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Expression of pattern recognition receptors in cholesteatoma

European Archives of Oto-Rhino-Laryngology, 2013
Although many immunologic mechanisms have been investigated in studies of the pathogenesis of cholesteatoma, the role of pattern recognition receptors (PRRs) has not been fully determined. Therefore, we assessed innate immune responses in patients with cholesteatoma. We prospectively evaluated 21 patients with acquired cholesteatoma between August 2010
Ho Yun, Lee   +4 more
openaire   +2 more sources

Pattern recognition receptor function in neutrophils

Trends in Immunology, 2013
Previously, neutrophils were largely ignored in the pattern recognition receptor (PRR) signaling field. However, interest in neutrophil biology has been revitalized by emerging roles for neutrophils in promoting protective and pathogenic T helper (Th)17-driven immune responses and in orchestrating innate and adaptive immunity via cytokine/chemokine ...
Thomas, Christina J., Schroder, Kate
openaire   +5 more sources

Pattern Recognition by Toll-like Receptors

2009
The mammalian immune system senses pathogens through pattern recognition receptors and responds with activation. The Toll-like receptors (TLRs) that are expressed on antigen presenting cells such as macrophages and dendritic cells play a critical role in this process.
Stefan, Bauer   +2 more
openaire   +2 more sources

Pattern Recognition Receptors in Plant Immunity

Plant innate immunity is an advanced defense system to counteract pathogenic stresses. It relies on the recognition of microbial invasion through cell surface-localized pattern recognition receptors (PRRs) and intracellular nucleotide-binding domain leucine-rich repeat receptors (NLRs).
Mughair, Abdul Aziz   +2 more
openaire   +2 more sources

Pattern Recognition by NOD-Like Receptors

Nucleotide-binding oligomerization domain-like receptors (NLRs) are a family of cytosolic pattern recognition receptors (PRRs) and able to respond to conserved microbe-associated molecular patterns (MAMPs) and endogenous damage-associated molecular patterns (DAMPs).
Timo-Daniel, Voss   +2 more
openaire   +2 more sources

Therapeutic targeting of pattern-recognition receptors

International Immunopharmacology, 2006
Innate immune system could recognize the pathogen-associated molecular patterns by pattern-recognition receptors like Toll-like receptor (TLR) and nucleotide-binding oligomerisation domain (NOD) protein. Information regarding the structure and signalling pathways of TLRs and NODs could provide opportunities for new therapeutic approaches to modulate ...
openaire   +2 more sources

Pattern Recognition Receptor Antagonism

Science Signaling, 2014
A pathogenic fungus activates two C-type lectin receptors to skew the T cell response to one favorable to infection.
openaire   +1 more source

WSA03 ‐ Pattern Recognition Receptors

European Journal of Immunology, 2009
AbstractNo ...
openaire   +1 more source

Pattern Recognition Receptors in Autoinflammation

2019
The immune system is essential for maintenance of tissue homeostasis. This task requires that immune cells detect and respond to dyshomeostatic states (when homeostasis has broken down) that can occur during invasion of the host with pathogenic microbes, after sterile trauma of tissues or during metabolic derangements.
Saavedra, Victor   +3 more
openaire   +2 more sources

Context-dependent functions of pattern recognition receptors in cancer

Nature Reviews Cancer, 2022
Si Ming Man, Brendan J Jenkins
exaly  

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