Results 31 to 40 of about 633,152 (295)
Cell Reports, 2017 Receptor interacting protein kinase 3 (RIPK3) induces necroptosis, a type of regulated necrosis, through its kinase domain and receptor interacting protein (RIP) homotypic interaction motif (RHIM).
Kenta Moriwaki +4 more
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Cell Reports, 2016 Microvascular endothelial cells maintain a tight barrier to prevent passage of plasma and circulating immune cells into the extravascular tissue compartment, yet endothelial cells respond rapidly to vasoactive substances, including thrombin, allowing ...
Linda R. Klei +18 more
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Molecular Plant-Microbe Interactions, 2023 Plants rely on innate immune systems to defend against a wide variety of biotic attackers. Key components of innate immunity include cell-surface pattern-recognition receptors (PRRs), which recognize pest- and pathogen-associated molecular patterns ...
Anthony G. K. Garcia +1 more
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Intracellular pattern-recognition receptors☆
Advanced Drug Delivery Reviews, 2008 The last ten years of research in the field of innate immunity have been incredibly fertile: the transmembrane Toll-like receptors (TLRs) were discovered as guardians protecting the host against microbial attacks and the emerging pathways characterized in detail.
DOSTERT, C, Meylan, Etienne, Tschopp, J
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Pattern Recognition Receptors in HIV Transmission [PDF]
Frontiers in Immunology, 2012 Dendritic cells (DCs), Langerhans cells (LCs), and macrophages are innate immune cells that reside in genital and intestinal mucosal tissues susceptible to HIV-1 infection. These innate cells play distinct roles in initiation of HIV-1 infection and induction of anti-viral immunity. DCs are potent migratory cells that capture HIV-1 and transfer virus to
Mesman, Annelies W. +1 more
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Pattern-Recognition Receptors and Gastric Cancer [PDF]
Frontiers in Immunology, 2014 Chronic inflammation has been associated with an increased risk of several human malignancies, a classic example being gastric adenocarcinoma (GC). Development of GC is known to result from infection of the gastric mucosa by Helicobacter pylori, which initially induces acute inflammation and, in a subset of patients, progresses over time to chronic ...
Castaño-Rodríguez, N +2 more
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Human Dectin-1 is O-glycosylated and serves as a ligand for C-type lectin receptor CLEC-2
eLife, 2022 C-type lectin receptors (CLRs) elicit immune responses upon recognition of glycoconjugates present on pathogens and self-components. While Dectin-1 is the best-characterized CLR recognizing β-glucan on pathogens, the endogenous targets of Dectin-1 are ...
Shojiro Haji +12 more
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CLEC5A: A Promiscuous Pattern Recognition Receptor to Microbes and Beyond
Advances in Experimental Medicine and Biology, 2020 CLEC5A is a spleen tyrosine kinase (Syk)-coupled C-type lectin that is highly expressed by monocytes, macrophages, neutrophils, and dendritic cells and interacts with virions directly, via terminal fucose and mannose moieties of viral glycans.
Pei-Shan Sung, Wei-Chiao Chang, S. Hsieh
semanticscholar +1 more source
Fisheries and Aquatic Sciences, 2022 Galectins, a family of β-galactoside-binding lectins, have emerged as soluble mediators in infected cells and pattern recognition receptors (PRRs) responsible for evoking and regulating innate immunity.
Chaehyeon Lim, Hyukjae Kwon, Jehee Lee
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Pattern recognitions receptors in immunodeficiency disorders [PDF]
European Journal of Pharmacology, 2017 Pattern recognition receptors (PRRs) recognize common microbial or host-derived macromolecules and have important roles in early activation and response of the immune system. Initiation of the innate immune response starts with the recognition of microbial structures called pathogen associated molecular patterns (PAMPs).
Mortaz, E +7 more
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