Mitochondria and the Actin Cytoskeleton in Neurodegeneration
Cytoskeleton, EarlyView.ABSTRACT Mitochondrial dysfunction and cytoskeletal disorganization are widely recognized hallmarks of neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), and amyotrophic lateral sclerosis (ALS).
Shivani Tuli +3 more
wiley +1 more source
An approach to software maintenance support using a syntactic source code analyser data base : this thesis is presented in a partial fulfillment of the requirements for the degree of Master of Arts in Computer Science at Massey University [PDF]
, 1987 In this thesis, the development of a software maintenance tool called a syntactic source code analyser (SSCA) is summarised. An SSCA supports other maintenance tools which interact with source code by creating a data base of source information which has ...
Parkin, Peter Vivian
core
An investigation into the effect of thickness of titanium dioxide and gold-silver nanoparticle titanium dioxide composite thin-films on photocatalytic activity and photo-induced oxygen production in a sacrificial system [PDF]
, 2011 Thin films of titanium dioxide and titanium dioxide with incorporated gold and silver nanoparticles were deposited onto glass microscope slides, steel and titanium foil coupons by two sol–gel dip-coating methods.
Darr, J. A. +5 more
core +1 more source
PINK1-Mediated Phosphorylation of Parkin Boosts Parkin Activity in Drosophila
PLoS Genetics, 2014 Two genes linked to early onset Parkinson's disease, PINK1 and Parkin, encode a protein kinase and a ubiquitin-ligase, respectively. Both enzymes have been suggested to support mitochondrial quality control. We have reported that Parkin is phosphorylated at Ser65 within the ubiquitin-like domain by PINK1 in mammalian cultured cells. However, it remains
Kahori Shiba-Fukushima +3 more
openaire +4 more sources
Dapagliflozin alleviates high‐fat‐induced obesity cardiomyopathy by inhibiting ferroptosis
ESC Heart Failure, Volume 12, Issue 2, Page 1358-1373, April 2025.Abstract Aim: Dapagliflozin (Dapa) is a novel hypoglycaemic agent with multiple cardiovascular protective effects, and it is widely used in treatment of heart failure patients, but whether it can improve obese phenotype of heart failure and its mechanism is still unclear.
Di Chen +7 more
wiley +1 more source
XANES in (TMTSeF)2Re04: Polarization Dependence of the Se K-Edge [PDF]
, 1983 We have measured XANES (X-ray Absorption Near Edge Spectra) near the Re Li (i=l,II,III) edges in (TMTTF)2Re04 and (TMTSeF) 2Re04 and the Se K edge in the latter compound.
Acrivos, Juana Vivó, Parkin, S.S. P.
core +2 more sources
X-ray emission from interacting massive binaries: a review of 15 years of progress [PDF]
, 2015 Previous generations of X-ray observatories revealed a group of massive binaries that were relatively bright X-ray emitters. This was attributed to emission of shock-heated plasma in the wind-wind interaction zone located between the stars.
Naze, Yael, Rauw, Gregor
core +1 more source
Environmental and Molecular Mutagenesis, EarlyView.Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons +17 more
wiley +1 more source
Ubiquitin, proteasome and parkin
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2004 The ubiquitin-proteasome system (UPS) is important for intracellular proteolysis, and is responsible for a diverse array of biologically important cellular processes, such as cell-cycle progression, signaling cascades and developmental programs. This system is also involved in the protein quality control, which maintains the health of the cell.
Tanaka, Keiji +3 more
openaire +2 more sources
Food Bioengineering, EarlyView.Synergistic isoflavone‐probiotic action modulated metabolic, microbial and ovarian pathway ABSTRACT Polycystic ovary syndrome (PCOS) is a prevalent metabolic–endocrine disorder characterized by insulin resistance, hyperandrogenism, chronic inflammation, oxidative stress, and ovarian dysfunction, with growing evidence implicating gut microbiota ...
Jeyavelkumaran Renukadevi +4 more
wiley +1 more source