Results 11 to 20 of about 44,783 (256)

Effects of low dose GM-CSF on microglial inflammatory profiles to diverse pathogen-associated molecular patterns (PAMPs) [PDF]

Journal of Neuroinflammation, 2007
Background It is well appreciated that obtaining sufficient numbers of primary microglia for in vitro experiments has always been a challenge for scientists studying the biological properties of these cells.
Kielian Tammy, Esen Nilufer
doaj   +4 more sources

Effects of bacterial and viral pathogen-associated molecular patterns (PAMPs) on multidrug resistance (MDR) transporters in brain endothelial cells of the developing human blood-brain barrier. [PDF]

Fluids Barriers CNS, 2023
Abstract Background The multidrug resistance (MDR) transporters, P-glycoprotein (P-gp, encoded by ABCB1) and breast cancer resistance protein (BCRP/ABCG2) contribute to the blood–brain barrier (BBB), protecting the brain from drug exposure.
Lye P, Bloise E, Matthews SG.
europepmc   +4 more sources

A new paradigm: 46 structural cell types function as environment-supporting innate immune cells, with endothelial and vascular smooth muscle cells as key prototypes. [PDF]

Inew Med
ABSTRACT The scope, organization, and biological significance of innate immune functions across structural cell types remain poorly defined. To address these fundamental knowledge gaps, we analyzed experimental data of transcriptomes generated by our group and others.
Liu J, Nanayakkara GK, Lu Y, Saaoud F, Xu K, Shao Y, Yuan B, Hung SY, Xiang H, Wang X, Mohsin S, Wu S, Liu X, Wei J, Zhou Z, Kosmider B, Fu M, Martinez L, Vazquez-Padron R, Hu W, Ge S, Wang H, Yang X.   +22 more
europepmc   +2 more sources

Assay for Pathogen-Associated Molecular Pattern (PAMP)-Triggered Immunity (PTI) in Plants [PDF]

Journal of Visualized Experiments, 2009
To perceive potential pathogens in their environment, plants use pattern recognition receptors (PRRs) present on their plasma membranes. PRRs recognize conserved microbial features called pathogen-associated molecular patterns (PAMPs) and this detection leads to PAMP-triggered immunity (PTI), which effectively prevents colonization of plant tissues by ...
Chakravarthy, Suma, Velásquez, André C., Martin, Gregory B.   +2 more
openaire   +2 more sources

Herpesviruses dUTPases: A New Family of Pathogen-Associated Molecular Pattern (PAMP) Proteins with Implications for Human Disease [PDF]

Pathogens, 2016
The human herpesviruses are ubiquitous viruses and have a prevalence of over 90% in the adult population. Following a primary infection they establish latency and can be reactivated over a person’s lifetime. While it is well accepted that human herpesviruses are implicated in numerous diseases ranging from dermatological and autoimmune disease to ...
Marshall Williams, Brandon Cox, Maria Ariza   +2 more
openaire   +3 more sources

Real-time PCR Analysis of PAMP-induced Marker Gene Expression in Nicotiana benthamiana

Bio-Protocol, 2018
Perception of pathogen-associated molecular patterns (PAMPs) often triggers various innate immune responses in plants. The transcriptional changes of defense-related genes are often used as a marker to assay PAMP-triggered plant immune response.
Fan Liu, Yuanpeng Xu, Yuanchao Wang, Yuanchao Wang   +3 more
doaj   +1 more source

A new proteinaceous pathogen‐associated molecular pattern (PAMP) identified in Ascomycete fungi induces cell death in Solanaceae [PDF]

New Phytologist, 2017
Summary Pathogen‐associated molecular patterns (PAMPs) are detected by plant pattern recognition receptors (PRRs), which gives rise to PAMP‐triggered immunity (PTI). We characterized a novel fungal PAMP, Cell Death Inducing 1 (RcCDI1), identified in the Rhynchosporium commune transcriptome sampled at an early stage of barley (Hordeum vulgare ...
Franco-Orozco, B., Berepiki, A., Ruiz, O., Gamble, L., Griffe, L. L., Wang, S., Birch, P. R. J., Kanyuka, K., Avrova, A.   +8 more
openaire   +3 more sources

Recognition of damage-associated, nucleic acid-related molecular patterns during inflammation and vaccination

Frontiers in Cellular and Infection Microbiology, 2013
All mammalian cells are equipped with large numbers of sensors for protection from various sorts of invaders, who, in turn, are equipped with molecules containing pathogen-associated molecular patterns (PAMPs).
Nao eJounai, Nao eJounai, Kouji eKobiyama, Kouji eKobiyama, Fumihiko eTakeshita, Fumihiko eTakeshita, Ken J. Ishii, Ken J. Ishii   +7 more
doaj   +1 more source

PAMPs of Piscirickettsia salmonis Trigger the Transcription of Genes Involved in Nutritional Immunity in a Salmon Macrophage-Like Cell Line

Frontiers in Immunology, 2022
The innate immune system can limit the growth of invading pathogens by depleting micronutrients at a cellular and tissue level. However, it is not known whether nutrient depletion mechanisms discriminate between living pathogens (which require nutrients)
Danixa Pamela Martínez, Danixa Pamela Martínez, Cristian Oliver, Natacha Santibañez, José Leonardo Coronado, Ricardo Oyarzún-Salazar, Ricardo Enriquez, Luis Vargas-Chacoff, Luis Vargas-Chacoff, Luis Vargas-Chacoff, Alex Romero, Alex Romero   +11 more
doaj   +1 more source

PAMP (Pathogen-associated Molecular Pattern)-induced Changes in Plasma Membrane Compartmentalization Reveal Novel Components of Plant Immunity [PDF]

Journal of Biological Chemistry, 2010
Plasma membrane compartmentalization spatiotemporally regulates cell-autonomous immune signaling in animal cells. To elucidate immediate early protein dynamics at the plant plasma membrane in response to the bacterial pathogen-associated molecular pattern (PAMP) flagellin (flg22) we employed quantitative mass spectrometric analysis on detergent ...
Keinath Nana F, Kierszniowska Sylwia, Lorek Justine, Bourdais Gildas, Kessler Sharon A, Shimosato-Asano Hiroko, Grossniklaus Ueli, Schulze Waltraud X, Robatzek Silke, Panstruga Ralph   +9 more
openaire   +5 more sources