Results 11 to 20 of about 66,774 (189)
Parvalbumin and parvalbumin chandelier interneurons in autism and other psychiatric disorders
Frontiers in Psychiatry, 2022 Parvalbumin (PV) is a calcium binding protein expressed by inhibitory fast-spiking interneurons in the cerebral cortex. By generating a fast stream of action potentials, PV+ interneurons provide a quick and stable inhibitory input to pyramidal neurons and contribute to the generation of gamma oscillations in the cortex.
Pablo Juarez +4 more
openaire +3 more sources
Parvalbumin Interneuron Dendrites Enhance Gamma Oscillations [PDF]
SSRN Electronic Journal, 2021 Dendrites are important determinants of the input-output relationship of single neurons, but their role in network computations is not well understood. Here, we used a combination of dendritic patch-clamp recordings and in silico modeling to determine how dendrites of parvalbumin (PV)-expressing basket cells contribute to network oscillations in the ...
Birgit Kriener, Hua Hu, Koen Vervaeke
openaire +4 more sources
Oncomodulin: The Enigmatic Parvalbumin Protein [PDF]
Frontiers in Molecular Neuroscience, 2019 EF-hand Ca2+-binding protein family members, α- and β-parvalbumins have been studied for decades. Yet, considerable information is lacking distinguishing functional differences between mammalian α-parvalbumin (PVALB) and oncomodulin (OCM), a branded β-parvalbumin.
Leslie K. Climer +7 more
openaire +3 more sources
Subventricular zone stem cells are heterogeneous with respect to their embryonic origins and neurogenic fates in the adult olfactory bulb [PDF]
, 2007 Wedetermined the embryonic origins of adult forebrain subventricular zone (SVZ) stem cells by Cre-lox fate mapping in transgenic mice. We found that all parts of the telencephalic neuroepithelium, including the medial ganglionic eminence and lateral ...
C.H. Papadimitriou +8 more
core +4 more sources
A quantitative study of neurochemically-defined populations of inhibitory interneurons in the superficial dorsal horn of the mouse spinal cord [PDF]
, 2017 Around a quarter of neurons in laminae I-II of the dorsal horn are inhibitory interneurons. These play an important role in modulating somatosensory information, including that perceived as pain or itch.
Boyle, Kieran A. +7 more
core +1 more source
Frontiers in Aging Neuroscience, 2022 The loss of parvalbumin-positive (PV+) neurons in the substantia nigra pars reticulata (SNR) was observed in patients with end-stage Parkinson’s disease (PD) and our previously constructed old-aged Pitx3-A53Tα-Syn × Tau–/– triple transgenic mice model of
Meige Zheng +5 more
doaj +1 more source
Dedicated hippocampal inhibitory networks for locomotion and immobility [PDF]
, 2017 Network activity is strongly tied to animal movement; however, hippocampal circuits selectively engaged during locomotion or immobility remain poorly characterized.
Arriaga, Moises, Han, Edward B
core +2 more sources
Journal of Neurodevelopmental Disorders, 2012 Background Exposure to alcohol in utero is a known cause of mental retardation. Although a certain degree of motor impairment is always associated with fetal alcohol spectrum disorder, little is known about the neurobiological basis of the defective ...
De Giorgio Andrea +3 more
doaj +1 more source
Frontiers in Behavioral Neuroscience, 2021 The early life environment markedly influences brain and behavioral development, with adverse experiences associated with increased risk of anxiety and depressive phenotypes, particularly in females.
Seneca N. Ellis +2 more
doaj +1 more source
Binding of Acrylonitrile to Parvalbumin [PDF]
Toxicological Sciences, 1996 A previous study has shown that acrylonitrile (ACN) has a long half-life in rainbow trout muscle and that [14C]ACN appears to be bound to a 10,000-Da protein in muscle. The labeled protein was purified from muscle of trout exposed to [14C]ACN, separated on 20% SDS-PAGE, and digested for amino acid analysis and sequence analysis. These studies indicated
J J, Lech +4 more
openaire +2 more sources