Results 81 to 90 of about 6,727 (169)

Poly(ADP-ribose) glycohydrolase enforces p21 degradation via dePARylation to promote gastric cancer progression. [PDF]

J Clin Invest
Hu Y, Bao Q, Huang Y, Wang Y, Zhao X, Nan J, Meng Y, Deng M, Li Y, Zhuang Z, He H, Zu D, Zhong Y, Zhang C, Wang B, Li R, He Y, Wang Q, Liu M, Tainer JA, Shi Y, Cheng X, Jing J, Ye Z.   +23 more
europepmc   +1 more source

The inhibition of PARG attenuates DNA repair in hepatocellular carcinoma

Molecular Biomedicine, 2023
Longpo Geng, Yaling Sun, Mingming Zhu, Hongda An, Yunzheng Li, Yuanxiang Lao, Yongli Zhang, Binghua Li, Jie Ni, Zhu Xu   +9 more
openaire   +3 more sources

The Expanding Landscape of ADP-Ribosylation: Protein, DNA, RNA, and Mitochondrial Regulation. [PDF]

Chem Res Toxicol
Sin YC, Zhao L.
europepmc   +1 more source

The antibacterial effect of Tanacetum argyrophyllum essential oil on kanamycin-resistant Escherichia coli by disruption of energy metabolism and proton fluxes. [PDF]

Sci Rep
Margaryan L, Tadevosyan S, Sahakyan A, Trchounian K, Sahakyan N.   +4 more
europepmc   +1 more source

Active maintenance of meiosis-specific chromosome structures in <i>Caenorhabditis elegans</i> by the deubiquitinase DUO-1. [PDF]

Proc Natl Acad Sci U S A
Strand LG, Choi CP, McCoy S, Nsamba ET, Silva N, Villeneuve AM.   +5 more
europepmc   +1 more source

Identification of Paraptosis-Related Renal Cell Carcinoma Subtypes, Construction of a Prognostic Signature, and Determination of Tumor Microenvironment Landscape Using Bioinformatic Analysis and Experimental Verification. [PDF]

Curr Issues Mol Biol
Qin M, Chen M, Gan Y, Feng X, Huang P, Meng F, Yang Y.   +6 more
europepmc   +1 more source

Silencing PARG decreases invasion in CT26 cells.

International journal of clinical and experimental pathology
In this study we investigated the effect of poly (ADP-ribose) glycohydrolase (PARG) deficiency on the ability of invasion in CT26 murine colon carcinoma cell and its possible mechanism. We examined the effects of PARG protein knockdown by RNA interference on invasion, migration, and matrix adhesion of colon carcinoma CT26 cell line in vitro and using a
Ting, Lin, Yi, Tang, Ming, Xiao, Ming, Li, Qingshu, Li, Lian, Yang, Xian, Li, Yi, Yang, Yalan, Wang   +8 more
openaire   +1 more source

Synergistic Cellular Toxicity from Inhibition of Poly(ADP-ribose) Glycohydrolase (PARG) and Ubiquitin-Specific Protease 1 (USP1). [PDF]

Toxics
Leonard SM, Pearson CR, Roos WP, Sobol RW.   +3 more
europepmc   +1 more source

Versatile and sensitive detection of mono- and poly(ADP-ribosyl)ation reveals XRCC1-dependent remodelling of PARP1 signalling. [PDF]

Nat Commun
Dauben H, Mihaljević M, Kolvenbach A, Palumbieri MD, Kapsali C, Huppertz I, Matić I.   +6 more
europepmc   +1 more source

PARP-2 catalytic activity drives replication-ICL repair in an allele-specific manner during germline development. [PDF]

PLoS Genet
Ren X, Hu A, Liu Z, Kim S, Kim HM.
europepmc   +1 more source