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Expression of pattern recognition receptors in cholesteatoma
European Archives of Oto-Rhino-Laryngology, 2013Although many immunologic mechanisms have been investigated in studies of the pathogenesis of cholesteatoma, the role of pattern recognition receptors (PRRs) has not been fully determined. Therefore, we assessed innate immune responses in patients with cholesteatoma. We prospectively evaluated 21 patients with acquired cholesteatoma between August 2010
Ho Yun, Lee +4 more
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Pattern recognition receptor function in neutrophils
Trends in Immunology, 2013Previously, neutrophils were largely ignored in the pattern recognition receptor (PRR) signaling field. However, interest in neutrophil biology has been revitalized by emerging roles for neutrophils in promoting protective and pathogenic T helper (Th)17-driven immune responses and in orchestrating innate and adaptive immunity via cytokine/chemokine ...
Thomas, Christina J., Schroder, Kate
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Pattern Recognition by Toll-like Receptors
2009The mammalian immune system senses pathogens through pattern recognition receptors and responds with activation. The Toll-like receptors (TLRs) that are expressed on antigen presenting cells such as macrophages and dendritic cells play a critical role in this process.
Stefan, Bauer +2 more
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Pattern Recognition Receptors in Plant Immunity
Plant innate immunity is an advanced defense system to counteract pathogenic stresses. It relies on the recognition of microbial invasion through cell surface-localized pattern recognition receptors (PRRs) and intracellular nucleotide-binding domain leucine-rich repeat receptors (NLRs).Mughair, Abdul Aziz +2 more
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Pattern Recognition by NOD-Like Receptors
Nucleotide-binding oligomerization domain-like receptors (NLRs) are a family of cytosolic pattern recognition receptors (PRRs) and able to respond to conserved microbe-associated molecular patterns (MAMPs) and endogenous damage-associated molecular patterns (DAMPs).Timo-Daniel, Voss +2 more
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Therapeutic targeting of pattern-recognition receptors
International Immunopharmacology, 2006Innate immune system could recognize the pathogen-associated molecular patterns by pattern-recognition receptors like Toll-like receptor (TLR) and nucleotide-binding oligomerisation domain (NOD) protein. Information regarding the structure and signalling pathways of TLRs and NODs could provide opportunities for new therapeutic approaches to modulate ...
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Pattern Recognition Receptor Antagonism
Science Signaling, 2014A pathogenic fungus activates two C-type lectin receptors to skew the T cell response to one favorable to infection.
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WSA03 ‐ Pattern Recognition Receptors
European Journal of Immunology, 2009AbstractNo ...
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Pattern Recognition Receptors in Autoinflammation
2019The immune system is essential for maintenance of tissue homeostasis. This task requires that immune cells detect and respond to dyshomeostatic states (when homeostasis has broken down) that can occur during invasion of the host with pathogenic microbes, after sterile trauma of tissues or during metabolic derangements.
Saavedra, Victor +3 more
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Context-dependent functions of pattern recognition receptors in cancer
Nature Reviews Cancer, 2022Si Ming Man, Brendan J Jenkins
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