Results 71 to 80 of about 59,114 (301)
Scientific Reports, 2020 Abnormal iron accumulation caused by elevated levels of divalent metal transporter 1 (DMT1) contributes to progressive neurodegeneration in Parkinson's disease (PD). Parkin is a E3 ubiquitin ligase for the ubiquitination of DMT1.
Yanmin Zhong +6 more
doaj +1 more source
Recent Advances in Carbon Cathode Materials toward High‐Performing Zinc‐Ion Hybrid Supercapacitors
Advanced Science, EarlyView.Aqueous zinc‐ion hybrid supercapacitors (ZHSCs) have emerged as promising next‐generation electrochemical energy‐storage devices. Porous carbon materials have been extensively studied as cathodes, with advances in tailoring pore structures and material properties to enhance performance.
Take Hirooka +3 more
wiley +1 more source
Ubiquitin, proteasome and parkin
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2004 The ubiquitin-proteasome system (UPS) is important for intracellular proteolysis, and is responsible for a diverse array of biologically important cellular processes, such as cell-cycle progression, signaling cascades and developmental programs. This system is also involved in the protein quality control, which maintains the health of the cell.
Tanaka, Keiji +3 more
openaire +2 more sources
Topological Materials and Related Applications
Advanced Electronic Materials, EarlyView.This review covers topological materials—including topological insulators, quantum valley Hall and quantum spin Hall insulators, and topological Weyl and Dirac semimetals—as well as their most recent advancements in fields such as spintronics, electronics, photonics, thermoelectrics, and catalysis.
Carlo Grazianetti +9 more
wiley +1 more source
BMC Cancer, 2019 Background Progression of breast cancer involves both genetic and epigenetic factors. Parkin gene has been identified as a tumor suppressor gene in the pathogenesis of various cancers.
Khushnuma Wahabi +5 more
doaj +1 more source
Humanin Mitigates Aβ-Induced Retinal Pigment Epithelium Injury via AMPK-Beclin1-Dependent Mitophagy. [PDF]
Aging CellHumanin (HN) enhanced the clearance of Aβ‐accumulated mitochondria in the RPE while preserving retinal function and RPE barrier integrity. HN activated AMP‐activated protein kinase (AMPK), leading to phosphorylation of ULK1 and Beclin1, which promoted the interaction between Beclin1 and Parkin and their translocation to mitochondria.
Jang HY +7 more
europepmc +2 more sources
Advanced Energy Materials, EarlyView.In situ electrochemically induced molecular sieve‐alginate interface layer can suppress chloride‐induced pitting corrosion, hydrogen evolution, and dendrite growth, while regulating zinc ion transport and deposition, thereby protecting the zinc anode in seawater electrolyte.
Yunpeng Zhong +7 more
wiley +1 more source
Neurobiology of Disease, 2009 Parkin is implicated in the pathogenesis of Parkinson's disease. Furthermore, parkin targets misfolded proteins for degradation and protects cells against various forms of cellular stress, including unfolded-protein and oxidative stress.
Maarten E. Witte +6 more
doaj +1 more source
British Educational Research Journal, EarlyView.Abstract Valuing parental engagement, as part of home–school collaboration, can benefit children's learning. This article focuses on parents and school‐based staff's (N = 120) experiences of children's learning occurring at home during the COVID‐19 lockdowns (2020–2021), both school‐mandated and other learning activities.
Ashley Brett +5 more
wiley +1 more source
The costs of extra‐pair behaviours in birds
Biological Reviews, EarlyView.ABSTRACT Extra‐pair behaviours – reproductive behaviours, including those related to copulation and paternity of offspring, amongst animals outside of a social pair bond – have long intrigued behavioural ecologists, particularly from the female animal's perspective.
Jørgen S. Søraker, Jamie Dunning
wiley +1 more source