Activated Carbon for Sepsis Prevention and Intervention: A Modern Way of Utilizing Old Therapies
C, 2023 (1) Background: Uncontrolled inflammation often contributes to life-threatening sepsis sequela such as multi-organ dysfunction syndrome (MODS), and is accompanied by abnormal levels of pathological and damage-associated molecular patterns (PAMPs & DAMPs)
Elisaveta Snezhkova +3 more
doaj +1 more source
Mechanisms of Immunothrombosis by SARS-CoV-2
Biomolecules, 2021 SARS-CoV-2 contains certain molecules that are related to the presence of immunothrombosis. Here, we review the pathogen and damage-associated molecular patterns.
María Teresa Hernández-Huerta +12 more
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The Role of C-Type Lectin Receptor Signaling in the Intestinal Microbiota-Inflammation-Cancer Axis
Frontiers in Immunology, 2022 As a subset of pattern recognition receptors (PRRs), C-type lectin-like receptors (CLRs) are mainly expressed by myeloid cells as both transmembrane and soluble forms.
Muhan Li +7 more
doaj +1 more source
Role of Translocation of Pathogen-Associated Molecular Patterns in Sepsis [PDF]
Digestive Surgery, 2009 <i>Background/Aim:</i> Unlike animals, the incidence of bacterial translocation and its clinical significance remain to be determined in humans, which may be due to the lack of accurate methods to confirm and monitor bacterial translocation. The literature on the consequences of novel insights of bacterial translocation was reviewed.
Hironori, Tsujimoto +2 more
openaire +2 more sources
Bacterial Translocation in Gastrointestinal Cancers and Cancer Treatment
Biomedicines, 2022 In recent years, there has been increasing evidence that gut microbiota is associated with the onset and exacerbation of various diseases, such as gastrointestinal cancer.
Keita Kouzu +4 more
doaj +1 more source
Natural and synthetic pathogen associated molecular patterns modulate galectin expression in cow blood. [PDF]
J Anim Sci Technol, 2019 Pathogen-associated Molecular Patterns (PAMPs) are highly conserved structural motifs that are recognized by Pathogen Recognition receptors (PRRs) to initiate immune responses.
Asiamah EK +5 more
europepmc +2 more sources
Kawasaki Disease Following Severe Sunburn Injury
Frontiers in Pediatrics, 2020 Background: Although an etiology of Kawasaki disease (KD) is unknown, an aberrant innate immune system in predisposed individuals has been proposed to play a key role in the development of KD vasculitis.
Seigo Okada +7 more
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Damage- and Pathogen-Associated Molecular Patterns and Alarmins: Keys to Sepsis? [PDF]
European Surgical Research, 2012 The concept that sepsis is the result of an uncontrolled inflammatory response of the host’s innate immune system towards invading pathogens has recently been challenged. Evidence is accumulating that, in addition, host-derived alarm molecules are released during sepsis- and trauma-associated cell death, thus triggering the host’s immune response.
Denk, S. +2 more
openaire +3 more sources
Activation and regulation mechanisms of NOD-like receptors based on structural biology
Frontiers in Immunology, 2022 Innate immunity is a primary defense system against microbial infections. Innate immune pattern recognition receptors (PRRs) play pivotal roles in detection of invading pathogens.
Umeharu Ohto
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State of the Art of Innate Immunity—An Overview
Cells, 2022 The innate immune system is the first line of defense against bacterial and viral infections and sterile inflammation through the recognition of pathogen-associated molecular patterns (PAMPs) as well as danger-associated molecular patterns (DAMPs) by ...
Silvia Fischer, Elisabeth Deindl
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