Results 31 to 40 of about 55,623 (223)
Calretinin as a marker for premotor neurons involved in upgaze in human brainstem
Frontiers in Neuroanatomy, 2015 Eye movements are generated by different premotor pathways. Damage to them can cause specific deficits of eye movements, such as saccades. For correlative clinico-anatomical post-mortem studies of cases with eye movement disorders it is essential to ...
Christopher eAdamczyk +6 more
doaj +1 more source
Frontiers in Pharmacology, 2021 Anxiety and epilepsy have a complex bidirectional relationship, where a depressive/anxious condition is a factor that can trigger seizures which in turn can aggravate the depressive/anxious condition. In addition, brain structures such as the hippocampus
Silvia Regina Bica Kohek +7 more
doaj +1 more source
Nature Communications, 2019 The formation and maintenance of spatial representations within hippocampal cell assemblies is strongly dictated by patterns of inhibition from diverse interneuron populations.
Matt Udakis +4 more
semanticscholar +1 more source
Miro1-dependent mitochondrial dynamics in parvalbumin interneurons [PDF]
eLife, 2020 The spatiotemporal distribution of mitochondria is crucial for precise ATP provision and calcium buffering required to support neuronal signaling. Fast-spiking GABAergic interneurons expressing parvalbumin (PV+) have a high mitochondrial content reflecting their large energy utilization.
Kontou, G +9 more
openaire +4 more sources
European Journal of Histochemistry, 2022 The thalamic reticular nucleus (TRN) projects inhibitory signals to the thalamus, thereby controlling thalamocortical connections. Few studies have examined the development of TRN projections to the anterior thalamic nuclei with regard to axon course ...
Hitoshi Fujita +3 more
doaj +1 more source
Engineering parvalbumin for the heart: optimizing the Mg2+ binding properties of rat β-parvalbumin [PDF]
Frontiers in Physiology, 2011 Parvalbumin (PV), an EF-hand protein family member, is a delayed calcium buffer that exchanges magnesium for calcium to facilitate fast skeletal muscle relaxation. Genetic approaches that express parvalbumin in the heart also enhance relaxation and show promise of being therapeutic against various cardiac diseases where relaxation is compromised ...
Zhang, Jianchao +8 more
openaire +2 more sources
Parvalbumin in rat kidney [PDF]
FEBS Letters, 1986 The Ca2+‐binding parvalbumin has been purified for the first time from rat kidney. Its biochemical and immunological properties were indistinguishable from the muscle counterpart. By immunohistochemical methods parvalbumin was localized in part of the distal tubule and proximal collecting duct, similar to the vitamin D‐dependent Ca2+‐binding protein ...
Schneeberger, Peter R. +1 more
openaire +2 more sources
PLoS ONE, 2016 Disrupted-in-Schizophrenia-1 (DISC1) gene has been linked to schizophrenia and related major mental illness. Mouse Disc1 has been implicated in brain development, mainly in the proliferation, differentiation, lamination, neurite outgrowth and synapse ...
Malgorzata Borkowska +2 more
doaj +1 more source
The Parvalbumin Hypothesis of Autism Spectrum Disorder
Frontiers in Cellular Neuroscience, 2020 The prevalence of autism spectrum disorder (ASD)—a type of neurodevelopmental disorder—is increasing and is around 2% in North America, Asia, and Europe.
F. Filice +4 more
semanticscholar +1 more source
Developmental Expression of Calcium-Binding Protein-Containing Neurons in Neocortical Transplants
Cell Transplantation, 1998 The present study examined the development of calcium binding protein-containing neurons in a timed series of fetal neocortical transplants. The immunoexpression of parvalbumin and calbindin, which are subpopulations of GABAergic neurons, have been ...
Jeffrey M. Rosenstein +3 more
doaj +1 more source