Levodopa/carbidopa microtablets in Parkinson’s disease: a study of pharmacokinetics and blinded motor assessment [PDF]
, 2017 Marina Senek +12 more
openalex +1 more source
Circular RNA PTPN4 Contributes to Blood‐Brain Barrier Disruption during Early Epileptogenesis
Advanced Science, EarlyView.Epileptic condition induces CircPTPN4 upregulation, which promotes ECE‐1 expression through competitive sequestration of miR‐145a‐5p. The elevated ECE‐1 catalyzes the ET‐1 production, leading to p38/MAPK pathway activation and subsequent downregulation of tight junction protein expression. This cascade results in increased BBB permeability and enhanced
Jiurong Yang +16 more
wiley +1 more source
Atrophic Myenteric and Submucosal Neurons Are Observed in Parkinson’s Disease [PDF]
, 2019 Bodil Ohlsson, Elisabet Englund
openalex +1 more source
ANXIETY AND DEPRESSION IN TUNISIAN PATIENTS WITH PARKINSON’S DISEASE [PDF]
, 2023 S. Kolsi +8 more
openalex +1 more source
PH1 RISK OF PNEUMONIA DUE TO INCIDENT ANTIPSYCHOTIC DRUG USE AMONG PARKINSON’S DISEASE PATIENTS [PDF]
Value in Health, 2019 S. Inguva +3 more
openaire +1 more source
Formation of Condition‐Dependent Alpha‐Synuclein Fibril Strain in Artificial Cerebrospinal Fluid
Advanced Science, EarlyView.α‐synuclein aggregation in artificial cerebrospinal fluid (aCSF) leads to a distinct conformation with an electron density pocket motif found in aggregates from PD and MSA patients. Such fibrils has low stability outside the reaction conditions, hinting about the influence of cerebrospinal fluid components not only on the formation, but also on the ...
Rūta Sniečkutė +7 more
wiley +1 more source
Advanced Science, EarlyView.This study establishes a robust and reproducible protocol for generating human otic neuronal spheroids (hONS) from cryopreserved hPSC‐derived pre‐placodal ectoderm cells. These hONS further differentiate into functional SGN‐like neurons, which extend neurite projections toward both murine hair cells and human cortical organoids, thereby forming ...
Gaoying Sun +15 more
wiley +1 more source
Mucuna Pruriens Seeds Extract Loaded Phytosomal Intranasal Gel for the Effective Treatment of Parkinson’s Disease [PDF]
Akshay Kulkarni, Manoj Tare, Meera Singh
openalex +1 more source
The feasibility and acceptability of using a novel wrist worn cueing device to self-manage drooling problems in people with Parkinson’s disease: A pilot study [PDF]
, 2019 Róisín McNaney +6 more
openalex +1 more source