BMC Anesthesiology, 2020 Background In the practice of postoperative pain management, pain is still poorly managed in low resource setting where the practice of epidural and opioid free analgesia is impractical.
Zemedu Aweke +3 more
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sGDML: Constructing Accurate and Data Efficient Molecular Force Fields Using Machine Learning [PDF]
, 2019 We present an optimized implementation of the recently proposed symmetric gradient domain machine learning (sGDML) model. The sGDML model is able to faithfully reproduce global potential energy surfaces (PES) for molecules with a few dozen atoms from a ...
Chmiela, Stefan +4 more
core +2 more sources
Investigation of the effect of paracetamol against glutamate-induced cytotoxicity in C6 glia cells
Cumhuriyet Science Journal, 2021 Paracetamol is an active metabolite with analgesic and antipyretic properties of phenacetin, which is sold without a prescription in our country and in many countries.
Kenan Yıldızhan, Murat Doğan
doaj
Paracetamol use in pregnancy: Not as safe as we may think?
Acta Obstetricia et Gynecologica Scandinavica, 2023 Paracetamol is used by more than 50% of women worldwide during pregnancy; headache representing the most frequent indication. Several studies report that long‐term exposure to paracetamol in utero is associated with adverse neurodevelopmental outcomes in
Katinka Nilsen +2 more
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Role of amifostine in preventing liver injury caused by paracetamol intoxication
Medicine ScienceThis investigation attempted to examine the possible protective impact of amifostine, alone or in combination with N-acetylcysteine (NAC), in paracetamol-induced liver injury.
Fatih Turkmen +8 more
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Estimation of paracetamol in urine to assess the diurnal variation
Bangabandhu Sheikh Mujib Medical University Journal, 2018 The aim of the present study was to evaluate the diurnal variation of the pharmacokinetics of paracetamol by estimating the urinary free paracetamol level after single oral administration of paracetamol (500 mg) tablet to 24 healthy male volunteers ...
Mithun Chandro Bhowmik +2 more
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, 2005 BACKGROUND: About 500 drug poisoning deaths involving paracetamol (acetaminophen) occur every year in England and Wales. To reduce the number of deaths, regulations were introduced in 1998 to restrict the sale of paracetamol.
Griffiths, Clare +2 more
core +1 more source
Microbial paracetamol degradation involves a high diversity of novel amidase enzyme candidates
Water Research X, 2022 Pharmaceuticals are relatively new to nature and often not completely removed in wastewater treatment plants (WWTPs). Consequently, these micropollutants end up in water bodies all around the world posing a great environmental risk. One exception to this
Ana B. Rios-Miguel +6 more
doaj +1 more source
Older patients' prescriptions screening in the community pharmacy: development of the Ghent Older People's Prescriptions community Pharmacy Screening (GheOP3S) tool [PDF]
, 2015 Background: Ageing of the population often leads to polypharmacy. Consequently, potentially inappropriate prescribing (PIP) becomes more frequent. Systematic screening for PIP in older patients in primary care could yield a large improvement in health ...
Boussery, Koen +5 more
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Restricting paracetamol in the United Kingdom to reduce poisoning: a systematic review
, 2005 Background Paracetamol poisoning is implicated in about 150-200 poisoning deaths per year in England and Wales. We review previous studies assessing the effectiveness of regulations introduced in 1998 to restrict sales of paracetamol and reduce ...
Majeed, A, Morgan, O
core +1 more source