Results 21 to 30 of about 14,407 (231)

Impaired exocrine pancreatic function in different stages of type 1 diabetes

BMJ Open Diabetes Research & Care, 2021
Introduction Aim of this study was to investigate the pancreatic exocrine function in patients with type 1 diabetes (T1D) by multiple non-invasive tests.Research design and methods The study is a single-center, cross-sectional study of pancreatic ...
Giulia Martina Cavestro, Emanuele Bosi, Manuela Battaglia, Nicoletta Dozio, Rita Indirli, Gian Maria Giamporcaro, Laura Frosio, Alessandra Mandelli, Andrea Laurenzi, Andrea Mario Bolla, Angela Stabilini, Andrea Valle, Massimo Locatelli, Marina Scavini   +13 more
doaj   +1 more source

EXOCRINE PANCREATIC INSUFFICIENCY IN CHILDREN WITH TYPE 1 DIABETES MELLITUS: A NEW PROBLEM OF PEDIATRIC GASTROENTEROLOGY

Вопросы современной педиатрии, 2013
One of the complications of diabetes mellitus is the development of pancreatic exocrine insufficiency. Fecal elastase 1 is a good marker of pancreatic exocrine secretion.
A. A. Nizhevich, G. M. Yakupova, O. A. Malievskii, E. N. Akhmadeeva, A. M. Farkhutdinova   +4 more
doaj   +1 more source

Assessment of bioelectrical impedance analysis in patients with chronic pancreatitis and chronic obstructive pulmonary disease considering exocrine pancreatic insufficiency

Journal of Education, Health and Sport, 2021
The article describes and analyzes the results of bioelectrical impedance analysis in patients with chronic pancreatitis and chronic obstructive pulmonary disease considering the level of fecal elastase-1.The aim of our study was to investigate the ...
T. Lazaruk, O. Fediv
doaj   +1 more source

The role of the host—Neutrophil biology

Periodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple, Josefine Hirschfeld, Alpdogan Kantarci, Asaf Wilensky, Lior Shapira   +4 more
wiley   +1 more source

Exocrine pancreatic function is preserved in systemic sclerosis

Arthritis Research & Therapy, 2019
Background Systemic sclerosis (SSc) has been suggested to cause exocrine pancreatic dysfunction. However, a case-control-based autopsy study failed to associate systemic sclerosis with any pancreatic histopathology.
Gracijela Bozovic, Rille Pullerits, Arne Ståhl, Kristina Ydström, Daniel Wenger, Jan Marsal, Pontus Thulin, Kristofer Andréasson   +7 more
doaj   +1 more source

Influence of SPK with Enteric Drainage on the Pancreatic Exocrine Function in Diabetic Patients with Uremia

International Journal of Endocrinology, 2017
Objective. This study aimed to determine the use of fecal elastase in evaluating the effect of simultaneous pancreas–kidney transplantation with enteric drainage on the pancreatic exocrine function of diabetic patients with uremia. Methods. A total of 19
Guanghui Pei, Wu Lv, Xiaohang Li, Guoqing Zhang, Jialin Zhang   +4 more
doaj   +1 more source

Fecal pancreatic elastase-1 levels in older individuals without known gastrointestinal diseases or diabetes mellitus

BMC Geriatrics, 2011
Background Structural changes occur in the pancreas as a part of the natural aging process. With aging, also the incidence of maldigestive symptoms and malnutrition increases, raising the possibility that these might be caused at least in part by ...
Idziak Joanna, Räsänen Kati M, Purhonen Anna-Kaisa, Herzig Karl-Heinz, Juvonen Petri, Phillps Ryszard, Walkowiak Jaroslaw   +6 more
doaj   +1 more source

Targeting the Membrane‐Embedded Rhomboid Protease GlpG: A Multimodal Strategy for Inhibitor Discovery and Mechanistic Insight

Angewandte Chemie, EarlyView.
Created in BioRender. Bohg, C. (2026) https://BioRender.Com/ vi9hi4f. Rhomboid proteases are a mechanistically unique and evolutionarily conserved protein family. Despite their pharmacological relevance, the development of selective inhibitors has lagged behind that of soluble proteases.
Claudia Bohg, Yurii Dubanych, Spyridon Kosteletos, Taoran Xiao, Martin Neuenschwander, Tillmann Utesch, Michael Lisurek, Carl Öster, Andreas Oder, Carola Seyffarth, Kathrin Bach, Denise‐Liù Gracias Leone, František Filandr, Marc Wegert, Sascha Lange, Henry Sawczyc, Jens Peter von Kries, Christian P. R. Hackenberger, Edgar Specker, Han Sun, Kvido Stříšovský, Adam Lange   +21 more
wiley   +2 more sources

Remote Pancreatic Response to Severe Polytrauma Correlates With Clinical Outcome. [PDF]

United European Gastroenterol J
ABSTRACT Background Acute pancreatic injury can result from blunt or sharp force trauma, often leading to serious complications. While direct pancreatic trauma is associated with high rates of infection, organ failure, and mortality, little is known about the pancreas as a potential secondary target and remote trauma organ and thereby as a booster of ...
Halbgebauer R, Wohlgemuth L, Wrba J, Braumüller S, Kumral E, Lupu L, Morgenstern C, Bettac L, Wiese S, Mayer B, Cinelli P, Rittirsch D, Pape HC, Roselli F, Seufferlein T, Kleger A, Breunig M, Huber-Lang M.   +17 more
europepmc   +2 more sources

Evaluation of pancreatic elastase-1 measurement during health checkups for detection of pancreatic cancer in asymptomatic individuals

Cancer Treatment and Research Communications
Objectives: Early detection of pancreatic cancer before symptom onset improves curability. This study evaluated the utility of blood elastase-1 as a screening tool for pancreatic cancer in asymptomatic individuals. Methods: A total of 200,583 individuals
Haruka Itoh, Satomi Asai, Shinji Takashimizu, Toshio Nakagohri, Yasuhiro Nishizaki, Hayato Miyachi   +5 more
doaj   +1 more source