Results 11 to 20 of about 401,055 (285)
Pattern recognition receptors and autophagy [PDF]
Frontiers in Immunology, 2014 The immune system senses exogenous threats or endogenous stress through specialized machinery known as pattern recognition receptors (PRRs). These receptors recognize conserved molecular structures and initiate downstream signaling pathways to control ...
Ji Eun eOh, Heung Kyu eLee
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Pattern recognition receptors in HIV transmission [PDF]
Frontiers in Immunology, 2012 Dendritic cells (DCs), Langerhans cells (LCs) and macrophages are innate immune cells that reside in genital and intestinal mucosal tissues susceptible to HIV-1 infection.
Teunis B. Geijtenbeek, Annelies eMesman
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Pattern recognition receptors and gastric cancer [PDF]
Frontiers in Immunology, 2014 Chronic inflammation has been associated with an increased risk of several human malignancies, a classic example being gastric cancer (GC). Development of GC is known to result from infection of the gastric mucosa by Helicobacter pylori, which initially ...
Natalia eCastaño-Rodriguez +2 more
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Pattern recognition receptors in antifungal immunity [PDF]
Seminars in Immunopathology, 2014 Receptors of the innate immune system are the first line of defence against infection, being able to recognise and initiate an inflammatory response to invading microorganisms. The Toll-like (TLR), NOD-like (NLR), RIG-I-like (RLR) and C-type lectin-like receptors (CLR) are four receptor families that contribute to the recognition of a vast range of ...
Plato, Anthony +2 more
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Pattern recognition receptors in health and diseases [PDF]
Signal Transduction and Targeted Therapy, 2021 Pattern recognition receptors (PRRs) are a class of receptors that can directly recognize the specific molecular structures on the surface of pathogens, apoptotic host cells, and damaged senescent cells.
Danyang Li, Minghua Wu
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PRRDB: A comprehensive database of Pattern-Recognition Receptors and their ligands [PDF]
BMC Genomics, 2008 Background Recently in a number of studies, it has been demonstrated that the innate immune system doesn't merely acts as the first line of defense but provides critical signals for the development of specific adaptive immune response.
Lata Sneh, Raghava Gajendra
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Editorial: Pattern-recognition receptors: Genetics, immunity, pathology [PDF]
Frontiers in Cellular and Infection Microbiology, 2022 Petro Starokadomskyy
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cGLRs are a diverse family of pattern recognition receptors in innate immunity [PDF]
Cell, 2023 Desmond Richmond-Buccola
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Inhibitory pattern recognition receptors. [PDF]
J Exp Med, 2022 Pathogen- and damage-associated molecular patterns are sensed by the immune system’s pattern recognition receptors (PRRs) upon contact with a microbe or damaged tissue. In situations such as contact with commensals or during physiological cell death, the immune system should not respond to these patterns.
Rumpret M +3 more
europepmc +3 more sources
Pattern recognition receptors as a double-edged sword in cancer
Frontiers in Immunology, 2015 The problem of cancer remains one of the most immense challenges to current biomedical research. Affecting populations in all countries and all regions, this disease is responsible for millions of deaths annually (1). Evasion of the immune system is an ominous feature of cancers, which often leads to tumor outgrowth, epithelial–mesenchymal transition ...
Anton G. Kutikhin, Arseniy E Yuzhalin
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