Results 11 to 20 of about 42,265 (195)

Neuroimaging biomarkers for clinical trials in atypical parkinsonian disorders: Proposal for a Neuroimaging Biomarker Utility System [PDF]

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2019
Introduction Therapeutic strategies targeting protein aggregations are ready for clinical trials in atypical parkinsonian disorders. Therefore, there is an urgent need for neuroimaging biomarkers to help with the early detection of neurodegenerative ...
Thilo vanEimeren, Angelo Antonini, Daniela Berg, Nico Bohnen, Roberto Ceravolo, Alexander Drzezga, Günter U. Höglinger, Makoto Higuchi, Stephane Lehericy, Simon Lewis, Oury Monchi, Peter Nestor, Matej Ondrus, Nicola Pavese, María Cecilia Peralta, Paola Piccini, José Ángel Pineda‐Pardo, Irena Rektorová, María Rodríguez‐Oroz, Axel Rominger, Klaus Seppi, A. Jon Stoessl, Alessandro Tessitore, Stephane Thobois, Valtteri Kaasinen, Gregor Wenning, Hartwig R. Siebner, Antonio P. Strafella, James B. Rowe, MDS Neuroimaging Study Group and the JPND Working Group ASAP‐SynTau   +29 more
doaj   +2 more sources

Nocturnal Manifestations of Atypical Parkinsonian Disorders

Journal of Parkinson’s Disease, 2014
Although nocturnal disturbances are increasingly recognized as an integral part of the continuum of daytime manifestations of Parkinson's disease (PD), there is still little evidence in the medical literature to support the occurrence of these complex ...
Roongroj Bhidayasiri, Onanong Jitkritsadakul, Carlo Colosimo   +2 more
doaj   +3 more sources

Atypical parkinsonian disorders

Chinese Journal of Contemporary Neurology and Neurosurgery, 2011
DOI：10.3969/j.issn.1672-6731.2011.01 ...
Yue HUANG, Shengdi CHEN, Wenning Gregor, et al   +3 more
doaj   +1 more source

Toward Biology-Driven Diagnosis of Atypical Parkinsonian Disorders [PDF]

NeuroSci
Atypical parkinsonian disorders—progressive supranuclear palsy (PSP), corticobasal degeneration (CBD), and multiple system atrophy (MSA)—are rare, rapidly progressive neurodegenerative syndromes characterized by distinct molecular pathologies ...
Oscar Arias-Carrión, Elizabeth Romero-Gutiérrez, Emmanuel Ortega-Robles   +2 more
doaj   +2 more sources

TSPO imaging in parkinsonian disorders. [PDF]

Clin Transl Imaging, 2016
Microglial activation is a key aspect of the neuroinflammatory process in neurodegenerative disorders including idiopathic and atypical parkinsonian disorders. With positron emission tomography (PET) it has become possible to image this phenomenon in vivo and over the last years patterns of microglia activation corresponding with the known distribution
Gerhard A.
europepmc   +5 more sources

Advanced diffusion imaging to track progression in Parkinson’s disease, multiple system atrophy, and progressive supranuclear palsy

NeuroImage: Clinical, 2022
Advanced diffusion imaging which accounts for complex tissue properties, such as crossing fibers and extracellular fluid, may detect longitudinal changes in widespread pathology in atypical Parkinsonian syndromes.
Trina Mitchell, Bradley J. Wilkes, Derek B. Archer, Winston T. Chu, Stephen A. Coombes, Song Lai, Nikolaus R. McFarland, Michael S. Okun, Mieniecia L. Black, Ellen Herschel, Tanya Simuni, Cynthia Comella, Mitra Afshari, Tao Xie, Hong Li, Todd B. Parrish, Ajay S. Kurani, Daniel M. Corcos, David E. Vaillancourt   +18 more
doaj   +1 more source

The Role of Magnetic Resonance Imaging for the Diagnosis of Atypical Parkinsonism

Frontiers in Neurology, 2020
The diagnosis of Parkinson's disease and atypical Parkinsonism remains clinically difficult, especially at the early stage of the disease, since there is a significant overlap of symptoms. Multimodal MRI has significantly improved diagnostic accuracy and
Lydia Chougar, Lydia Chougar, Lydia Chougar, Lydia Chougar, Nadya Pyatigorskaya, Nadya Pyatigorskaya, Nadya Pyatigorskaya, Nadya Pyatigorskaya, Bertrand Degos, Bertrand Degos, David Grabli, Stéphane Lehéricy, Stéphane Lehéricy, Stéphane Lehéricy, Stéphane Lehéricy   +14 more
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Organothiophosphate Induced Acute and Reversible Parkinsonism: Case Report and Literature Review [PDF]

Asia Pacific Journal of Medical Toxicology, 2021
Introduction: Organophosphate compound poisoning is one of the most common causes for admission to the Medical Intensive Care Unit. Parkinsonism is a primary neurotoxic manifestation of organophosphate intoxication.
PRASHANT THAKUR, C SELVAKUMAR, V Kumar
doaj   +1 more source

Dystonia in atypical parkinsonian disorders [PDF]

Parkinsonism & Related Disorders, 2019
Dystonia is common in the classic atypical parkinsonian disorders such as multiple system atrophy, progressive supranuclear palsy and corticobasal degeneration, and to a lesser extent in dementia with Lewy bodies. Its clinical phenomenology, including body distribution, timing of appearance, severity, and relationship to dopaminergic and other ...
Marsili L., Bologna M., Kojovic M., Berardelli A., Espay A. J., Colosimo C.   +5 more
openaire   +3 more sources

Priming mesenchymal stem cells with uric acid enhances neuroprotective properties in parkinsonian models

Journal of Tissue Engineering, 2021
Mesenchymal stem cells (MSCs) are a potential source of cell-based disease-modifying therapy in Parkinsonian disorders. A promising approach to develop in vitro culture methods that mimic natural MSC niche is cell priming.
Ha Na Kim, Jin Young Shin, Dong Yeol Kim, Ji Eun Lee, Phil Hyu Lee   +4 more
doaj   +1 more source