Results 1 to 10 of about 55,623 (223)

Parvalbumin Role in Epilepsy and Psychiatric Comorbidities: From Mechanism to Intervention

open access: yesFrontiers in Integrative Neuroscience, 2022
Parvalbumin is a calcium-binding protein present in inhibitory interneurons that play an essential role in regulating many physiological processes, such as intracellular signaling and synaptic transmission.
Lívea Dornela Godoy   +4 more
doaj   +2 more sources

Parvalbumin and parvalbumin chandelier interneurons in autism and other psychiatric disorders

open access: yesFrontiers in Psychiatry, 2022
Parvalbumin (PV) is a calcium binding protein expressed by inhibitory fast-spiking interneurons in the cerebral cortex. By generating a fast stream of action potentials, PV+ interneurons provide a quick and stable inhibitory input to pyramidal neurons ...
Pablo Juárez   +1 more
semanticscholar   +4 more sources

Densities and numbers of calbindin and parvalbumin positive neurons across the rat and mouse brain

open access: yesiScience, 2021
Summary: The calcium-binding proteins parvalbumin and calbindin are expressed in neuronal populations regulating brain networks involved in spatial navigation, memory processes, and social interactions.
Ingvild E. Bjerke   +6 more
doaj   +2 more sources

What Is Parvalbumin for?

open access: yesBiomolecules, 2022
Parvalbumin (PA) is a small, acidic, mostly cytosolic Ca2+-binding protein of the EF-hand superfamily. Structural and physical properties of PA are well studied but recently two highly conserved structural motifs consisting of three amino acids each ...
E. Permyakov, V. Uversky
semanticscholar   +5 more sources

Structural Property, Immunoreactivity and Gastric Digestion Characteristics of Glycated Parvalbumin from Mandarin Fish (Siniperca chuaisi) during Microwave-Assisted Maillard Reaction

open access: yesFoods, 2022
This study was aimed to investigate the structural and immunological properties of parvalbumin from mandarin fish during the Maillard reaction. The microwave-assisted the Maillard reaction was optimized by orthogonal designed experiments.
Jingjing Tai   +8 more
doaj   +1 more source

Fast-spiking parvalbumin-positive interneurons in brain physiology and Alzheimer’s disease

open access: yesMolecular Psychiatry, 2023
Fast-spiking parvalbumin (PV) interneurons are inhibitory interneurons with unique morphological and functional properties that allow them to precisely control local circuitry, brain networks and memory processing.
Sara Hijazi, A. Smit, R. van Kesteren
semanticscholar   +1 more source

Evolution of the Parvalbumin Genes in Teleost Fishes after the Whole-Genome Duplication

open access: yesFishes, 2021
Parvalbumin is considered a major fish allergen. Here, we report the molecular evolution of the parvalbumin genes in bony fishes based on 19 whole genomes and 70 transcriptomes.
Subham Mukherjee   +5 more
doaj   +1 more source

The Role of Parvalbumin Interneurons in Neurotransmitter Balance and Neurological Disease

open access: yesFrontiers in Psychiatry, 2021
While great progress has been made in the understanding of neurological illnesses, the pathologies, and etiologies that give rise to these diseases still remain an enigma, thus, also making treatments for them more challenging.
Lailun Nahar, Blake M Delacroix, H. Nam
semanticscholar   +1 more source

Mature parvalbumin interneuron function in prefrontal cortex requires activity during a postnatal sensitive period

open access: yesbioRxiv, 2022
In their seminal findings, Hubel and Wiesel identified sensitive periods in which experience can exert lasting effects on adult visual cortical functioning and behavior via transient changes in neuronal activity during development.
S. Canetta   +7 more
semanticscholar   +1 more source

Quercetin attenuates the reduction of parvalbumin in middle cerebral artery occlusion animal model

open access: yesLaboratory Animal Research, 2021
Background Calcium is a critical factor involved in modulation of essential cellular functions. Parvalbumin is a calcium buffering protein that regulates intracellular calcium concentrations.
Dong-Ju Park   +3 more
doaj   +1 more source

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