Scientific Reports, 2017 The paraventricular nucleus of hypothalamus plays important roles in the regulation of energy balance and fetal growth. However, the molecular mechanisms underlying its formation and function have not been clearly elucidated.
Su Feng +12 more
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Depolarizing actions of hydrogen sulfide on hypothalamic paraventricular nucleus neurons. [PDF]
PLoS ONE, 2013 Hydrogen sulfide (H2S) is a novel neurotransmitter that has been shown to influence cardiovascular functions as well and corticotrophin hormone (CRH) secretion.
C Sahara Khademullah +1 more
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Evidence that 5-HT2A Receptors in the Hypothalamic Paraventricular Nucleus Mediate Neuroendocrine Responses to (-)DOI [PDF]
, 2002 This is the publisher's version, also available electronically from "http://www.jneurosci.org".The present study determined whether the serotonin2A (5-HT2A) receptors in the hypothalamic paraventricular nucleus mediate the neuroendocrine responses to a ...
Hanley, Nicole R. Sullivan +13 more
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Frontiers in Neuroscience, 2021 The incidence rate and mortality of hypertension increase every year. Hypothalamic paraventricular nucleus (PVN) plays a critical role on the pathophysiology of hypertension.
Xiao-Jing Yu +9 more
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The hypothalamic paraventricular nucleus may not be at the heart of sympathetic outflow
The Journal of Physiology, 2013 Heart failure (HF) is associated with activation of various neurohumoral factors including the renin–angiotensin–aldosterone and sympathetic nervous systems. In HF patients, elevated sympathetic nerve activity (SNA) is reflected by increased whole body, as well as regional (e.g. cardiac and renal) noradrenaline spillover (Kaye et al. 1994; Petersson et
Sean D, Stocker +2 more
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Melanocortins and agouti-related protein modulate the excitability of two arcuate nucleus neuron populations by alteration of resting potassium conductances [PDF]
, 2007 The hypothalamic melanocortin system is crucial for the control of appetite and body weight. Two of the five melanocortin receptors, MC3R and MC4R are involved in hypothalamic control of energy homeostasis, with the MC4R having the major influence. It is
Hisadome, Kazunari +11 more
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The hypothalamus as the central regulator of energy balance and its impact on current and future obesity treatments [PDF]
Archives of Endocrinology and MetabolismThe hypothalamus is a master regulator of energy balance in the body. First-order hypothalamic neurons localized in the arcuate nucleus sense systemic signals that indicate the energy stores in the body.
Bruna Bombassaro +2 more
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Hypothalamic paraventricular nucleus activation contributes to neurohumoral excitation in rats with heart failure [PDF]
Regenerative Medicine Research, 2014 Heart failure (HF) is a serious cardiovascular disease and is characterized by exaggerated sympathetic activity. In this paper, we review these limited studies, with particular emphasis on examining the role of the paraventricular nucleus (PVN) in the ...
Kang Yu-Ming +7 more
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Advanced Science, EarlyView.RCI is associated with functional suppression of oxytocinergic neurons in the PVN. Reduced PVNOXT neuronal activity contributes to altered sympathetic regulation involving the IML–sympathetic chain pathway, accompanied by changes in norepinephrine signaling at the BTI.
Liyang Wan +8 more
wiley +1 more source
Circadian rhythm mechanism in the suprachiasmatic nucleus and its relation to the olfactory system
Frontiers in Neural CircuitsAnimals need sleep, and the suprachiasmatic nucleus, the center of the circadian rhythm, plays an important role in determining the timing of sleep. The main input to the suprachiasmatic nucleus is the retinohypothalamic tract, with additional inputs ...
Yusuke Tsuno, Michihiro Mieda
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