Results 21 to 30 of about 439,784 (298)

Clinical and Analytical Comparison of Monoclonal and Polyclonal Immunoassays for Fecal Pancreatic Elastase [PDF]

Diagnostics
Background: Numerous immunoassays have been commercialized to determine pancreatic elastase (PE) in feces in screening for exocrine pancreatic insufficiency (EPI), but how the different assays compare to one another is controversial, especially in the ...
Jasna Lenicek Krleza, Merica Aralica, Lara Milevoj Kopcinovic, Renata Zrinski Topic   +3 more
doaj   +2 more sources

Inhibition of pancreatic elastase in silico and in vitro by Rubus rosifolius leaves extract and its constituents

Journal of Pharmacy and Bioallied Sciences, 2020
Objective: Elastases are protease enzymes, which mainly hydrolyze proteins of the connective tissue, so they have a significant impact on human disease.
Yesi Desmiaty, Esti Mulatsari, Fadlina Chany Saputri, Muhammad Hanafi, Rini Prastiwi, Berna Elya   +5 more
doaj   +2 more sources

The Role of IL-6, 8, and 10, sTNFr, CRP, and Pancreatic Elastase in the Prediction of Systemic Complications in Patients with Acute Pancreatitis

Gastroenterology Research and Practice, 2013
Background and Aim. Early assessment of severity in acute pancreatitis (AP) is a key measure to provide rational and effective management. The aim of our study is to determine the prognostic value of interleukins (IL) 6, 8, and 10, soluble receptor for ...
E. Fisic, G. Poropat, L. Bilic-Zulle, V. Licul, S. Milic, D. Stimac   +5 more
doaj   +2 more sources

Purification and specificity of pancreatic elastase [PDF]

Biochemical Journal, 1961
Michael A. Naughton, Frederick Sanger
openalex   +4 more sources

Enzymatic Cleavage of Stx2a in the Gut and Identification of Pancreatic Elastase and Trypsin as Possible Main Cleavers. [PDF]

Microorganisms, 2023
Kellnerová S, Huber S, Massri M, Fleischer V, Losso K, Sarg B, Kremser L, Talasz H, He X, Varrone E, Brigotti M, Ardissino G, Orth-Höller D, Würzner R.   +13 more
europepmc   +3 more sources

Evaluation of pancreatic elastase-1 measurement during health checkups for detection of pancreatic cancer in asymptomatic individuals

Cancer Treatment and Research Communications
Objectives: Early detection of pancreatic cancer before symptom onset improves curability. This study evaluated the utility of blood elastase-1 as a screening tool for pancreatic cancer in asymptomatic individuals. Methods: A total of 200,583 individuals
Haruka Itoh, Satomi Asai, Shinji Takashimizu, Toshio Nakagohri, Yasuhiro Nishizaki, Hayato Miyachi   +5 more
doaj   +2 more sources

Characterization of the S′‐subsite specificity of porcine pancreatic elastase [PDF]

European Journal of Biochemistry, 1989
A number of maleyl peptide p‐nitrobenzyl esters have been synthesized to study elastase‐catalyzed hydrolysis reactions. These new substrates were used as acyl donors to investigate the S′‐subsite specificity of porcine pancreatic elastase by partitioning of the acyl enzyme between various added nucleophiles and water.
Volker Schellenberger, Ute Schellenberger, Yuri V. Mitin, Hans‐Dieter Jakubke   +3 more
openalex   +5 more sources

Pancreatic endocrine and exocrine function in children following near-total pancreatectomy for diffuse congenital hyperinsulinism. [PDF]

PLoS ONE, 2014
ContextCongenital hyperinsulinism (CHI), the commonest cause of persistent hypoglycaemia, has two main histological subtypes: diffuse and focal. Diffuse CHI, if medically unresponsive, is managed with near-total pancreatectomy.
Ved Bhushan Arya, Senthil Senniappan, Huseyin Demirbilek, Syeda Alam, Sarah E Flanagan, Sian Ellard, Khalid Hussain   +6 more
doaj   +2 more sources

Diagnostic Performance of Measurement of Fecal Elastase-1 in Detection of Exocrine Pancreatic Insufficiency: Systematic Review and Meta-analysis

Clinical Gastroenterology and Hepatology, 2018
Rohini R. Vanga, Aylin Tansel, Saad Sidiq, Hashem B. El‐Serag, Mohamed O. Othman   +4 more
openalex   +3 more sources

Marked difference in efficiency of the digestive enzymes pepsin, trypsin, chymotrypsin, and pancreatic elastase to cleave tightly folded proteins

Biological chemistry, 2021
In order for the intestinal mucosa to absorb dietary proteins they have to be digested into single amino acids or very short peptides of a length of not more than four amino acids.
Zhirong Fu, Srinivas Akula, Michael Thorpe, L. Hellman   +3 more
semanticscholar   +1 more source