Results 31 to 40 of about 66,774 (189)

Anxious Profile Influences Behavioral and Immunohistological Findings in the Pilocarpine Model of Epilepsy

Frontiers in Pharmacology, 2021
Anxiety and epilepsy have a complex bidirectional relationship, where a depressive/anxious condition is a factor that can trigger seizures which in turn can aggravate the depressive/anxious condition. In addition, brain structures such as the hippocampus
Silvia Regina Bica Kohek, Maira Licia Foresti, Miriam Marcela Blanco, Clarissa Fantin Cavarsan, Clarissa Fantin Cavarsan, Clivandir Severino da Silva, Luiz E. Mello, Luiz E. Mello   +7 more
doaj   +1 more source

Miro1-dependent mitochondrial dynamics in parvalbumin interneurons [PDF]

eLife, 2020
The spatiotemporal distribution of mitochondria is crucial for precise ATP provision and calcium buffering required to support neuronal signaling. Fast-spiking GABAergic interneurons expressing parvalbumin (PV+) have a high mitochondrial content reflecting their large energy utilization.
Kontou, G, Antonoudiou, P, Podpolny, M, Szulc, BR, Arancibia-Carcamo, IL, Higgs, NF, Lopez-Domenech, G, Salinas, PC, Mann, EO, Kittler, JT   +9 more
openaire   +4 more sources

Postnatal development of thalamic reticular nucleus projections to the anterior thalamic nuclei in rats

European Journal of Histochemistry, 2022
The thalamic reticular nucleus (TRN) projects inhibitory signals to the thalamus, thereby controlling thalamocortical connections. Few studies have examined the development of TRN projections to the anterior thalamic nuclei with regard to axon course ...
Hitoshi Fujita, Kosuke Imura, Masahito Takiguchi, Kengo Funakoshi   +3 more
doaj   +1 more source

Voxel-wise comparisons of cellular microstructure and diffusion-MRI in mouse hippocampus using 3D Bridging of Optically-clear histology with Neuroimaging Data (3D-BOND) [PDF]

, 2018
A key challenge in medical imaging is determining a precise correspondence between image properties and tissue microstructure. This comparison is hindered by disparate scales and resolutions between medical imaging and histology.
Ball, G, Edwards, A D, Jones, M, So, P-W, Stolp, H B, Thornton, C, Tournier, J-D   +6 more
core   +6 more sources

Engineering parvalbumin for the heart: optimizing the Mg2+ binding properties of rat β-parvalbumin [PDF]

Frontiers in Physiology, 2011
Parvalbumin (PV), an EF-hand protein family member, is a delayed calcium buffer that exchanges magnesium for calcium to facilitate fast skeletal muscle relaxation. Genetic approaches that express parvalbumin in the heart also enhance relaxation and show promise of being therapeutic against various cardiac diseases where relaxation is compromised ...
Zhang, Jianchao, Shettigar, Vikram, Zhang, George C., Kindell, Daniel G., Liu, Xiaotong, López, Joseph J., Yerrimuni, Vinatham, Davis, Grace A., Davis, Jonathan P.   +8 more
openaire   +2 more sources

The Role of Parvalbumin-positive Interneurons in Auditory Steady-State Response Deficits in Schizophrenia [PDF]

, 2019
© The Author(s) 2019. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the ...
A.M. Lavoie, AR Woodruff, C Börgers, C-G Hahn, CA Brenner, Chi-Ming A. Chen, CL Beasley, D Vierling-Claassen, D Vierling-Claassen, David A. Lewis, David W. Volk, E Salinas, G Gonzalez-Burgos, GA Light, GP Krishnan, Hanna Thuné, Henry Markram, I Wonodi, J. Szabadics, Joshua T. Kantrowitz, JS Kwon, KM Spencer, KM Spencer, KM Spencer, L KRISTIANSEN, LS Overstreet, M Bartos, M Carlén, Monica Beneyto, Monika P. Jadi, MW Howard, N Hajos, Nadezhda V. Povysheva, P Fries, P Steullet, P Teale, Pascal Fries, R Tsuchimoto, Robin Tremblay, RY Cho, S Keros, T Hashimoto, T Mäki-Marttunen, T-U Woo, Tuomo Mäki-Marttunen, Y Kawaguchi   +45 more
core   +2 more sources

Parvalbumin in rat kidney [PDF]

FEBS Letters, 1986
The Ca2+‐binding parvalbumin has been purified for the first time from rat kidney. Its biochemical and immunological properties were indistinguishable from the muscle counterpart. By immunohistochemical methods parvalbumin was localized in part of the distal tubule and proximal collecting duct, similar to the vitamin D‐dependent Ca2+‐binding protein ...
Schneeberger, Peter R., Heizmann, Claus W.   +1 more
openaire   +2 more sources

What Is Parvalbumin for?

Biomolecules, 2022
Parvalbumin (PA) is a small, acidic, mostly cytosolic Ca2+-binding protein of the EF-hand superfamily. Structural and physical properties of PA are well studied but recently two highly conserved structural motifs consisting of three amino acids each (clusters I and II), which contribute to the hydrophobic core of the EF-hand domains, have been revealed.
Eugene A. Permyakov, Vladimir N. Uversky
openaire   +4 more sources

Altered Disrupted-in-Schizophrenia-1 Function Affects the Development of Cortical Parvalbumin Interneurons by an Indirect Mechanism.

PLoS ONE, 2016
Disrupted-in-Schizophrenia-1 (DISC1) gene has been linked to schizophrenia and related major mental illness. Mouse Disc1 has been implicated in brain development, mainly in the proliferation, differentiation, lamination, neurite outgrowth and synapse ...
Malgorzata Borkowska, J Kirsty Millar, David J Price   +2 more
doaj   +1 more source

Visual attention deficits in schizophrenia can arise from inhibitory dysfunction in thalamus or cortex [PDF]

, 2018
Schizophrenia is associated with diverse cognitive deficits, including disorders of attention-related oculomotor behavior. At the structural level, schizophrenia is associated with abnormal inhibitory control in the circuit linking cortex and thalamus ...
Barbas, Helen, Bullock, Daniel, John, Yohan J., Zikopoulos, Basilis   +3 more
core   +1 more source