Results 101 to 110 of about 5,216 (132)

Biophysical and Pharmacological Characterisations of Pannexin 1

, 2010
The ATP-gated P2X7 receptors (P2X7Rs) play a key role in the release of pro-inflammatory cytokines in response to immunological challenges. Pannexin 1 (Panx1), conventionally described as a hemichannel forming protein, was suggested to be involved in the formation of the P2X7 large pore, which provides a conduit for large molecules such as fluorescent ...
openaire   +1 more source

Pannexin 1 and pannexin 3 differentially regulate the cancer cell properties of cutaneous squamous cell carcinoma. [PDF]

J Physiol
O'Donnell BL, Johnston D, Bhatt A, Kardan Z, Stefan D, Bysice A, Sayedyahossein S, Dagnino L, Cecchini M, Loganathan SK, Roth K, Penuela S.   +11 more
europepmc   +1 more source

Human pannexin 1 channel is not phosphorylated by Src tyrosine kinase at Tyr199 and Tyr309. [PDF]

Elife
Ruan Z, Lee J, Li Y, Du J, Lü W.
europepmc   +1 more source

DAMPs prognostic signature predicts tumor immunotherapy, and identifies immunosuppressive mechanism of pannexin 1 channels in pancreatic ductal adenocarcinoma. [PDF]

Front Immunol
Wu Q, Xiao Q, Tang X, Li L, Song D, Zhou Y, Li B, Ren G, Luo F.   +8 more
europepmc   +1 more source

Hyperactivation of SREBP induces pannexin-1-dependent lytic cell death. [PDF]

J Lipid Res
Xiong Y, Luo J, Hong ZY, Zhu WZ, Hu A, Song BL.   +5 more
europepmc   +1 more source

Poly (I:C)-induced inflammation requires the activation of toll-like receptor 3/Ca²⁺/CaMKII/pannexin 1-dependent signaling. [PDF]

Theranostics
Salgado M, Sepúlveda-Arriagada V, Konar-Nié M, García-Robles MA, Sáez JC.   +4 more
europepmc   +1 more source

Pannexin 1 dysregulation in Duchenne muscular dystrophy and its exacerbation of dystrophic features in mdx mice. [PDF]

Skelet Muscle
Freeman E, Langlois S, Leyba MF, Ammar T, Léger Z, McMillan HJ, Renaud JM, Jasmin BJ, Cowan KN.   +8 more
europepmc   +1 more source

Pannexin-1 channel inhibition alleviates opioid withdrawal in rodents by modulating locus coeruleus to spinal cord circuitry. [PDF]

Nat Commun
Kwok CHT, Harding EK, Burma NE, Markovic T, Massaly N, van den Hoogen NJ, Stokes-Heck S, Gambeta E, Komarek K, Yoon HJ, Navis KE, McAllister BB, Canet-Pons J, Fan C, Dalgarno R, Gorobets E, Papatzimas JW, Zhang Z, Kohro Y, Anderson CL, Thompson RJ, Derksen DJ, Morón JA, Zamponi GW, Trang T.   +24 more
europepmc   +1 more source