Results 21 to 30 of about 406,905 (221)

Cytoarchitecture of the human paraventricular hypothalamic nucleus [PDF]

Medicinski pregled, 2009
Introduction. The significance of this research in terms of structure and biochemical processes in PVN contributes to further understanding of vital physiological processes from delivery and stress to delicate chemical processes that keep the hypothalamo-hypophysial axis in balance. Conclusion.
Babović, Siniša S., Ivanov, Dejan, Mijatov-Ukropina, Ljilja, Toyonaga, Takashi, Dimitrijević, Ivan, Đorđević, Milena   +5 more
openaire   +3 more sources

Hypothalamic Neurochemical and Microglial Suppression in Long-Standing Human Hibernation-Like Syndrome. [PDF]

Neuropathol Appl Neurobiol
A rare case of a human hibernation‐like syndrome was associated with preserved hypothalamic anatomy but profound suppression of neuroendocrine and circadian neuropeptide systems. Marked reductions in synaptic and microglial immunoreactivity suggest a suppressed hypothalamic neuron–glial network, despite preserved astrocytic markers, myelination and ...
Jiang W, Kalsbeek A, Hut RA, Swaab DF, Yi CX.   +4 more
europepmc   +2 more sources

Paraventricular hypothalamic nucleus: Axonal projections to the brainstem [PDF]

Journal of Comparative Neurology, 2010
Abstract The paraventricular hypothalamic nucleus (PVH) contains many neurons that innervate the brainstem, but information regarding their target sites remains incomplete. Here we labeled neurons in the rat PVH with an anterograde axonal tracer, Phaseolus vulgaris ...
Joel C, Geerling, Jung-Won, Shin, Peter C, Chimenti, Arthur D, Loewy   +3 more
openaire   +2 more sources

Oxytocin signaling in the posterior hypothalamus prevents hyperphagic obesity in mice

eLife, 2022
Decades of studies have revealed molecular and neural circuit bases for body weight homeostasis. Neural hormone oxytocin (Oxt) has received attention in this context because it is produced by neurons in the paraventricular hypothalamic nucleus (PVH), a ...
Kengo Inada, Kazoku Tsujimoto, Masahide Yoshida, Katsuhiko Nishimori, Kazunari Miyamichi   +4 more
doaj   +1 more source

Fasting induced cytoplasmic Fto expression in some neurons of rat hypothalamus. [PDF]

PLoS ONE, 2013
Fat mass and obesity associated protein (Fto) is a nucleic acid demethylase, with a preference for thymine or uracil, according to the recent structural data. This fact suggests that methylated single-stranded RNA, rather than DNA, may be the primary Fto
Predrag Vujovic, Stefan Stamenkovic, Nebojsa Jasnic, Iva Lakic, Sinisa F Djurasevic, Gordana Cvijic, Jelena Djordjevic   +6 more
doaj   +1 more source

A secretagogin locus of the mammalian hypothalamus controls stress hormone release [PDF]

, 2015
This work was supported by the Swedish Research Council (T.Ha., T.Hö.), Hjärnfonden (T.Ha.), the Petrus and Augusta Hedlunds Foundation (T.Ha., T.Hö.), the Novo Nordisk Foundation (T.Ha., T.Hö.), Karolinska Institutet (T.Hö.), the Medical University of ...
Marc Landry, Alpár, Alán, Robert Schnell, Botting, Catherine H., André Calas, Shirran, Sally Lorna, Miklós Palkovits, Fuszard, Matthew Alexander, Wagner, Ludwig, Fuszard, Matthew, Zhang, Ming-Dong, Árpád Dobolyi, Jan Mulder, Catherine H Botting, Sten Linnarsson, Tibor Harkany, Lauren Spence, Spence, Lauren, Harkany, Tibor, Sally L Shirran, Matthew Fuszard, Uhlen, Mathias, Hökfelt, Tomas, Landry, Marc, Shirran, Sally L., Martens, Henrik, Amit Zeisel, Mathias Uhlen, Romanov, Roman A., Botting, Catherine Helen, Tomas Hökfelt, Calas, André, Oláh, Márk, Alán Alpár, Harald H Sitte, Linnarsson, Sten, Márk Oláh, Henrik Martens, Roman A Romanov, Schnell, Robert, Ming‐Dong Zhang, Ludwig Wagner, Sitte, Harald H., Uhlén, Mathias,, Dobolyi, Árpád, Zeisel, Amit, Mulder, Jan, Palkovits, Miklós, Fuszard, M, Zhang, M-D, Landry, M, Schnell, R,, Shirran, SL, Dobolyi, A, Romanov, RA, Alpar, A, Zeisel, A,, Calas, A, Shirran, Sally Lorna; id_orcid   +58 more
core   +1 more source

Opioids in the Hypothalamic Paraventricular Nucleus Stimulate Ethanol Intake [PDF]

Alcoholism: Clinical and Experimental Research, 2010
Background: Specialized hypothalamic systems that increase food intake might also increase ethanol intake. To test this possibility, morphine and receptor‐specific opioid agonists were microinjected in the paraventricular nucleus (PVN) of rats that had learned to drink ethanol.
Jessica R, Barson, Ambrose J, Carr, Jennifer E, Soun, Nasim C, Sobhani, Pedro, Rada, Sarah F, Leibowitz, Bartley G, Hoebel   +6 more
openaire   +2 more sources

Glucose in the hypothalamic paraventricular nucleus regulates GLP-1 release [PDF]

, 2020
Glucokinase (GK) is highly expressed in the hypothalamic paraventricular nucleus (PVN); however, its role is currently unknown. We found that GK in the PVN acts as part of a glucose-sensing mechanism within the PVN that regulates glucose homeostasis by ...
Ma, Yue, Gardiner, James, Lam, Bryan, Nguyen-Tu, Marie-sophie, Dhillo, Waljit, Ratnasabapathy, Risheka, Yeo, Giles, Rutter, Guy, Izzi-Engbeaya, Chioma, Cuenco, Joyceline, De Backer, Ivan, Jones, ben, John, christopher   +12 more
core   +2 more sources

Hypothalamic POMC Neurons Gate the Fear-Feeding Trade-Off. [PDF]

Adv Sci (Weinh)
Hungry animals must continually arbitrate between feeding and defensive behaviors when confronted with potential threats. We show that hypothalamic POMC neurons engage CRH‐expressing stress circuits and downstream hormonal responses to coordinate this behavioral selection between competing behaviors.
Miralpeix C, Eraso-Pichot A, Simon V, Jouque V, Sadallah M, Clark S, Zizzari P, Skupio U, Covelo A, Dupuy N, Nicolas JC, Cannich A, Leste-Lasserre T, Laplagne G, Quarta C, Marsicano G, Cota D.   +16 more
europepmc   +2 more sources

Chronic stress plasticity in the hypothalamic paraventricular nucleus [PDF]

, 2008
Proper integration and execution of the physiological stress response is essential for maintaining homoeostasis. Stress responses are controlled in large part by the paraventricular nucleus (PVN) of the hypothalamus, which contains three functionally distinct neural populations that modulate multiple stress effectors: (1) hypophysiotrophic PVN neurons ...
James P, Herman, Jonathan, Flak, Ryan, Jankord   +2 more
openaire   +2 more sources