Results 91 to 100 of about 3,650 (196)
Stomatin did not alter total or cell surface expression of Panx1.
, 2013 The amount of total and surface Panx1 protein levels were determined with transfected HEK-293 cells expressing either Myc-tagged Panx1 (Panx1::Myc) alone or Panx1::Myc plus HA-tagged stomatin (Stomatin::HA). The bar graphs show the densities of the Panx1:
Zhao-Wen Wang (317498) +9 more
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Pannexin 1 Modulates Axonal Growth in Mouse Peripheral Nerves
Frontiers in Cellular Neuroscience, 2017 The pannexin family of channels consists of three members—pannexin-1 (Panx1), pannexin-2 (Panx2), and pannexin-3 (Panx3) that enable the exchange of metabolites and signaling molecules between intracellular and extracellular compartments.
Steven M. Horton +10 more
doaj +1 more source
Image_3_A Potential Compensatory Role of Panx3 in the VNO of a Panx1 Knock Out Mouse Model.JPEG
, 2018 Pannexins (Panx) are integral membrane proteins, with Panx1 being the best-characterized member of the protein family. Panx1 is implicated in sensory processing, and knockout (KO) animal models have become the primary tool to investigate the role(s) of ...
Stefan Kurtenbach (108906) +5 more
core +1 more source
Frontiers in Pharmacology, 2013 Pannexin1 (Panx1) channels release cytosolic ATP in response to signaling pathways. Panx1 is highly expressed in the central nervous system. We used four antibodies with different Panx1 anti-peptide epitopes to analyze four regions of rat brain.
Angela C Cone +6 more
doaj +1 more source
Frontiers in Cellular Neuroscience, 2017 Pannexin 1 (Panx1) channels are widely recognized for their role in ATP release, and as follows, their function is closely tied to that of ATP-activated P2X7 purinergic receptors (P2X7Rs).
Leigh A. Swayne +2 more
doaj +1 more source
Involuting Panx1-/- mouse mammary glands have normal gland regression.
, 2016 (A) Evaluation of body weight, mammary gland weight and normalized mammary gland weight revealed no significant difference between in Panx1-/- mice compared to control mice.
Dale W. Laird (591712) +3 more
core +1 more source
Pannexin 1 Regulates Bidirectional Hippocampal Synaptic Plasticity in Adult Mice
Frontiers in Cellular Neuroscience, 2014 The threshold for bidirectional modification of synaptic plasticity is known to be controlled by several factors, including the balance between protein phosphorylation and dephosphorylation, postsynaptic free Ca2+ concentration and NMDA receptor (NMDAR ...
Alvaro O. Ardiles +10 more
doaj +1 more source
Image_7_A Potential Compensatory Role of Panx3 in the VNO of a Panx1 Knock Out Mouse Model.jpg
, 2018 Pannexins (Panx) are integral membrane proteins, with Panx1 being the best-characterized member of the protein family. Panx1 is implicated in sensory processing, and knockout (KO) animal models have become the primary tool to investigate the role(s) of ...
Stefan Kurtenbach (108906) +5 more
core +1 more source
Targeting pannexin1 improves seizure outcome.
PLoS ONE, 2011 Imbalance of the excitatory neurotransmitter glutamate and of the inhibitory neurotransmitter GABA is one of several causes of seizures. ATP has also been implicated in epilepsy.
Marcelo F Santiago +7 more
doaj +1 more source
Virgin Panx1-/- mice have normal mammary glands.
, 2016 (A) Evaluation of body weights at 4 and 7 weeks revealed that pre-pubertal Panx1-/- mice were significantly larger at 4 weeks compared to control mice. Values are mean body weights ± S.E.M. * P -/- compared to Panx1+/+ mice. Values are mean weights ± S.E.
Dale W. Laird (591712) +3 more
core +1 more source