Results 71 to 80 of about 44,057 (302)

Natural Anionic Interfacial Reconstruction for Suppressing Pitting Corrosion Enables Durable Seawater Zinc‐Ion Batteries

Advanced Energy Materials, EarlyView.
In situ electrochemically induced molecular sieve‐alginate interface layer can suppress chloride‐induced pitting corrosion, hydrogen evolution, and dendrite growth, while regulating zinc ion transport and deposition, thereby protecting the zinc anode in seawater electrolyte.
Yunpeng Zhong, Xuhuan Xiao, Xueru Shi, Haochen Li, Zeshi Li, Zhaohan Wu, Ivan P. Parkin, Guanjie He   +7 more
wiley   +1 more source

Parkin Regulation and Neurodegenerative Disorders [PDF]

Frontiers in Aging Neuroscience, 2016
Parkin is a unique, multifunctional ubiquitin ligase whose various roles in the cell, particularly in neurons, are widely thought to be protective. The pivotal role that Parkin plays in maintaining neuronal survival is underscored by our current recognition that Parkin dysfunction represents not only a predominant cause of familial parkinsonism but ...
Chengwu eZhang, Liting eHang, Tso-Pang eYao, Kah-Leong eLim, Kah-Leong eLim   +4 more
openaire   +3 more sources

The Cost of the National Disability Insurance Scheme: Australia's Print‐Media Discourse

Australian Journal of Social Issues, EarlyView.
ABSTRACT This paper examines the way that Australian newspapers have framed the cost of the National Disability Insurance Scheme (NDIS). Introduced in 2013, the NDIS represented a major change in Australia's disability support policy, moving for the first time to a nationwide universal insurance model.
Meera Chinnappa, Jennifer Smith‐Merry, Kuo‐yi Jade Chang   +2 more
wiley   +1 more source

Alternative Translation Initiation in PRKN Delays the Onset of Parkinson's Disease and Offers a Therapeutic Target

Annals of Neurology, EarlyView.
Objective Biallelic variants in PRKN cause autosomal recessive Parkinson's disease (PD) with a median age at onset of 31 years. When evaluating the 16 previously published carriers of a homozygous deletion of Exon 2 from the International Parkinson's Disease and Movement Disorder Society Gene Database (MDSGene) database, the median age at onset is ...
Arian Hach, Katja Lohmann, Manabu Funayama, Poornima J. Menon, Eva‐Juliane Vollstedt, Teresa Kleinz, Hiroyo Yoshino, Suzanne Lesage, Britta Meier, Carolyn M. Sue, Jean‐Christophe Corvol, Alexis Brice, Nobutaka Hattori, Christine Klein, Aleksandar Rakovic   +14 more
wiley   +1 more source

The Interactive Effect of Interval Training Intensity and Curcumin Supplementation on Mitochondrial Bnip3 and Parkin Gene Expression in the Heart Tissue of Male Rats\' Model of Heart Infarction

Journal of Ardabil University of Medical Sciences, 2022
Background & objectives: The increase of Bnip3 and Parkin plays an important role in maintaining mitochondrial function and inhibiting ROS. A correlation was observed between the mitochondrial respiratory capacity and the subjects' mRNA levels of Bnip3 ...
Mohammad Rasoul Mirzaei, Shahram Gholamrezaei, Ramin Shabani   +2 more
doaj  

Predominance of Ferroptotic Cell Death Mechanisms in Substantia Nigra Neurodegeneration in Parkinson's Disease

Annals of Neurology, EarlyView.
Objective The extent of neuronal loss in Parkinson's disease (PD) and the pathogenic processes underlying neuronal dysfunction and loss remain poorly understood. Here, we analyzed the expression of key molecules representing different cell death signaling pathways and their association with Lewy pathology, dopaminergic (DA) neuron loss and stage of PD ...
Yue Jing Heng, Anusha Jayaraman, Richard Reynolds, Jia Nee Foo   +3 more
wiley   +1 more source

Hepatotoxicity of Nonesterified Fatty Acids to Dairy Cows: Pathophysiological Mechanisms and Prospective Solutions

Animal Research and One Health, EarlyView.
Unregulated inflammation increases non‐esterified fatty acids (NEFAs), and triggers multi‐pathway hepatocyte damage including oxidative stress, mitochondrial dysfunction, and metabolic disorders in dairy cows. ABSTRACT Circulating concentrations of nonesterified fatty acids (NEFAs) are elevated due to lipid mobilization from adipose tissue in ...
Siqing Mao, Yuan Tian, Dan Li, Lei Tian, Hang Yu, Ziling Liu, Xin Gao, Yanqiong Wen, Fachun Wan, Zuo Wang, Weijun Shen, Xinwei Li, Lei Liu   +12 more
wiley   +1 more source

‘A completely different space’: Teachers' perspectives on disadvantage, access to nature and outdoor learning

British Educational Research Journal, EarlyView.
Abstract This study examined teachers' perspectives on how children benefit from time in nature, how disadvantage shapes access and the role of schools in facilitating such access. Drawing on interviews conducted in 2022 with 25 UK primary school teachers who participated in Generation Wild, a nature connection programme for schools in economically ...
Nicola Parkin, Kersty Hobson, Wouter Poortinga, Mark Stead, Julia Newth, Jonathan Reeves, Merideth Gattis   +6 more
wiley   +1 more source

The S-nitrosylation of parkin attenuated the ubiquitination of divalent metal transporter 1 in MPP+-treated SH-SY5Y cells

Scientific Reports, 2020
Abnormal iron accumulation caused by elevated levels of divalent metal transporter 1 (DMT1) contributes to progressive neurodegeneration in Parkinson's disease (PD). Parkin is a E3 ubiquitin ligase for the ubiquitination of DMT1.
Yanmin Zhong, Xin Li, Xixun Du, Mingxia Bi, Fengtong Ma, Junxia Xie, Hong Jiang   +6 more
doaj   +1 more source

Parental involvement and engagement during COVID‐19 lockdowns: School staff and parents' reflections about children's learning at home

British Educational Research Journal, EarlyView.
Abstract Valuing parental engagement, as part of home–school collaboration, can benefit children's learning. This article focuses on parents and school‐based staff's (N = 120) experiences of children's learning occurring at home during the COVID‐19 lockdowns (2020–2021), both school‐mandated and other learning activities.
Ashley Brett, Bonny L. Hartley, Deborah Wallace, Adewale Magaji, Lorraine Smith, Rachel Wolfendale   +5 more
wiley   +1 more source