Results 81 to 90 of about 6,989 (168)

PARG Governs a PARylation-Ubiquitination Toggle that Stabilizes RAD51AP1 to Drive Homologous Recombination-Mediated Chemoresistance. [PDF]

Cancer Res
He H, Hu Y, Lu Y, Deng M, Bao Q, Zu D, Zhong Y, Zhang C, You C, Du X, Liu S, He Y, Liu M, Gao L, Gao X, Liu H, Huang Y, Chen Y, Rong D, Tainer JA, Jing J, Shi Y, Shen HM, Ye Z, Cheng X.   +24 more
europepmc   +1 more source

Homogeneous Time-Resolved Fluorescence-Based Assay to Screen ADP-Ribosyl Hydrolase Inhibitors. [PDF]

Bio Protoc
Yu A, Wu D.
europepmc   +1 more source

Delaying Stress Granule Disassembly by PARG Inhibition Attenuates Renal Tubular Cell Pyroptosis in Acute Kidney Injury. [PDF]

Int J Mol Sci
Song Y, Jiang S, Yang M, Zhu J, Hu B, Su H.   +5 more
europepmc   +1 more source

The inhibition of PARG attenuates DNA repair in hepatocellular carcinoma

Molecular Biomedicine, 2023
Longpo Geng, Yaling Sun, Mingming Zhu, Hongda An, Yunzheng Li, Yuanxiang Lao, Yongli Zhang, Binghua Li, Jie Ni, Zhu Xu   +9 more
openaire   +3 more sources

Overcoming Resistance to PARP Inhibitors in BRCA-Mutated Cancers: Mechanisms and Therapeutic Strategies. [PDF]

J Cancer
Guo J, Wang Y, Li J, Jiang Z.
europepmc   +1 more source

CHD1L maintains genome integrity by facilitating okazaki fragment maturation. [PDF]

Nucleic Acids Res
Nie L, Fu J, Huang M, Zhang H, Ma T, Yang C, Li S, Wang C, Chen J.   +8 more
europepmc   +1 more source

The Expanding Landscape of ADP-Ribosylation: Protein, DNA, RNA, and Mitochondrial Regulation. [PDF]

Chem Res Toxicol
Sin YC, Zhao L.
europepmc   +1 more source

Silencing PARG decreases invasion in CT26 cells.

International journal of clinical and experimental pathology
In this study we investigated the effect of poly (ADP-ribose) glycohydrolase (PARG) deficiency on the ability of invasion in CT26 murine colon carcinoma cell and its possible mechanism. We examined the effects of PARG protein knockdown by RNA interference on invasion, migration, and matrix adhesion of colon carcinoma CT26 cell line in vitro and using a
Ting, Lin, Yi, Tang, Ming, Xiao, Ming, Li, Qingshu, Li, Lian, Yang, Xian, Li, Yi, Yang, Yalan, Wang   +8 more
openaire   +1 more source

Active maintenance of meiosis-specific chromosome structures in <i>Caenorhabditis elegans</i> by the deubiquitinase DUO-1. [PDF]

Proc Natl Acad Sci U S A
Strand LG, Choi CP, McCoy S, Nsamba ET, Silva N, Villeneuve AM.   +5 more
europepmc   +1 more source

Identification of Paraptosis-Related Renal Cell Carcinoma Subtypes, Construction of a Prognostic Signature, and Determination of Tumor Microenvironment Landscape Using Bioinformatic Analysis and Experimental Verification. [PDF]

Curr Issues Mol Biol
Qin M, Chen M, Gan Y, Feng X, Huang P, Meng F, Yang Y.   +6 more
europepmc   +1 more source