Results 11 to 20 of about 639,618 (274)
Pattern Recognition Receptors and Inflammation [PDF]
Cell, 2010 Infection of cells by microorganisms activates the inflammatory response. The initial sensing of infection is mediated by innate pattern recognition receptors (PRRs), which include Toll-like receptors, RIG-I-like receptors, NOD-like receptors, and C-type lectin receptors.
Shizuo Akira, Osamu Takeuchi
exaly +4 more sources
Pattern recognition receptors and autophagy [PDF]
Frontiers in Immunology, 2014 The immune system senses exogenous threats or endogenous stress through specialized machinery known as pattern recognition receptors (PRRs). These receptors recognize conserved molecular structures and initiate downstream signaling pathways to control ...
Ji Eun eOh, Heung Kyu eLee
doaj +4 more sources
Pattern recognition receptors in HIV transmission [PDF]
Frontiers in Immunology, 2012 Dendritic cells (DCs), Langerhans cells (LCs) and macrophages are innate immune cells that reside in genital and intestinal mucosal tissues susceptible to HIV-1 infection.
Teunis B. Geijtenbeek, Annelies eMesman
doaj +3 more sources
Pattern recognition receptors and gastric cancer [PDF]
Frontiers in Immunology, 2014 Chronic inflammation has been associated with an increased risk of several human malignancies, a classic example being gastric cancer (GC). Development of GC is known to result from infection of the gastric mucosa by Helicobacter pylori, which initially ...
Natalia eCastaño-Rodriguez +2 more
doaj +4 more sources
Innate Immunity Crosstalk with Helicobacter pylori: Pattern Recognition Receptors and Cellular Responses. [PDF]
Int J Mol Sci, 2022 Helicobacter pylori is one of the most successful gastric pathogens that has co-existed with human for centuries. H. pylori is recognized by the host immune system through human pattern recognition receptors (PRRs), such as toll-like receptors (TLRs), C ...
Cheok YY +5 more
europepmc +2 more sources
Are Pattern Recognition Receptors Associated with Hepatocellular Carcinoma? [PDF]
The Turkish Journal of Gastroenterology, 2021 Background: Hepatocellular carcinoma (HCC) is one of the important causes of mortality due to malignancy. Toll-like receptors (TLRs) are very important in liver pathophysiology in terms of their roles in the innate immune system, such as the regulation ...
Ramazan Dertli +7 more
doaj +2 more sources
Control of adaptive immunity by pattern recognition receptors. [PDF]
ImmunityOne of the most significant conceptual advances in immunology in recent history is the recognition that signals from the innate immune system are required for induction of adaptive immune responses.
Carroll SL, Pasare C, Barton GM.
europepmc +2 more sources
Pattern recognition receptors as therapeutic targets for bacterial, viral and fungal sepsis
International Immunopharmacology, 2021 Sepsis remains to be a significant health care problem associated with high morbidities and mortalities. Recognizing its heterogeneity, it is critical to understand our host immunological responses to develop appropriate therapeutic approaches according ...
Koichi Yuki, Sophia Koutsogiannaki
exaly +2 more sources
"Open Sesame" to the complexity of pattern recognition receptors of myeloid-derived suppressor cells in cancer [PDF]
Frontiers in Immunology, 2023 Pattern recognition receptors are primitive sensors that arouse a preconfigured immune response to broad stimuli, including nonself pathogen-associated and autologous damage-associated molecular pattern molecules.
Tian Wang +6 more
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Herpes Simplex Virus and Pattern Recognition Receptors: An Arms Race
Frontiers in Immunology, 2021 Herpes simplex viruses (HSVs) are experts in establishing persistent infection in immune-competent humans, in part by successfully evading immune activation through diverse strategies. Upon HSV infection, host deploys pattern recognition receptors (PRRs)
Jun Zhao +4 more
doaj +2 more sources