Results 161 to 170 of about 1,457,192 (230)

Pancreatic Atrophy: A Narrative Review and Surgical Interpretation

Annals of Gastroenterological Surgery, Volume 10, Issue 5, Page 1419-1427, September 2026.
Pancreatic parenchymal atrophy pattern and intraoperative margin assessment guide surgical strategy. ABSTRACT Despite recent advances in multimodal management, pancreatic ductal adenocarcinoma remains a fatal malignancy. Early detection of indirect findings of pancreatic ductal adenocarcinoma is essential to improve treatment outcomes, drawing ...
Rika Fujino, Ken‐ichi Okada, Yohei Masugi, Eisuke Iwasaki, Masaki Mori   +4 more
wiley   +1 more source

A Rare Case of Pancreatic Neuroendocrine Tumor with Intraductal Extension in the Dorsal Duct of a Pancreas Divisum. [PDF]

Reports (MDPI)
Crucillà S, Berlato A, Crinò SF, Landoni L, Conti Bellocchi MC.   +4 more
europepmc   +1 more source

UGT1A1 genotype testing for irinotecan: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

British Journal of Clinical Pharmacology, Volume 92, Issue 9, Page 2986-3001, September 2026.
Abstract Irinotecan, a topoisomerase I inhibitor, is available as both non‐pegylated and pegylated formulations. The non‐pegylated formulation is licensed for use in advanced colorectal cancer either in combination with other agents or as monotherapy.
Dharmisha Chauhan, Cinzia Dello Russo, Jack Thompson, Dyfrig A. Hughes, Katherine Payne, Maria Tsakiroglou, Paul Ross, Rena Chauhan, Simon Jenkinson, Jessica Keen, Sophie Harding, Eleanor Lau, Michael Braun, Roshan Agarwal, Richard Adams, Elisabeth Rolf, Farah Al‐Sheikhli, Sarah Mitchell, Ruth Hammond, Rosie Roberts, Lorna Cairns, Shirley Heggarty, Janet Graham, Justin Mencel, Munir Pirmohamed   +24 more
wiley   +1 more source

GHRH and insulin hypersecretion from a pancreatic neuroendocrine tumor in multiple endocrine neoplasia type 1. [PDF]

JCEM Case Rep
Lamback E, Bulzico DA, Lourenço DM, Vasiljevic A, Raverot G, Gadelha MR.   +5 more
europepmc   +1 more source

Immunological Features of Neuroendocrine Neoplasms and Adrenal Tumors

Cancer Medicine, Volume 15, Issue 9, September 2026.
ABSTRACT Neuroendocrine neoplasms, which occur throughout the human body, as well as adrenocortical carcinoma and pheochromocytoma, which originate in the adrenal gland, are primarily classified as rare malignancies. Immunotherapy, including immune checkpoint inhibitors (ICIs), is generally not incorporated into the standard care protocols for these ...
Akihiro Ohmoto, Shunji Takahashi, Shigehisa Kitano   +2 more
wiley   +1 more source

Mapping metabolic reprogramming dynamics across pancreatic neuroendocrine tumor cell differentiation at single-cell transcriptomic resolution. [PDF]

Front Genet
Yu P, Xiao J.
europepmc   +1 more source

The Molecular and Immunological Landscape in Nasopharyngeal Carcinoma (NPC) Differs by Somatostatin Receptor 2 (SSTR2) Expression

Cancer Medicine, Volume 15, Issue 9, September 2026.
ABSTRACT Somatostatin receptor 2 is expressed in nasopharyngeal carcinoma (NPC). We report genomic and transcriptomic analysis results of 163 NPC cases, demonstrating that somatostatin receptor 2 (SSTR2) gene expression in EBV‐positive and in EBV‐negative NPC correlated with genomic alterations and an inflamed microenvironment.
Dara Bracken‐Clarke, Elisabetta Xue, Harris Krause, Tolulope Adeyelu, Mark G. Evans, Dilara Akbulut, Martha Quezado, Nishant Gandhi, Alex Farrell, Heloisa P. Soares, Emil Lou, Minh Phan, Rusha Patel, Ari M. Vanderwalde, Andrew Elliott, Conor E. Steuer, Nabil F. Saba, Daniel J. Lubin, Nyall R. London Jr, James L. Gulley, Charalampos S. Floudas   +20 more
wiley   +1 more source

Primary Tumor Size and Tumor-Vessel Interface Following Capecitabine and Temozolomide for Pancreatic Neuroendocrine Tumor. [PDF]

Curr Oncol
Guo J, Lewis KA, Prakash L, Bhosale P, Morani A, Katz MHG, Tzeng CD, Ikoma N, Snyder R, Kim MP, Chandrasekharan C, Dasari A, Yao JC, Lee JE, Maxwell JE, Halperin DM.   +15 more
europepmc   +1 more source

Rectal Gastrointestinal Stromal Tumor Poor Response to Imatinib: A Case Report

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT A 63‐year‐old man presented with persistent constipation lasting 6.5 months. Digital rectal examination revealed a soft‐tissue lesion near the anal verge without bleeding. Further evaluation identified a rectal mass. Treatment with imatinib for 6 months showed no significant response. The patient subsequently underwent surgical resection, with
Majid Einakchi, Alireza Samimi, Tooraj Zandbaf, Narges Mesbah   +3 more
wiley   +1 more source

Fatty Acid‐Binding Protein 5 Potentially Regulates the Proliferation and Metastasis of Uveal Melanoma Cells Through the PI3K/AKT/mTOR Signaling Pathway

CNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
Single‐cell and bulk sequencing reveal SPON2, MATK, and FABP5 as prognostic indicators in uveal melanoma. We demonstrated that FABP5 promotes malignancy via the PI3K/AKT/mTOR pathway, as genetic knockdown impairs tumor growth and is rescued by 740Y‐P pharmacological pathway activation. These findings highlight FABP5 maybe as a critical driver of immune
Yue Du, Xue Jiang, Yanyan Zhang, Jianing Ying, Quanyong Yi   +4 more
wiley   +1 more source