Results 11 to 20 of about 391,643 (293)

Identification of CNS Injury-Related microRNAs as Novel Toll-Like Receptor 7/8 Signaling Activators by Small RNA Sequencing [PDF]

, 2020
Toll-like receptors (TLRs) belong to pattern recognition receptors, which respond to danger signals such as pathogen-associated molecular patterns or damage-associated molecular patterns.
Buonfiglioli, Alice, Dembny, Paul, Krüger, Christina, Lehnardt, Seija, Prinz, Marco, Staszewski, Ori, Wallach, Thomas, Wetzel, Max   +7 more
core   +1 more source

The Role of C-Type Lectin Receptor Signaling in the Intestinal Microbiota-Inflammation-Cancer Axis

Frontiers in Immunology, 2022
As a subset of pattern recognition receptors (PRRs), C-type lectin-like receptors (CLRs) are mainly expressed by myeloid cells as both transmembrane and soluble forms.
Muhan Li, Muhan Li, Runfeng Zhang, Runfeng Zhang, Ji Li, Ji Li, Jingnan Li, Jingnan Li   +7 more
doaj   +1 more source

Bacterial Translocation in Gastrointestinal Cancers and Cancer Treatment

Biomedicines, 2022
In recent years, there has been increasing evidence that gut microbiota is associated with the onset and exacerbation of various diseases, such as gastrointestinal cancer.
Keita Kouzu, Hironori Tsujimoto, Yoji Kishi, Hideki Ueno, Nariyoshi Shinomiya   +4 more
doaj   +1 more source

Kawasaki Disease Following Severe Sunburn Injury

Frontiers in Pediatrics, 2020
Background: Although an etiology of Kawasaki disease (KD) is unknown, an aberrant innate immune system in predisposed individuals has been proposed to play a key role in the development of KD vasculitis.
Seigo Okada, Seigo Okada, Shintaro Hashimoto, Akiko Miyake, Yusuke Okada, Reiji Hirano, Shinnosuke Fukunaga, Yuichi Ishikawa   +7 more
doaj   +1 more source

Activation and regulation mechanisms of NOD-like receptors based on structural biology

Frontiers in Immunology, 2022
Innate immunity is a primary defense system against microbial infections. Innate immune pattern recognition receptors (PRRs) play pivotal roles in detection of invading pathogens.
Umeharu Ohto
doaj   +1 more source

State of the Art of Innate Immunity—An Overview

Cells, 2022
The innate immune system is the first line of defense against bacterial and viral infections and sterile inflammation through the recognition of pathogen-associated molecular patterns (PAMPs) as well as danger-associated molecular patterns (DAMPs) by ...
Silvia Fischer, Elisabeth Deindl
doaj   +1 more source

Inflammation-induced DNA damage and damage-induced inflammation: a vicious cycle [PDF]

, 2014
Inflammation is the ultimate response to the constant challenges of the immune system by microbes, irritants or injury. The inflammatory cascade initiates with the recognition of microorganism-derived pathogen associated molecular patterns (PAMPs) and ...
Abe, Alexeyev, Andersson, Andersson, Ba, Babior, Bartoloni, Berger, Blyth, Brill, Brinkmann, Cadet, Collins, Cooke, Csanád Z. Bachrati, David, Ding, Dostert, Ermakov, Ermakov, Ferguson, Fuchs, Gahan, Gedik, Gehrke, Hajizadeh, Halle, Hiramoto, Huang, Huang, Huang, Huttunen, Ishikawa, Ivana, Ivanov, Jahr, Jia, Kang, Kanneganti, Kazak, Klebanoff, Knaapen, Kondo, Kostyuk, Kostyuk, Krieg, Kuechle, Lane, Lange, Latz, Li, Malins, Mariathasan, Munoz-Gamez, Nakahira, Oka, Pacher, Parvatiyar, Pasheva, Pinti, Polk, Rathinam, Saitoh, Saxena, Scaffidi, Schroder, Shimada, Shokolenko, Sun, Suter, Suzuki, Swindall, Tadie, Taguchi, Takeda, Takeda, Tang, Tang, Thomson, Timea Pálmai-Pallag, Unterholzner, Urbonaviciute, Venereau, Volcic, Weinberg, Weiss, Wilson, Wu, Yan, Yang, Yoshida, Yoshihara, Yotsumoto, You, Yousefi, Zhang, Zhang, Zhang, Zhang, Zhang, Zhou   +100 more
core   +1 more source

GRP-3 and KAPP, encoding interactors of WAK1, negatively affect defense responses induced by oligogalacturonides and local response to wounding [PDF]

, 2016
Conserved microbe-associated molecular patterns (MAMPs) and damage-associated molecular patterns (DAMPs) act as danger signals to activate the plant immune response.
CERVONE, Felice, DE LORENZO, Giulia, GRAMEGNA, GIOVANNA, MODESTI, VANESSA, SAVATIN, DANIEL VALENTIN, SICILIA, Francesca   +5 more
core   +1 more source

Role of Translocation of Pathogen-Associated Molecular Patterns in Sepsis [PDF]

Digestive Surgery, 2009
<i>Background/Aim:</i> Unlike animals, the incidence of bacterial translocation and its clinical significance remain to be determined in humans, which may be due to the lack of accurate methods to confirm and monitor bacterial translocation. The literature on the consequences of novel insights of bacterial translocation was reviewed.
Hironori, Tsujimoto, Satoshi, Ono, Hidetaka, Mochizuki   +2 more
openaire   +2 more sources

Characterization of the Xanthomonas campestris pv. campestris Lipopolysaccharide Substructures Essential for Elicitation of an Oxidative Burst in Tobacco Cells

Molecular Plant-Microbe Interactions, 2005
The lipopolysaccharides (LPS) of gram-negative bacteria are essential for perception of pathogens by animals and plants. To identify the LPS substructure or substructures recognized by plants, we isolated water-phase (w)LPS from different Xanthomonas ...
Sebastian G. Braun, Andreas Meyer, Otto Holst, Alfred Pühler, Karsten Niehaus   +4 more
doaj   +1 more source