J, Huang Y, Ren J, Qu X.   +7 more
europepmc   +2 more sources

Molecular Elucidation of Pancreatic Elastase Inhibition by Baicalein [PDF]

Journal of Biomolecular Structure and Dynamics, 2020
ABSTRACTThe serine protease, elastase exists in various forms and plays diverse roles in the human body. Pharmacological inhibition of elastase has been investigated for its therapeutic role in managing conditions such as diabetes, pneumonia and arthritis.
Rakesh Joshi, Rakesh Joshi, Debajeet Ghosh, Baban S. Kolte, Baban S. Kolte, Sneha B. Bansode, Rajesh N. Gacche   +6 more
openaire   +6 more sources

Prediction of pancreatic fistula after pancreatoduodenectomy by preoperative dynamic CT and fecal elastase-1 levels. [PDF]

PLoS ONE, 2017
To validate preoperative dynamic CT and fecal elastase-1 level in predicting the development of pancreatic fistulae after pancreatoduodenectomy.For 146 consecutive patients, CT attenuation values of the nontumorous pancreatic parenchyma were ...
Jung-Hyun Kang, Joon Seong Park, Jeong-Sik Yu, Jae-Joon Chung, Joo Hee Kim, Eun-Suk Cho, Dong Sup Yoon   +6 more
doaj   +2 more sources

Difference in the Faecal Elastase-1 Concentration between Resectable and Unresectable Pancreatic Cancer

The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy, 2020
Background: In the pancreatic cancer can occur pancreatic exocrine insufficiency (PEI) that can be detected by measurement of fecal elastase-1 level. The aim of this study was to identify the proportion and the degree of PEI, proportion of steatorrhea in
Abdul Rahman M, Marcellus Simadibrata, Irsan Hasan, Suhendro Suhendro, E Mudjadid   +4 more
doaj   +3 more sources

Pancreatic Elastase Levels in Feces As A Marker of Exocrine Pancreatic Function in Patients With Diabetes Mellitus [PDF]

Laboratoriums Medizin, 2016
OBJECTIVE The measurement of pancreatic elastase (PE) in feces is used widely to screen for pancreatic exocrine insufficiency. The aim of our study was to evaluate the relationship of PE with residual beta cell secretion and metabolic control in patients
R Kangrga, Svetlana Ignjatović, M Dragasević, Snežana Jovičić, Nada Majkić‐Singh   +4 more
openalex   +2 more sources

COMPARISON OF FECAL ELASTASE 1 FOR EXOCRINE PANCREATIC INSUFFICIENCY EVALUATION BETWEEN EX-ALCOHOLICS AND CHRONIC PANCREATITIS PATIENTS

Arquivos de Gastroenterologia, 2014
Context Fecal elastase is a noninvasive test for pancreatic insufficiency diagnosis. Objectives Evaluate the usefulness of fecal elastase 1 for the indication of exocrine pancreatic insufficiency among former alcohol addicts and patients with chronic ...
Rejane MATTAR, Gustavo André Silva LIMA, Marianges Zadrozny Gouvêa da COSTA, Joyce M Kinoshita SILVA-ETTO, Dulce GUARITA, Flair José CARRILHO   +5 more
doaj   +2 more sources

The level of pancreatic fecal elastase-1 and the risk of cardiovascular complications in patients with chronic pancreatitis combined with arterial hypertension

Gastroenterologìa, 2023
Background. Chronic pancreatitis and malnutrition are associated with cardiovascular diseases and cardiovascular events, while the role of exocrine pancreatic insufficiency as a risk factor for cardiovascular events is unknown.
A.Yu. Filippova, V.V. Kryvoshei
doaj   +3 more sources

Fatty pancreas disease in newly diagnosed type 2 diabetes patients: a case–control study on relationships with glycemic control and exocrine function [PDF]

Diabetology & Metabolic Syndrome
Background Fatty pancreas disease (FPD) is characterized by abnormal fat accumulation in pancreatic tissue and is often associated with obesity, metabolic syndrome, and type 2 diabetes mellitus (T2DM).
Tahsin Taner Karaevren, Refika Yorulmaz, Mahinur Cerit, Halit Nahit Şendur, Burak Kalafat, Gizem Yaz Aydın, Özlem Gülbahar, Mehmet Muhittin Yalçın, Ayhan Karakoç, Müjde Aktürk, Füsun Baloş Törüner, Alev Eroğlu Altınova, Taha Enes Çetin, Ethem Turgay Cerit   +13 more
doaj   +2 more sources