Results 181 to 190 of about 236,137 (343)

Beyond the Classic Segawa Disease, -Associated Neurodegenerative Parkinsonism: Practical Considerations for Physicians [PDF]

Journal of Movement Disorders, 2017
Jirat Chenbhanich, Jirada Sringean, Roongroj Bhidayasiri   +2 more
doaj   +1 more source

Additional file 1: of Regional microglia are transcriptionally distinct but similarly exacerbate neurodegeneration in a culture model of Parkinsonâ s disease

, 2018
Table S1. List of primers used for qRT-PCR. (DOCX 29 kb)
Kostuk, Eric, Jingli Cai, Iacovitti, Lorraine   +2 more
openaire   +1 more source

Computer simulation of some of the motor circuits underlying Parkinson’s disease [PDF]

, 1997
Gabrielle Geller, David V. Reynolds
openalex   +1 more source

Lycium barbarum Glycopeptide Alleviates Neomycin‐Induced Ototoxicity by Inhibiting Tryptophan Hydroxylase‐Mediated Serotonin Biosynthesis

Advanced Science, EarlyView.
Lycium barbarum glycopeptide (LBGP), which is further extracted from Lycium barbarum polysaccharides, exhibits significant protective effects against neomycin‐induced hearing dysfunction including oxidative stress in cochlea and loss of key cells in cochlea.
Yunhao Wu, Li Zhang, Shengda Cao, Jingwen Zhang, Cheng Li, Yunlong Shan, Qiuping Liu, Zhexiong Yu, Qiaojun Fang, Yuhua Zhang, Xiaolong Fu, Kwok‐Fai So, Renjie Chai   +12 more
wiley   +1 more source

The effects of coloring therapy on patients with generalized anxiety disorder

Animal Models and Experimental Medicine, Volume 5, Issue 6, Page 502-512, December 2022., 2022
After the intervention, there were statistical differences intra‐and‐inter group comparisons of anxiety, depression, and positive and negative mood scales in the experimental and control groups (p < .05). The minus in anxiety/positive emotions pre‐and‐post intervention in the experimental group was statistically significant compared to the minus in ...
Bosomtwe Samuel, Hongmei Wang, Chengdong Shi, Yongliang Pan, Yuzi Yu, Weiyu Zhu, Zhou Jing   +6 more
wiley   +1 more source

Current Issues in Neurodegenerative Diseases, Vol. 3, Parkinson’s Disease: Symptomatic Versus Preventative Therapy. Edited by E.C. Wolters, ICG Publications, Dordrecht; Current Issues in Neurodegenerative Diseases, Vol. 5, The Functional Role of Dopamine 01 Receptors. Edited by R. J. Vermeulen, ICG Publications, Dordrecht [PDF]

, 1995
R. Grünewald
openalex   +1 more source

Bilirubin Targeting WNK1 to Alleviate NLRP3‐Mediated Neuroinflammation

Advanced Science, EarlyView.
At physiological concentrations, bilirubin binds to the kinase domain of WNK1, thereby augmenting its activity and facilitating the phosphorylation of downstream SPAK/OSR1. This phosphorylation inhibits KCC2 activity, leading to elevate intracellular chloride levels in neurons.
Linfei Mao, Jiayu Lu, Quanjun Yang, Zhenqi Liu, Cuiping Wu, Bingbing Ke, Kaiyan Su, Haolin Yuan, Yaqi Cui, Yao Wang, Richard Salvi, Guang Yang, Shankai Yin, Feng Liu, Chunyan Li   +14 more
wiley   +1 more source

Fatigue in Patients with Parkinson’s Disease [PDF]

, 2000
Kazuo Abe, Mayako Takanashi, Takehiko Yanagihara   +2 more
openalex   +1 more source

Single Administration of AAV‐mAtp6v1b2 Gene Therapy Rescues Hearing and Vestibular Disorders Caused by Atp6v1b2‐Induced Lysosomal Dysfunction in Hair Cells

Advanced Science, EarlyView.
Wei et al. establish a hair cell‐specific conditional knockout mouse model (Atp6v1b2fl/fl;Atoh1Cre/+), and demonstrate the importance of Atp6v1b2 for hair cell through maintaining the survival of lysosomes. A single administration of AAV‐ie‐Eh3‐mAtp6v1b2 through scala media at P0‐P2 realizes function compensation and restores hearing and balance ...
Gege Wei, Shiwei Qiu, Xue Gao, Lu Zheng, Yijin Chen, Ying Ma, Haifeng Feng, Jinyuan Yang, Guojie Dong, Huiyi Nie, Weihao Zhao, Xiaoge Li, Guangqin Wang, Wei Xiong, Pu Dai, Yongyi Yuan   +15 more
wiley   +1 more source

α‐Synuclein Pathology Spreads in a Midbrain–Hindbrain Assembloid Model

Advanced Science, EarlyView.
A novel midbrain–hindbrain assembloid model demonstrates the spread of α‐synuclein pathology, a hallmark of Parkinson's disease, mimicking Braak's hypothesis. This model reveals how pathology propagates from the hindbrain to the midbrain, inducing synaptic changes and early signs of neuronal vulnerability. It offers an innovative platform for exploring
Gemma Gomez‐Giro, Daniela Frangenberg, Daniela Vega, Alise Zagare, Kyriaki Barmpa, Paul M. A. Antony, Graham Robertson, Rahman Sabahi‐Kaviani, Kristian Haendler, Nathalie Kruse, Florentia Papastefanaki, Rebecca Matsas, Malte Spielman, Regina Luttge, Jens C. Schwamborn   +14 more
wiley   +1 more source