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Neuroimaging biomarkers for clinical trials in atypical parkinsonian disorders: Proposal for a Neuroimaging Biomarker Utility System [PDF]

open access: yesAlzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2019
Introduction Therapeutic strategies targeting protein aggregations are ready for clinical trials in atypical parkinsonian disorders. Therefore, there is an urgent need for neuroimaging biomarkers to help with the early detection of neurodegenerative ...
Thilo vanEimeren   +29 more
doaj   +2 more sources

Atypical parkinsonian disorders

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2011
DOI:10.3969/j.issn.1672-6731.2011.01 ...
Yue HUANG   +3 more
doaj   +1 more source

Toward Biology-Driven Diagnosis of Atypical Parkinsonian Disorders [PDF]

open access: yesNeuroSci
Atypical parkinsonian disorders—progressive supranuclear palsy (PSP), corticobasal degeneration (CBD), and multiple system atrophy (MSA)—are rare, rapidly progressive neurodegenerative syndromes characterized by distinct molecular pathologies ...
Oscar Arias-Carrión   +2 more
doaj   +2 more sources

TSPO imaging in parkinsonian disorders. [PDF]

open access: yesClin Transl Imaging, 2016
Microglial activation is a key aspect of the neuroinflammatory process in neurodegenerative disorders including idiopathic and atypical parkinsonian disorders. With positron emission tomography (PET) it has become possible to image this phenomenon in vivo and over the last years patterns of microglia activation corresponding with the known distribution
Gerhard A.
europepmc   +5 more sources

Neuronal entropy depends on the level of alertness in the parkinsonian Globus Pallidus in vivo [PDF]

open access: yesFrontiers in Neurology, 2014
A new working hypothesis of Parkinson's disease proposes to focus on the central role of entropy increase in the Basal Ganglia in movement disorders. The conditions necessary for entropy increase in vivo are, however, still not fully described.
Daniela Sabrina Andres   +5 more
doaj   +5 more sources

The neurogenetics of atypical parkinsonian disorders. [PDF]

open access: yesSemin Neurol, 2014
Although classic Parkinson disease is the disorder most commonly associated with the clinical feature of parkinsonism, there is in fact a broader spectrum of disease represented by a collection of phenotypically similar neurodegenerative conditions that mimic many of its core features.
Fogel BL, Clark MC, Geschwind DH.
europepmc   +6 more sources

Integrating tele-palliative care for atypical Parkinsonian disorders: Lessons learned from a pilot program. [PDF]

open access: greenClin Park Relat Disord
Afshari M   +7 more
europepmc   +3 more sources

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