Results 61 to 70 of about 12,608 (191)
iMetaOmics, Volume 3, Issue 1, March 2026.Estuaries are vital hotspots for antibiotic resistance genes (ARGs) due to substantial antibiotic pollution. Although viruses have been proposed as key reservoirs and important disseminators of ARGs in environments, their contribution to the estuarine antibiotic resistome remains largely unknown.
Xiao‑Qing Luo +9 more
wiley +1 more source
Recruitment of the ParG Segregation Protein to Different Affinity DNA Sites [PDF]
Journal of Bacteriology, 2009 ABSTRACTThe segrosome is the nucleoprotein complex that mediates accurate plasmid segregation. In addition to its multifunctional role in segrosome assembly, the ParG protein of multiresistance plasmid TP228 is a transcriptional repressor of theparFGpartition genes.
Zampini, Massimiliano +4 more
openaire +3 more sources
Journal for ImmunoTherapy of CancerBackground Ovarian cancer is the most lethal gynecological malignancy, with limited treatment options after failure of standard therapies. Despite the potential of poly(ADP-ribose) polymerase inhibitors in treating DNA damage response (DDR)-deficient ...
Lorna Rodriguez-Rodriguez +14 more
doaj +1 more source
Animals, 2021 Identifying the licking behaviour in beef cattle may provide a means to measure time spent licking for estimating individual block supplement intake. This study aimed to determine the effectiveness of tri-axial accelerometers deployed in a neck-collar ...
Gamaliel Simanungkalit +4 more
doaj +1 more source
Partial and global representations of finite groups
, 2020 Given a subgroup H of a finite group G, we begin a systematic study of the partial representations of G that restrict to global representations of H.
D'Adderio, Michele +3 more
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Journal of Inherited Metabolic Disease, Volume 49, Issue 2, March 2026.ABSTRACT Arginase 1 deficiency (ARG1‐D) is an ultra‐rare inherited metabolic disorder of the urea cycle, caused by partial or complete loss of arginase 1 function, characterised by hyperargininaemia and a distinct, progressive neurological phenotype. The clinical development programme of pegzilarginase, a recombinant human ARG1 enzyme therapy, provides
Mattias Rudebeck +10 more
wiley +1 more source
Poly (ADP-ribose) glycohydrolase (PARG) and its therapeutic potential
Frontiers in Bioscience, 2009 Poly (ADP-robose) glycohydrolase (PARG) is a catabolic enzyme that cleaves ADP-ribose polymers synthesized by members of the poly (ADP-ribose) polymerase (PARP) family of enzymes. The growing evidence supports the importance of a tight control of poly (ADP-ribose) metabolism by the two major enzymes, PARP-1 and PARG.
Wookee, Min, Zhao-Qi, Wang
openaire +2 more sources
Journal of Cellular and Molecular Medicine, Volume 30, Issue 6, March 2026.ABSTRACT Our previous studies have demonstrated that seven in absentia homologue 1 (SIAH1), an E3 ubiquitin ligase, is downregulated in hepatocellular carcinoma (HCC) and regulates substrate ubiquitination. However, the molecular mechanisms governing reduced SIAH1 expression in HCC remain unclear.
Jie Qiu +6 more
wiley +1 more source
Molecular Insights into Poly(ADP-ribose) Recognition and Processing
Biomolecules, 2012 Poly(ADP-ribosyl)ation is a post-translational protein modification involved in the regulation of important cellular functions including DNA repair, transcription, mitosis and apoptosis.
Ivan Ahel +3 more
doaj +1 more source
A topological characterization of the Moufang property for compact polygons
, 2016 We prove a purely topological characterization of the Moufang property for disconnected compact polygons in terms of convergence groups. As a consequence, we recover the fact that a locally finite thick affine building of rank 3 is a Bruhat-Tits building
Radu, Nicolas
core +1 more source