Results 141 to 150 of about 9,174 (165)

Variation in paraoxonase-1 activity and atherosclerosis

Current Opinion in Lipidology, 2009
Paraoxonase-1 (PON1) is an HDL-associated protein of 354 amino acids with a molecular mass of 43 000 Da. It is synthesized in the liver, and in serum it is almost exclusively associated with HDL. PON1 has been reported to be an important contributor to the antioxidant and anti-inflammatory activities of HDL.
Soran, Handrean, Younis, Nahla N., Charlton-Menys, Valentine, Durrington, Paul   +3 more
openaire   +3 more sources

Systemic Inflammation, Intestine, and Paraoxonase-1

2014
Serum paraoxonase 1 (PON1) has been shown to act as an important guardian against cellular damage from oxidized lipids in low-density lipoprotein (LDL), plasma membrane, against toxic agents such as pesticide residues including organophosphates and against bacterial endotoxin.
Ladan, Vakili, Kaveh Daniel, Navab, Maryam, Shabihkhani, Nasim, Pourtabatabaei, Samra, Vazirian, Zarina, Barseghian, Seyedehsara, Seyedali, Greg, Hough   +7 more
openaire   +2 more sources

Paraoxonase 1: Genetics and Activities During Aging

Rejuvenation Research, 2008
The increasing longevity of the population, one of the most important issues throughout the planet, is a very complex phenomenon (trait), likely resulting from a variety of environmental determinants interacting with and modulated by genetic mechanisms, mostly devoted to maintenance and repair. In fact, the genes involved in longevity impact upon basic
Marchegiani F., Marra M., Olivieri F., Cardelli M., James R. W., Boemi M., FRANCESCHI, CLAUDIO   +6 more
openaire   +3 more sources

Paraoxonase 1 Gene L55M Polymorphism and Paraoxonase 1 Activity in Obstructive Sleep Apnea Patients

2018
The antioxidant enzyme paraoxonase-1 (PON1) may limit oxidative stress in the development of cardiovascular diseases (CVD) and obstructive sleep apnea (OSA). The aim of the study was to determine PON1 gene L55M polymorphism in OSA-positive and OSA-negative subjects, along with paraoxonase activity of the enzyme (PON1-act).
A, Płóciniczak, A, Baszczuk, A, Ludziejewska, H, Winiarska, S, Michalak, G, Kasprzak, D, Formanowicz, S, Cofta, E, Wysocka   +8 more
openaire   +2 more sources

Paraoxonase 1 and Postprandial Lipemia

2008
Risk factors for coronary heart disease (CHD) include decreased insulin sensitivity and glucose intolerance, hypertension, increased body fat mass, unfavorable body fat distribution, the prothrombotic state and dyslipidemia. A clustering of these metabolic disturbances is also seen in Insulin Resistance and the metabolic syndrome.
A. Alipour, B. Coll, A.P. Rietveld, J. Marsillach, J. Camps, J. Joven, J.W.F. Elte, M. Castro Cabezas   +7 more
openaire   +1 more source

Paraoxonase-1 and Cardiovascular Disease

2008
The oxidation of low-density lipoprotein (LDL) in the artery wall is responsible for the initiation and progression of atherosclerosis. High-density lipoprotein (HDL) on the other hand is protective against atherosclerosis development and can attenuate the oxidation of LDL.
B. Mackness, M.I. Mackness
openaire   +1 more source

Misunderstandings about paraoxonase-1

2022
[No Abstract Available]
Mackness, Michael, Sozmen, Eser Y.
openaire   +1 more source

Serum Paraoxonase Activity, Concentration, and Phenotype Distribution in Diabetes Mellitus and Its Relationship to Serum Lipids and Lipoproteins

Arteriosclerosis, Thrombosis, and Vascular Biology, 1995
Paul Durrington, Caroline Abbott, Sudhesh Kumar   +2 more
exaly  

Paraoxonase2 polymorphisms are associated with nephropathy in Type II diabetes

Diabetologia, 2001
Gaillard R C, Ruiz J, R C Gaillard
exaly  

Protection of low-density lipoprotein against oxidative modification by high-density lipoprotein associated paraoxonase

Atherosclerosis, 1993
Paul Durrington, P Durrington, S Arrol   +2 more
exaly