Results 31 to 40 of about 116,954 (354)
PanCircBase: An online resource for the exploration of circular RNAs in pancreatic islets
Frontiers in Cell and Developmental Biology, 2022 Circular RNAs (circRNAs) are a novel class of covalently closed RNA molecules that recently emerged as a critical regulator of gene expression in development and diseases.
Tanvi Sinha +5 more
doaj +1 more source
A Versatile, Portable Intravital Microscopy Platform for Studying Beta-cell Biology In Vivo [PDF]
, 2019 The pancreatic islet is a complex micro-organ containing numerous cell types, including endocrine, immune, and endothelial cells. The communication of these systems is lost upon isolation of the islets, and therefore the pathogenesis of diabetes can only
Conteh, Abass M. +11 more
core +1 more source
miR-375 gene dosage in pancreatic β-cells: implications for regulation of β-cell mass and biomarker development [PDF]
, 2015 MicroRNAs play a crucial role in the regulation of cell growth and differentiation. Mice with genetic deletion of miR-375 exhibit impaired glycemic control due to decreased β-cell and increased α-cell mass and function.
Herrmanns, K +8 more
core +2 more sources
Pancreatic islet transplantation
Seminars in Pediatric Surgery, 2012 Pancreatic islet transplantation is a minimally invasive treatment that has the potential to prevent diabetes after total pancreatectomy for benign disease (islet autotransplantation) and to reverse diabetes in those with type 1 diabetes (islet allotransplantation).
Johnson, P, Jones, K
openaire +2 more sources
Cell Transplantation, 2001 Microencapsulation of pancreatic islets represents a potentially effective method to prevent graft rejection in allotransplantation or xenotransplantation without the need of immunosuppression.
Wenjing Wang +8 more
doaj +1 more source
Journal of Functional Biomaterials, 2023 Recently, tissue engineering, including 3D bioprinting of the pancreas, has acquired clinical significance and has become an outstanding potential method of customized treatment for type 1 diabetes mellitus. The study aimed to evaluate the function of 3D-
Marta Klak +14 more
doaj +1 more source
Dexamethasone during pregnancy impairs maternal pancreatic β-cell renewal during lactation
Endocrine Connections, 2019 Pancreatic islets from pregnant rats develop a transitory increase in the pancreatic β-cell proliferation rate and mass. Increased apoptosis during early lactation contributes to the rapid reversal of those morphological changes.
Caio Jordão Teixeira +5 more
doaj +1 more source
Macrophages in endocrine glands, with emphasis on pancreatic islets [PDF]
, 2016 We review here the macrophages found in endocrine tissues, placing emphasis on those residing in the islets of Langerhans of the pancreas. The islets represent the endocrine organ where macrophages have been examined in great detail and where our own ...
Unanue, Emil R
core +2 more sources
β-cell dysfunctional ERAD/ubiquitin/proteasome system in type 2 diabetes mediated by islet amyloid polypeptide-induced UCH-L1 deficiency. [PDF]
, 2010 ObjectiveThe islet in type 2 diabetes is characterized by β-cell apoptosis, β-cell endoplasmic reticulum stress, and islet amyloid deposits derived from islet amyloid polypeptide (IAPP).
Butler, Alexandra E +7 more
core +2 more sources
Медицинская иммунология, 2023 Insulin-synthesizing cells (ISCs) of pancreatic gland are localized both in its islets, and in exocrine portion, as single cells or cellular agglomerates.
T. S. Bulavintseva +3 more
doaj +1 more source