Neuroimaging biomarkers for clinical trials in atypical parkinsonian disorders: Proposal for a Neuroimaging Biomarker Utility System [PDF]
Introduction Therapeutic strategies targeting protein aggregations are ready for clinical trials in atypical parkinsonian disorders. Therefore, there is an urgent need for neuroimaging biomarkers to help with the early detection of neurodegenerative ...
Thilo vanEimeren +29 more
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Atypical parkinsonian disorders
DOI:10.3969/j.issn.1672-6731.2011.01 ...
Yue HUANG +3 more
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Toward Biology-Driven Diagnosis of Atypical Parkinsonian Disorders [PDF]
Atypical parkinsonian disorders—progressive supranuclear palsy (PSP), corticobasal degeneration (CBD), and multiple system atrophy (MSA)—are rare, rapidly progressive neurodegenerative syndromes characterized by distinct molecular pathologies ...
Oscar Arias-Carrión +2 more
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TSPO imaging in parkinsonian disorders. [PDF]
Microglial activation is a key aspect of the neuroinflammatory process in neurodegenerative disorders including idiopathic and atypical parkinsonian disorders. With positron emission tomography (PET) it has become possible to image this phenomenon in vivo and over the last years patterns of microglia activation corresponding with the known distribution
Gerhard A.
europepmc +5 more sources
Dopamine transporter SPECT imaging in Parkinson’s disease and parkinsonian disorders [PDF]
Akdemir ÜÖ, Bora Tokçaer A, Atay LÖ.
europepmc +3 more sources
Quantitative susceptibility mapping and blood neurofilament light chain differentiate between parkinsonian disorders. [PDF]
Zhang P +8 more
europepmc +3 more sources
Neuronal entropy depends on the level of alertness in the parkinsonian Globus Pallidus in vivo [PDF]
A new working hypothesis of Parkinson's disease proposes to focus on the central role of entropy increase in the Basal Ganglia in movement disorders. The conditions necessary for entropy increase in vivo are, however, still not fully described.
Daniela Sabrina Andres +5 more
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The neurogenetics of atypical parkinsonian disorders. [PDF]
Although classic Parkinson disease is the disorder most commonly associated with the clinical feature of parkinsonism, there is in fact a broader spectrum of disease represented by a collection of phenotypically similar neurodegenerative conditions that mimic many of its core features.
Fogel BL, Clark MC, Geschwind DH.
europepmc +6 more sources
Integrating tele-palliative care for atypical Parkinsonian disorders: Lessons learned from a pilot program. [PDF]
Afshari M +7 more
europepmc +3 more sources

