Results 181 to 190 of about 29,702,919 (203)

Paraoxonase 1 and Postprandial Lipemia

2008
Risk factors for coronary heart disease (CHD) include decreased insulin sensitivity and glucose intolerance, hypertension, increased body fat mass, unfavorable body fat distribution, the prothrombotic state and dyslipidemia. A clustering of these metabolic disturbances is also seen in Insulin Resistance and the metabolic syndrome.
A. Alipour, B. Coll, A.P. Rietveld, J. Marsillach, J. Camps, J. Joven, J.W.F. Elte, M. Castro Cabezas   +7 more
openaire   +1 more source

Lead inhibits paraoxonase 2 but not paraoxonase 1 activity in human hepatoma HepG2 cells

Journal of Applied Toxicology, 2012
ABSTRACTLead is an environmental toxicant of great concern for humans and animals. Lead‐induced liver damage and malfunction are partly due to a disturbance of the cellular antioxidant balance. Paraoxonase 1 (PON1) and PON2 are highly expressed in the liver and have been proposed as antioxidative enzymes.
Wanida, Sukketsiri, Sureerut, Porntadavity, Laddawal, Phivthong-ngam, Somsong, Lawanprasert   +3 more
openaire   +2 more sources

Paraoxonase-1 and Cardiovascular Disease

2008
The oxidation of low-density lipoprotein (LDL) in the artery wall is responsible for the initiation and progression of atherosclerosis. High-density lipoprotein (HDL) on the other hand is protective against atherosclerosis development and can attenuate the oxidation of LDL.
B. Mackness, M.I. Mackness
openaire   +1 more source

Misunderstandings about paraoxonase-1

2022
[No Abstract Available]
Mackness, Michael, Sozmen, Eser Y.
openaire   +1 more source

The Role of Paraoxonase 1 in the Detoxification of Homocysteine Thiolactone

2009
The thioester homocysteine (Hcy)-thiolactone, product of an error-editing reaction in protein biosynthesis, forms when Hcy is mistakenly selected by methionyl-tRNA synthetase. Accumulating evidence suggests that Hcy-thiolactone plays an important role in atherothrombosis.
openaire   +2 more sources

Serum Paraoxonase Activity, Concentration, and Phenotype Distribution in Diabetes Mellitus and Its Relationship to Serum Lipids and Lipoproteins

Arteriosclerosis, Thrombosis, and Vascular Biology, 1995
Paul Durrington, Caroline Abbott, Sudhesh Kumar   +2 more
exaly  

Protection of low-density lipoprotein against oxidative modification by high-density lipoprotein associated paraoxonase

Atherosclerosis, 1993
Paul Durrington, P Durrington, S Arrol   +2 more
exaly  

Paraoxonase2 polymorphisms are associated with nephropathy in Type II diabetes

Diabetologia, 2001
R C Gaillard, E Temler
exaly  

Clinical and Genetic Association of Serum Paraoxonase and Arylesterase Activities With Cardiovascular Risk

Arteriosclerosis, Thrombosis, and Vascular Biology, 2012
Stanley Hazen, Hooman Allayee, Jeanette Erdmann   +2 more
exaly  

Is paraoxonase related to atherosclerosis

Chemico-Biological Interactions, 1993
Paul Durrington, S Arrol, Michael I Mackness   +2 more
exaly