Comprehensive sequencing profile and functional analysis of IsomiRs in human pancreatic islets and beta cells. [PDF]
Auddino S +23 more
europepmc +3 more sources
Infusing pancreatic islets into the portal vein currently represents the preferred approach for islet transplantation, despite considerable loss of islet mass almost immediately after implantation.
Zuzana Berkova +10 more
doaj +1 more source
Effect of alcohol on insulin secretion and viability of human pancreatic islets [PDF]
Introduction/Objective. There are controversial data in the literature on the topic of effects of alcohol on insulin secretion, apoptosis, and necrosis of the endocrine and exocrine pancreas. The goal of this research was to determine how alcohol affects
Nikolić Dragan +4 more
doaj +1 more source
Design Principles of Pancreatic Islets: Glucose-dependent Coordination of Hormone Pulses [PDF]
Pancreatic islets are functional units involved in glucose homeostasis. The multicellular system comprises three main cell types; $\beta$ and $\alpha$ cells reciprocally decrease and increase blood glucose by producing insulin and glucagon pulses, while ...
Hara, Manami +2 more
core +9 more sources
This study aimed to ascertain the morphological and morphometric development of pancreatic islets as well as the average levels of numerous hormones during the postnatal development of camel pancreatic islets.
Ahmed Mohamed Rashwan
doaj +1 more source
The pancreatic islet: a micro-organ in control [PDF]
The islets of Langerhans constitute the endocrine pancreas which regulates blood glucose homeostasis and islet dysfunction results in diabetes. Each of the pancreatic islets constitutes an entire micro-organ with intricate cell to cell interactions and ...
M. Abdulreda, P. Berggren
doaj +1 more source
Diabetes mellitus and obesity as a result of a disrupted homeostatic microbiome. New data on etiopathogenesis of diabetes mellitus [PDF]
nema
Nikolić Dragan M.
doaj +1 more source
Long-term cultures of human pancreatic islets in self-assembling peptides hydrogels
Human pancreatic islets transplantation is an experimental therapeutic treatment for Type I Diabetes. Limited islets lifespan in culture remains the main drawback, due to the absence of native extracellular matrix as mechanical support after their ...
Amanda Marchini +9 more
doaj +1 more source
Generation of glucose-responsive functional islets with a three-dimensional structure from mouse fetal pancreatic cells and iPS cells in vitro. [PDF]
Islets of Langerhans are a pancreatic endocrine compartment consisting of insulin-producing β cells together with several other hormone-producing cells. While some insulin-producing cells or immature pancreatic cells have been generated in vitro from ES ...
Hiroki Saito +3 more
doaj +1 more source
Decay score: a guide to the immunoreactivity of human pancreatic islets in autopsy specimen
BACKGROUND: The pancreas is an exo-endocrine organ that undergoes rapid autolysis soon after death, which limits its utility in academics and research.
P. K. Ravi +3 more
doaj +1 more source

