Results 81 to 90 of about 66,774 (189)

The likely effects of thermal climate change on vertebrate skeletal muscle mechanics with possible consequences for animal movement and behaviour [PDF]

open access: yes, 2019
Climate change can involve alteration in the local temperature that an animal is exposed to, which in turn may affect skeletal muscle temperature.
Abrahams   +100 more
core   +1 more source

The malleable brain: plasticity of neural circuits and behavior: A review from students to students [PDF]

open access: yes, 2017
One of the most intriguing features of the brain is its ability to be malleable, allowing it to adapt continually to changes in the environment. Specific neuronal activity patterns drive long-lasting increases or decreases in the strength of synaptic ...
Adeniyi, Philip A.   +32 more
core   +2 more sources

Rapid, learning-induced inhibitory synaptogenesis in murine barrel field [PDF]

open access: yes, 2010
The structure of neurons changes during development and in response to injury or alteration in sensory experience. Changes occur in the number, shape, and dimensions of dendritic spines together with their synapses. However, precise data on these changes
Cybulska-Klosowicz, A   +6 more
core   +1 more source

Optimisation of an extraction technique of fish allergens suitable for detection and diagnosis

open access: yesCzech Journal of Food Sciences, 2017
An optimised protocol for the extraction of allergenic proteins in fish was developed. Twelve existing or modified extraction buffers were evaluated based on the amount and quality of obtained 12 kDa IgG-binding protein (major fish allergen parvalbumin ...
Jiaju Ma   +3 more
doaj   +1 more source

Dendritic spike induction of postsynaptic cerebellar LTP [PDF]

open access: yes, 2008
The architecture of parallel fiber (PF) axons contacting cerebellar Purkinje neurons (PNs) retains spatial information over long distances. PF synapses can trigger local dendritic calcium spikes, but whether and how this calcium signal leads to plastic ...
Kaspar E. Vogt, Marco Canepari
core   +1 more source

Disrupted GABAergic facilitation of working memory performance in people with schizophrenia. [PDF]

open access: yes, 2020
ObjectivesGamma-Amiobutyric acid (GABA) is a primary inhibitory neurotransmitter that facilitates neural oscillations that coordinate neural activity between brain networks to facilitate cognition.
Carter, CS   +7 more
core  

TNFα induces Ca2+ influx to accelerate extrinsic apoptosis in hepatocellular carcinoma cells [PDF]

open access: yes, 2018
BACKGROUND: Tumor necrosis factor-α has been proven an effective anticancer agent in preclinical studies. However, the translation of TNFα from research to clinic has been blocked by significant systemic toxicity and limited efficacy at maximal tolerated
Ji, Xiaoying   +10 more
core   +4 more sources

Distribution Patterns of Three Molecularly Defined Classes of GABAergic Neurons Across Columnar Compartments in Mouse Barrel Cortex

open access: yesFrontiers in Neuroanatomy, 2019
The mouse somatosensory cortex is an excellent model to study the structural basis of cortical information processing, since it possesses anatomically recognizable domains that receive different thalamic inputs, which indicates spatial segregation of ...
Zsuzsanna Almási   +3 more
doaj   +1 more source

Organic Cation Transporter 3 (OCT3) Is Localized to Intracellular and Surface Membranes in Select Glial and Neuronal Cells Within the Basolateral Amygdaloid Complex of Both Rats and Mice [PDF]

open access: yes, 2016
Organic cation transporter 3 (OCT3) is a high-capacity, low-affinity transporter that mediates corticosterone-sensitive uptake of monoamines including norepinephrine, epinephrine, dopamine, histamine and serotonin. OCT3 is expressed widely throughout the
Chan, June   +3 more
core   +2 more sources

Application of Fluorescence Two-Dimensional Difference In-Gel Electrophoresis as a Proteomic Biomarker Discovery Tool in Muscular Dystrophy Research

open access: yesBiology, 2013
In this article, we illustrate the application of difference in-gel electrophoresis for the proteomic analysis of dystrophic skeletal muscle. The mdx diaphragm was used as a tissue model of dystrophinopathy.
Steven Carberry   +3 more
doaj   +1 more source

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