Results 201 to 210 of about 22,824 (262)

RETRACTION: Molecular Mechanism Whereby Paraoxonase-2 Regulates Coagulation Activation Through Endothelial Tissue Factor in Rat Haemorrhagic Shock Model. [PDF]

Int Wound J
europepmc   +1 more source

Is paraoxonase related to atherosclerosis [PDF]

Chemico-Biological Interactions, 1993
Human serum paraoxonase is responsible for the hydrolysis of organophosphate anticholinesterases, however, whether the enzyme has a physiological role other than the detoxication of insecticides and nerve gases has remained uncertain. Recently, evidence has begun to accumulate of a relationship between the serum activity of paraoxonase and ...
Paul N Durrington, S Arrol, P N Durrington   +2 more
exaly   +9 more sources

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The role of paraoxonase in cancer.

Seminars in Cancer Biology, 2017
The paraoxonase (PON) gene family includes three proteins, PON1, PON2 and PON3. PON1 and PON3 are both associated with high-density lipoprotein (HDL) particles and exert anti-oxidant and anti-inflammatory properties.
T. Bacchetti, G. Ferretti, A. Sahebkar
semanticscholar   +3 more sources

Naphthoquinones, benzoquinones, and anthraquinones: Molecular docking, ADME and inhibition studies on human serum paraoxonase-1 associated with cardiovascular diseases.

Drug development research (Print), 2020
Paraoxonase-1 (PON1) has essential roles such as protecting low-density lipoprotein against detoxification and oxidation of highly toxic compounds. Quinones are a class of compounds and a type of plant-derived secondary metabolites.
Yeliz Demir
semanticscholar   +1 more source

Paraoxonase 1 and atherosclerosis‐related diseases

Biofactors, 2020
A direct and an indirect relationship between paraoxonase 1 (PON1) and atherosclerosis exists. Given PON1's physical location within high‐density lipoprotein (HDL) particles and its recognized enzyme activity, it is certainly reasonable to suggest that ...
J. Kotur-Stevuljević, J. Vekić, A. Stefanović, A. Zeljković, A. Ninić, J. Ivanišević, M. Miljkovic, M. Sopić, J. Munjas, Marija Mihajlović, S. Spasić, Z. Jelić-Ivanović, V. Spasojević-Kalimanovska   +12 more
semanticscholar   +1 more source

Epigenetics of paraoxonases

Current Opinion in Lipidology, 2020
Purpose of review Studies have shown the three-member paraoxonase (PON) multigene family to be involved in the development of a large variety of diseases with an inflammatory component. Environmental factors such as lifestyle-related factors differ widely between populations and it is important to consider that their impacts ...
Abdolkarim, Mahrooz, Mike, Mackness
openaire   +2 more sources

Paraoxonase protects against chlorpyrifos toxicity in mice [PDF]

Toxicology Letters, 1995
Paraoxonase can hydrolyze paraoxon (PO), chlorpyrifos-oxon (CPO) and other organophosphates. Previous studies have indicated that the levels of serum paraoxonase can influence the toxicity of PO and CPO.
Lucio G Costa, Clement Furlong, L G Costa   +2 more
exaly   +1 more source

Genetics of paraoxonase

Annals of Human Genetics, 1981
SUMMARYDanish family material comprising 1664 unrelated individuals (parents) and 3169 children, as well as 699 grandparents of the same families, were examined for paraoxonase activity. A micro‐autoanalyser method, comprising a primary testing in tris buffer at pH 7‐5 and, in the case of primarily intermediate individuals, a secondary testing at pH 10,
H, Eiberg, J, Mohr
openaire   +2 more sources