Endogenous molecules induced by a pathogen-associated molecular pattern (PAMP) elicit innate immunity in shrimp. [PDF]
PLoS ONE, 2014 Invertebrates rely on an innate immune system to combat invading pathogens. The system is initiated in the presence of cell wall components from microbes like lipopolysaccharide (LPS), β-1,3-glucan (βG) and peptidoglycan (PG), altogether known as ...
Yu-Yuan Chen +11 more
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Regulated expression of pathogen-associated molecular pattern molecules in Staphylococcus epidermidis: quorum-sensing determines pro-inflammatory capacity and production of phenol-soluble modulins [PDF]
Cellular microbiology, 2004 Phenol-soluble modulin (PSM) is a peptide complex produced by the nosocomial pathogen Staphylococcus epidermidis that has a strong capacity to activate the human innate immune response. We developed a novel method based on liquid chromatography-mass spectrometry (LC-MS) to quantify the production of the individual PSM components.
Cuong Vuong +5 more
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Hyperconservation of the N -Formyl Peptide Binding Site of M3 : Evidence that M3 Is an Old Eutherian Molecule with Conserved Recognition of a Pathogen-Associated Molecular Pattern [PDF]
The Journal of Immunology, 2003 AbstractThe mouse MHC class I-b molecule H2-M3 has unique specificity for N-formyl peptides, derived from bacteria (and mitochondria), and is thus a pathogen-associated molecular pattern recognition receptor (PRR). To test whether M3 was selected for this PRR function, we studied M3 sequences from diverse murid species of murine genera Mus, Rattus ...
C. Kuyler Doyle +4 more
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Effect of oestradiol and pathogen‐associated molecular patterns on class II‐mediated antigen presentation and immunomodulatory molecule expression in the mouse female reproductive tract [PDF]
Immunology, 2011 Summary Cells of the female reproductive tract (FRT) can present antigen to naive and memory T cells. However, the effects of oestrogen, known to modulate immune responses, on antigen presentation in the FRT remain undefined.
Daniel Ochiel +3 more
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Herbal microbiomes are plant-specific and rich in immune-stimulating pathogen-associated molecular pattern molecules [PDF]
The Journal of Pharmacology and Experimental Therapeutics, 2023 Elizabeth Mazzio +4 more
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NLRP3: Role in ischemia/reperfusion injuries
Frontiers in Immunology, 2022 NLR family pyrin domain containing 3 (NLRP3) is expressed in immune cells, especially in dendritic cells and macrophages and acts as a constituent of the inflammasome.
Soudeh Ghafouri-Fard +10 more
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Chromatin-Associated Molecular Patterns (CAMPs) in sepsis
Cell Death and Disease, 2022 Several molecular patterns have been identified that recognize pattern recognition receptors. Pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs) are commonly used terminologies to classify molecules ...
Colleen P. Nofi, Ping Wang, Monowar Aziz
doaj +1 more source
Frontiers in Immunology, 2023 Pattern recognition receptors are primitive sensors that arouse a preconfigured immune response to broad stimuli, including nonself pathogen-associated and autologous damage-associated molecular pattern molecules.
Tian Wang +6 more
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Post-Translational Modification of HMGB1 Disulfide Bonds in Stimulating and Inhibiting Inflammation
Cells, 2021 High mobility group box 1 protein (HMGB1), a highly conserved nuclear DNA-binding protein, is a “damage-associated molecular pattern” molecule (DAMP) implicated in both stimulating and inhibiting innate immunity.
Ulf Andersson +2 more
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Formin nanoclustering-mediated actin assembly during plant flagellin and DSF signaling
Cell Reports, 2021 Summary: Plants respond to bacterial infection acutely with actin remodeling during plant immune responses. The mechanisms by which bacterial virulence factors (VFs) modulate plant actin polymerization remain enigmatic.
Zhiming Ma +7 more
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